Brief Information of the Cell Line and Protein
Cell Line ID: CL000442 , Cf2Th-CCR5
Synonyms
Cf2Th/syn CCR5
Cf2Th/PACH/synCCR5
Cf2Th synCCR5+
Category Spontaneously immortalized cell line
Organism
Canis lupus familiaris (Dog)
Cellosaurus ID
CVCL_1G50
Protein ID: PT03571 , Envelope glycoprotein gp160
Gene Name ENV
Organism Human immunodeficiency virus type 1 group M subtype B (isolate HXB2), HIV-1
Protein Classification Surface antigen
Uniprot ID P04578
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000442  Protein ID: PT03571
 
Compound ID Compound Name Compound Formula
CP0144831
N-(5-azaspiro[3.5]nonan-8-yl)-N'-(4-chloro-3-fluorophenyl)oxamide
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C16H19ClFN3O2
 2
1
IC50 = 9300 nM
   TI
   LI
   LO
   TS
2
IC50 = 86900 nM
   TI
   LI
   LO
   TS
CP0282807
N'-(4-chloro-3-fluorophenyl)-N-(2,2,6,6-tetramethylpiperidin-4-yl)oxamide
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C17H23ClFN3O2
 2
1
IC50 = 9600 nM
   TI
   LI
   LO
   TS
2
IC50 = 29100 nM
   TI
   LI
   LO
   TS
CP0282780
N'-(4-chloro-3-fluorophenyl)-N-[2-[(2S,6R)-2,6-dimethylpiperidin-1-yl]ethyl]oxamide
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C17H23ClFN3O2
 2
1
IC50 = 34500 nM
   TI
   LI
   LO
   TS
2
IC50 = 83200 nM
   TI
   LI
   LO
   TS