| Compound ID |
Compound Name |
Compound Formula |
|
CP0496585
|
1-(3,4-difluorophenyl)-3-(3-(2,3-dihydrospiro[indene-1,4'-piperidine]-1'-yl)propyl)-3-methyl-1-p-tolylurea
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|
C31H35F2N3O
|
1
|
| 1 |
IC50 = 230 nM
|
|
|
|
CP0429695
|
3-(3-(2,3-dihydrospiro[indene-1,4'-piperidine]-1'-yl)propyl)-1-(4-fluorophenyl)-1-p-tolylurea
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|
C30H34FN3O
|
1
|
| 1 |
IC50 = 340 nM
|
|
|
|
CP0431195
|
1-(3,4-difluorophenyl)-3-(3-(2,3-dihydrospiro[indene-1,4'-piperidine]-1'-yl)propyl)-1-p-tolylurea
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|
C30H33F2N3O
|
1
|
| 1 |
IC50 = 350 nM
|
|
|
|
CP0474042
|
1-(3-(3H-spiro[isobenzofuran-1,4'-piperidine]-1'-yl)propyl)-3-(3,4-difluorophenyl)-1-methyl-3-p-tolylurea
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|
C30H33F2N3O2
|
1
|
| 1 |
IC50 = 470 nM
|
|
|
|
CP0397321
|
3-(3-(2,3-dihydrospiro[indene-1,4'-piperidine]-1'-yl)propyl)-1-(3-fluorophenyl)-1-p-tolylurea
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|
C30H34FN3O
|
1
|
| 1 |
IC50 = 490 nM
|
|
|
|
CP0474041
|
3-(3-(2,3-dihydrospiro[indene-1,4'-piperidine]-1'-yl)propyl)-1,1-dip-tolylurea
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|
C31H37N3O
|
1
|
| 1 |
IC50 = 540 nM
|
|
|
|
CP0498305
|
(+/-)-N-(3-(3H-spiro[isobenzofuran-1,4'-piperidine]-1'-yl)propyl)-2-(3,4-difluorophenyl)-N-methyl-2-phenylacetamide
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|
C30H32F2N2O2
|
1
|
| 1 |
IC50 = 600 nM
|
|
|
|
CP0509248
|
1-(3-(3H-spiro[isobenzofuran-1,4'-piperidine]-1'-yl)propyl)-3-(3,4-difluorophenyl)-1-methyl-3-phenylurea
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|
C29H31F2N3O2
|
1
|
| 1 |
IC50 = 920 nM
|
|
|
|
CP0374401
|
(+/-)-N-(3-(3H-spiro[isobenzofuran-1,4'-piperidine]-1'-yl)propyl)-2-(3,4-difluorophenyl)-N-methyl-2-(2-oxopyrrolidin-1-yl)acetamide
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|
C28H33F2N3O3
|
1
|
| 1 |
IC50 = 1000 nM
|
|
|
|
CP0497557
|
(+/-)-N-(3-(3H-spiro[isobenzofuran-1,4'-piperidine]-1'-yl)propyl)-2-(3,4-difluorophenyl)-N-methyl-2-(pyrrolidin-1-yl)acetamide
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|
C28H35F2N3O2
|
1
|
| 1 |
IC50 = 1160 nM
|
|
|
|
CP0455395
|
(+/-)-N-(3-(3H-spiro[isobenzofuran-1,4'-piperidine]-1'-yl)propyl)-2-(3,4-difluorophenyl)-N-methyl-2-(1H-1,2,4-triazol-1-yl)acetamide
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|
C26H29F2N5O2
|
1
|
| 1 |
IC50 = 1910 nM
|
|
|
|
CP0514711
|
(+/-)-N-(3-(3H-spiro[isobenzofuran-1,4'-piperidine]-1'-yl)propyl)-2-(3,4-difluorophenyl)-N-methyl-2-(1H-tetrazol-1-yl)acetamide
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|
C25H28F2N6O2
|
1
|
| 1 |
IC50 = 1910 nM
|
|
|
|
CP0498456
|
(+/-)-N-(3-(3H-spiro[isobenzofuran-1,4'-piperidine]-1'-yl)propyl)-2-(3,4-difluorophenyl)-N-methyl-2-(1H-1,2,3-triazol-1-yl)acetamide
Show/Hide
|
C26H29F2N5O2
|
1
|
| 1 |
IC50 = 1920 nM
|
|
|
|
CP0474043
|
(+/-)-N-(3-(3'H-spiro[cyclohexane-1,1'-isobenzofuran]-4-yl)propyl)-2-(3,4-difluorophenyl)-N-methyl-2-(1H-pyrazol-1-yl)acetamide
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|
C28H31F2N3O2
|
1
|
| 1 |
IC50 = 3600 nM
|
|
|
|
CP0334663
|
2-(3,4-difluorophenyl)-N-(3-(6-fluoro-1H-spiro[furo[3,4-c]pyridine-3,4'-piperidine]-1'-yl)propyl)-N-(2-fluoroethyl)-2-(1H-pyrazol-1-yl)acetamide
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|
C27H29F4N5O2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0388488
|
(+/-)-2-(3,4-difluorophenyl)-N-(3-(6-fluoro-1H-spiro[furo[3,4-c]pyridine-3,4'-piperidine]-1'-yl)propyl)-N-methyl-2-(1H-pyrazol-1-yl)acetamide
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|
C26H28F3N5O2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0431196
|
2-(3,4-difluorophenyl)-N-ethyl-N-(3-(6-fluoro-1H-spiro[furo[3,4-c]pyridine-3,4'-piperidine]-1'-yl)propyl)-2-(1H-pyrazol-1-yl)acetamide
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|
C27H30F3N5O2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
