Brief Information of the Compound and Protein
Compound Name
(+/-)-N-(3-(3H-spiro[isobenzofuran-1,4'-piperidine]-1'-yl)propyl)-2-(3,4-difluorophenyl)-N-methyl-2-(2-oxopyrrolidin-1-yl)acetamide
    Show/Hide
PubChem ID
CID: 10391177
SID: 15406821
Canonical SMILES
CN(CCCN1CCC2(CC1)OCc1ccccc21)C(=O)C(N1CCCC1=O)c1ccc(F)c(F)c1
    Show/Hide
Compound Formula C28H33F2N3O3
Compound Structure
Protein Name
Alpha-1A adrenergic receptor
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Small molecule receptor (family A GPCR)
>
Monoamine receptor
>
Adrenergic receptor
Uniprot ID
P35348
Gene Name
ADRA1A
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000440 LM Homo sapiens (Human)  1
1
IC50 = 1000 nM
   TI
   LI
   LO
   TS