Brief Information of the Cell Line and Protein
Cell Line ID: CL000434 , KG-1
Synonyms
KG1
Category Cancer cell line
Organism
Homo sapiens (Human)
Cellosaurus ID
CVCL_0374
Protein ID: PT01346 , Tyrosine-protein phosphatase non-receptor type 11
Gene Name PTPN11
Organism Homo sapiens, Human
Protein Classification Enzyme
Uniprot ID Q06124
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000434  Protein ID: PT01346
 
Compound ID Compound Name Compound Formula
CP0384556
(2E)-3-{3-chloro-4-[3-(3,3-dimethylbut-1-yn-1-yl)-4-hydroxyphenyl]phenyl}prop-2-enoic acid
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C21H19ClO3
 1
1
IC50 = 450 nM
   TI
   LI
   LO
   TS
CP0095649
(2E)-3-{4-[3-(adamantan-1-yl)-4-aminophenyl]-3-chlorophenyl}prop-2-enoic acid
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C25H26ClNO2
 1
1
IC50 = 1830 nM
   TI
   LI
   LO
   TS
CP0052426
(2E)-3-{4-[3-(adamantan-1-yl)-4-hydroxyphenyl]-3-chlorophenyl}prop-2-enoic acid
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C25H25ClO3
 1
1
IC50 = 2100 nM
   TI
   LI
   LO
   TS
CP0166875
(2E)-3-{4-[3-(adamantan-1-yl)-4-fluorophenyl]-3-chlorophenyl}prop-2-enoic acid
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C25H24ClFO2
 1
1
IC50 = 2110 nM
   TI
   LI
   LO
   TS
CP0206772
(2E)-3-{3-chloro-4-[3-(3,5-dimethyladamantan-1-yl)-4-hydroxyphenyl]phenyl}prop-2-enoic acid
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C27H29ClO3
 1
1
IC50 = 2270 nM
   TI
   LI
   LO
   TS
CP0503035
(2E)-3-[3-chloro-4-(4-hydroxy-3-{tricyclo[3.3.1.0^{3,7}]nonan-3-yl}phenyl)phenyl]prop-2-enoic acid
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C24H23ClO3
 1
1
IC50 = 3910 nM
   TI
   LI
   LO
   TS
CP0247307
(2E)-3-{4-[3-(adamantan-1-yl)-4-acetamidophenyl]-3-chlorophenyl}prop-2-enoic acid
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C27H28ClNO3
 1
1
IC50 = 4550 nM
   TI
   LI
   LO
   TS
CP0064470
(2E)-3-{3-chloro-4-[3-(3-ethylpentan-3-yl)-4-hydroxyphenyl]phenyl}prop-2-enoic acid
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C22H25ClO3
 1
1
IC50 = 5370 nM
   TI
   LI
   LO
   TS
CP0373216
(2E)-3-{3-chloro-4-[4-hydroxy-3-(1-methylcyclohexyl)phenyl]phenyl}prop-2-enoic acid
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C22H23ClO3
 1
1
IC50 = 6400 nM
   TI
   LI
   LO
   TS
CP0526919
(2E)-3-{3-chloro-4-[4-hydroxy-3-(2-methyl-1,3-dithian-2-yl)phenyl]phenyl}prop-2-enoic acid
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C20H19ClO3S2
 1
1
IC50 = 10200 nM
   TI
   LI
   LO
   TS
CP0484751
(2E)-3-{3-chloro-4-[3-(2,6-dimethylphenyl)-4-hydroxyphenyl]phenyl}prop-2-enoic acid
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C23H19ClO3
 1
1
IC50 = 19900 nM
   TI
   LI
   LO
   TS