Brief Information of the Cell Line and Protein
Cell Line ID: CL000384 , 3T3-L1
Synonyms
3T3 L1
3T3L1
3T3-L1 ad
NIH-3T3-L1
NIH3T3-L1
Category Spontaneously immortalized cell line
Organism
Mus musculus (Mouse)
Cellosaurus ID
CVCL_0123
Protein ID: PT02560 , Diacylglycerol O-acyltransferase 1
Gene Name DGAT1
Organism Mus musculus, Mouse
Protein Classification Enzyme
Uniprot ID Q9Z2A7
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000384  Protein ID: PT02560
 
Compound ID Compound Name Compound Formula
CP0497337
2,2-dimethyl-3-[5-[4-(naphthalene-2-carbonylamino)phenyl]pyridin-2-yl]oxypropanoic acid
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C27H24N2O4
 1
1
IC50 = 37 nM
   TI
   LI
   LO
   TS
CP0441331
2,2-dimethyl-3-[4-[4-(naphthalene-2-carbonylamino)phenyl]phenoxy]propanoic acid
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C28H25NO4
 1
1
IC50 = 102 nM
   TI
   LI
   LO
   TS
CP0452165
2,2-dimethyl-3-[5-[2-methyl-4-(naphthalene-2-carbonylamino)phenyl]pyridin-2-yl]oxypropanoic acid
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C28H26N2O4
 1
1
IC50 = 125 nM
   TI
   LI
   LO
   TS
CP0452113
N-[4-[5-(3-anilino-2,2-dimethyl-3-oxopropoxy)-4-methyl-1,2,4-triazol-3-yl]phenyl]naphthalene-2-carboxamide
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C31H29N5O3
 1
1
IC50 = 220 nM
   TI
   LI
   LO
   TS
CP0439980
2,2-dimethyl-3-[5-[2-methyl-4-(naphthalene-2-carbonylamino)phenyl]pyrimidin-2-yl]oxypropanoic acid
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C27H25N3O4
 1
1
IC50 = 433 nM
   TI
   LI
   LO
   TS
CP0452163
N-[4-[5-[3-(dimethylamino)-2,2-dimethyl-3-oxopropoxy]-4-methyl-1,2,4-triazol-3-yl]phenyl]naphthalene-2-carboxamide
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C27H29N5O3
 1
1
IC50 = 440 nM
   TI
   LI
   LO
   TS
CP0431603
2,2-dimethyl-3-[6-[2-methyl-4-(naphthalene-2-carbonylamino)phenyl]pyridazin-3-yl]oxypropanoic acid
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C27H25N3O4
 1
1
IC50 = 709 nM
   TI
   LI
   LO
   TS
CP0431605
2,2-dimethyl-3-[[4-methyl-5-[4-(naphthalene-2-carbonylamino)phenyl]-1,2,4-triazol-3-yl]oxy]propanoic acid
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C25H24N4O4
 1
1
IC50 = 1960 nM
   TI
   LI
   LO
   TS
CP0495430
2,2-dimethyl-3-[5-[2-methyl-4-(naphthalene-2-carbonylamino)phenyl]pyrazin-2-yl]oxypropanoic acid
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C27H25N3O4
 1
1
IC50 = 2160 nM
   TI
   LI
   LO
   TS
CP0496053
N-[4-[5-[2,2-dimethyl-3-oxo-3-(propan-2-ylamino)propoxy]-4-methyl-1,2,4-triazol-3-yl]phenyl]naphthalene-2-carboxamide
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C28H31N5O3
 1
1
IC50 = 2340 nM
   TI
   LI
   LO
   TS
CP0388733
3-[4-methyl-5-[4-(naphthalene-2-carbonylamino)phenyl]-1,2,4-triazol-3-yl]propanoic acid
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C23H20N4O3
 1
1
IC50 = 4000 nM
   TI
   LI
   LO
   TS
CP0452107
N-[4-[5-[3-[2-(dimethylamino)ethylamino]-2,2-dimethyl-3-oxopropoxy]-4-methyl-1,2,4-triazol-3-yl]phenyl]naphthalene-2-carboxamide
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C29H34N6O3
 1
1
IC50 = 5890 nM
   TI
   LI
   LO
   TS
CP0467488
N-[4-[5-(3-amino-2,2-dimethyl-3-oxopropoxy)-4-methyl-1,2,4-triazol-3-yl]phenyl]naphthalene-2-carboxamide
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C25H25N5O3
 1
1
IC50 = 6100 nM
   TI
   LI
   LO
   TS
CP0496052
2-[[4-methyl-5-[4-(naphthalene-2-carbonylamino)phenyl]-1,2,4-triazol-3-yl]oxy]propanoic acid
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C23H20N4O4
 1
1
IC50 > 10000 nM
   TI
   LI
   LO
   TS
CP0260349
2-[[4-methyl-5-[4-[(2-methylbenzoyl)amino]phenyl]-1,2,4-triazol-3-yl]sulfanyl]propanoic acid
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C20H20N4O3S
 1
1
IC50 > 20000 nM
   TI
   LI
   LO
   TS
CP0388731
2-[[5-[4-[(3,4-dichlorobenzoyl)amino]phenyl]-4-methyl-1,2,4-triazol-3-yl]sulfanyl]butanoic acid
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C20H18Cl2N4O3S
 1
1
IC50 > 20000 nM
   TI
   LI
   LO
   TS
CP0388732
2-[[5-[4-(1-benzothiophene-2-carbonylamino)phenyl]-4-methyl-1,2,4-triazol-3-yl]sulfanyl]propanoic acid
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C21H18N4O3S2
 1
1
IC50 > 20000 nM
   TI
   LI
   LO
   TS
CP0416981
2-[[5-[4-[(3,4-dichlorobenzoyl)amino]phenyl]-4-methyl-1,2,4-triazol-3-yl]sulfanyl]-2-phenylacetic acid
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C24H18Cl2N4O3S
 1
1
IC50 > 20000 nM
   TI
   LI
   LO
   TS
CP0427505
2-[[5-[4-[[2-(3,4-dichlorophenyl)acetyl]amino]phenyl]-4-methyl-1,2,4-triazol-3-yl]sulfanyl]propanoic acid
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C20H18Cl2N4O3S
 1
1
IC50 > 20000 nM
   TI
   LI
   LO
   TS
CP0427507
2-[[4-methyl-5-[4-[(4-methylbenzoyl)amino]phenyl]-1,2,4-triazol-3-yl]sulfanyl]propanoic acid
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C20H20N4O3S
 1
1
IC50 > 20000 nM
   TI
   LI
   LO
   TS
CP0439981
2-[[4-methyl-5-[4-(naphthalene-2-carbonylamino)phenyl]-1,2,4-triazol-3-yl]sulfanyl]propanoic acid
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C23H20N4O3S
 1
1
IC50 > 20000 nM
   TI
   LI
   LO
   TS
CP0452164
2-[[5-[4-[(3,4-dichlorobenzoyl)amino]phenyl]-4-methyl-1,2,4-triazol-3-yl]sulfanyl]propanoic acid
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C19H16Cl2N4O3S
 1
1
IC50 > 20000 nM
   TI
   LI
   LO
   TS
CP0476412
2-[[5-(4-benzamidophenyl)-4-methyl-1,2,4-triazol-3-yl]sulfanyl]propanoic acid
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C19H18N4O3S
 1
1
IC50 > 20000 nM
   TI
   LI
   LO
   TS