Brief Information of the Cell Line and Protein
Cell Line ID: CL000380 , HCC827
Synonyms
HCC-827
HCC 827
HCC0827
Hamon Cancer Center 827
Category Cancer cell line
Organism
Homo sapiens (Human)
Cellosaurus ID
CVCL_2063
Protein ID: PT01141 , Focal adhesion kinase 1
Gene Name PTK2
Organism Homo sapiens, Human
Protein Classification Kinase
Uniprot ID Q05397
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000380  Protein ID: PT01141
 
Compound ID Compound Name Compound Formula
CP0059911
2-[[5-chloro-2-[[(6S)-6-[4-(2-hydroxyethyl)piperazin-1-yl]-1-methoxy-6,7,8,9-tetrahydro-5H-benzo[7]annulen-2-yl]amino]pyrimidin-4-yl]amino]-N-methylbenzamide
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C30H38ClN7O3
 1
1
IC50 = 80 nM
   TI
   LI
   LO
   TS
CP0089290
(1S,2S,3R,4R)-3-[[5-chloro-2-[[(7S)-4-methoxy-7-morpholin-4-yl-6,7,8,9-tetrahydro-5H-benzo[7]annulen-3-yl]amino]pyrimidin-4-yl]amino]bicyclo[2.2.1]hept-5-ene-2-carboxamide
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C28H35ClN6O3
 1
1
IC50 = 944 nM
   TI
   LI
   LO
   TS