| Compound ID |
Compound Name |
Compound Formula |
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CP0044854
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METHYLTRIENOLONE
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C19H24O2
|
1
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| 1 |
EC50 = 0.013 nM
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CP0390536
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2-chloro-4-[[(1R,2S)-2-hydroxy-2-methylcyclopentyl]amino]-3-methylbenzonitrile
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C14H17ClN2O
|
1
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| 1 |
EC50 = 0.0398 nM
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|
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CP0044960
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(1S,2S,7S,10R,11S,14S,15S)-14-hydroxy-2,15-dimethyltetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadecan-5-one
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C19H30O2
|
1
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| 1 |
EC50 = 0.13 nM
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CP0379783
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4-[(3S,3aR,4R)-4-fluoro-3-methoxy-3a,4,5,6-tetrahydro-3H-pyrrolo[1,2-b]pyrazol-2-yl]-2-chloro-3-methylbenzonitrile
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C15H15ClFN3O
|
1
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| 1 |
EC50 = 0.16 nM
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CP0411504
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4-[(3S,3aS)-5,5-difluoro-3-methoxy-3,3a,4,6-tetrahydropyrrolo[1,2-b]pyrazol-2-yl]-2-chloro-3-methylbenzonitrile
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C15H14ClF2N3O
|
1
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| 1 |
EC50 = 0.3 nM
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CP0459784
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4-[(3S,3aS,4R)-4-hydroxy-3-methoxy-3a,4,5,6-tetrahydro-3H-pyrrolo[1,2-b]pyrazol-2-yl]-2-chloro-3-methylbenzonitrile
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|
C15H16ClN3O2
|
1
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| 1 |
EC50 = 0.4 nM
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CP0420073
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2-chloro-4-[[(1R,2R)-2-hydroxy-2-methylcyclopentyl]amino]-3-methylbenzonitrile
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C14H17ClN2O
|
1
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| 1 |
EC50 = 0.499 nM
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|
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CP0053887
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4-[(3S,3aS,4S)-4-hydroxy-3-methoxy-3a,4,5,6-tetrahydro-3H-pyrrolo[1,2-b]pyrazol-2-yl]-2-chloro-3-methylbenzonitrile
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|
C15H16ClN3O2
|
1
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| 1 |
EC50 = 0.5 nM
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CP0255862
|
BMS-564929
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C14H12ClN3O3
|
1
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| 1 |
EC50 = 0.7 nM
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CP0410394
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4-[(3S,3aS,4S)-4-hydroxy-3-(2-methoxyethoxy)-3a,4,5,6-tetrahydro-3H-pyrrolo[1,2-b]pyrazol-2-yl]-2-chloro-3-methylbenzonitrile
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C17H20ClN3O3
|
1
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| 1 |
EC50 = 0.93 nM
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CP0539092
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4-[(3S,3aS,4S)-3-ethoxy-4-hydroxy-3a,4,5,6-tetrahydro-3H-pyrrolo[1,2-b]pyrazol-2-yl]-2-chloro-3-methylbenzonitrile
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|
C16H18ClN3O2
|
1
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| 1 |
EC50 = 1 nM
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CP0379779
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4-[(3S,3aS,5S)-5-fluoro-3-methoxy-3a,4,5,6-tetrahydro-3H-pyrrolo[1,2-b]pyrazol-2-yl]-2-chloro-3-methylbenzonitrile
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|
C15H15ClFN3O
|
1
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| 1 |
EC50 = 1.4 nM
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CP0379780
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4-[(3S,3aR,4S)-4-fluoro-3-methoxy-3a,4,5,6-tetrahydro-3H-pyrrolo[1,2-b]pyrazol-2-yl]-2-chloro-3-methylbenzonitrile
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|
C15H15ClFN3O
|
1
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| 1 |
EC50 = 1.5 nM
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CP0036395
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4-[(1S,7S,7aR)-1-ethyl-7-hydroxy-3-oxo-hexahydro-1H-pyrrolo[1,2-a]imidazolidin-2-yl]-2-chloro-3-methylbenzonitrile
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|
C16H18ClN3O2
|
1
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| 1 |
EC50 = 1.8 nM
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CP0475167
|
4-[(1S,7aR)-1-hydroxy-7-methyl-5-oxo-2,3,5,7a-tetrahydro-1H-pyrrolizin-6-yl]-2-chloro-3-methylbenzonitrile
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|
C16H15ClN2O2
|
1
|
| 1 |
EC50 = 2 nM
|
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CP0522579
|
4-[(1S,7R,7aR)-7-hydroxy-3-oxo-1-(trifluoromethyl)-hexahydro-1H-pyrrolo[1,2-a]imidazolidin-2-yl]-2-chloro-3-methylbenzonitrile
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|
C15H13ClF3N3O2
|
1
|
| 1 |
EC50 = 2.1 nM
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|
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CP0645750
|
(7R,7aS)-4-(tetrahydro-7-hydroxy-1,3-dioxo-1H-pyrrolo[1,2-c]imidazol-2(3H)-yl)-1-naphthalenecarbonitrile
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|
C17H13N3O3
|
1
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| 1 |
EC50 = 2.3 nM
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CP0405803
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4-[(1R,7S,7aR)-7-hydroxy-3-oxo-1-(trifluoromethyl)-hexahydro-1H-pyrrolo[1,2-a]imidazolidin-2-yl]-2-chloro-3-methylbenzonitrile
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|
C15H13ClF3N3O2
|
1
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| 1 |
EC50 = 2.5 nM
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CP0419986
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4-[(1S,7R,7aR)-1-ethyl-7-hydroxy-3-oxo-hexahydro-1H-pyrrolo[1,2-a]imidazolidin-2-yl]-2-chloro-3-methylbenzonitrile
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|
C16H18ClN3O2
|
1
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| 1 |
EC50 = 2.6 nM
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CP0475168
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4-[(1R,7R,7aR)-7-hydroxy-3-oxo-1-(trifluoromethyl)-hexahydro-1H-pyrrolo[1,2-a]imidazolidin-2-yl]-2-chloro-3-methylbenzonitrile
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|
C15H13ClF3N3O2
|
1
|
| 1 |
EC50 = 2.9 nM
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CP0379375
|
4-[(3S,3aS,4S)-4-hydroxy-3-propan-2-yloxy-3a,4,5,6-tetrahydro-3H-pyrrolo[1,2-b]pyrazol-2-yl]-2-chloro-3-methylbenzonitrile
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|
C17H20ClN3O2
|
1
|
| 1 |
EC50 = 4.5 nM
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CP0424851
|
2-chloro-4-[[(1R,2R)-2-hydroxy-2-methylcyclohexyl]amino]-3-methylbenzonitrile
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|
C15H19ClN2O
|
1
|
| 1 |
EC50 = 4.88 nM
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CP0474737
|
4-[(1S,7S,7aR)-7-hydroxy-1-methyl-3-oxo-hexahydro-1H-pyrrolo[1,2-a]imidazolidin-2-yl]-2-chloro-3-methylbenzonitrile
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|
C15H16ClN3O2
|
1
|
| 1 |
EC50 = 5.2 nM
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CP0419987
|
4-[(1R,7S,7aR)-1-ethyl-7-hydroxy-3-oxo-hexahydro-1H-pyrrolo[1,2-a]imidazolidin-2-yl]-2-chloro-3-methylbenzonitrile
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|
C16H18ClN3O2
|
1
|
| 1 |
EC50 = 7.1 nM
|
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CP0555295
|
4-[(3S,3aS,4S)-3,4-dimethoxy-3a,4,5,6-tetrahydro-3H-pyrrolo[1,2-b]pyrazol-2-yl]-2-chloro-3-methylbenzonitrile
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|
C16H18ClN3O2
|
1
|
| 1 |
EC50 = 7.1 nM
|
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CP0419984
|
4-[(1R,7R,7aR)-1-ethyl-7-hydroxy-3-oxo-hexahydro-1H-pyrrolo[1,2-a]imidazolidin-2-yl]-2-chloro-3-methylbenzonitrile
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|
C16H18ClN3O2
|
1
|
| 1 |
EC50 = 7.4 nM
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CP0379782
|
4-[(3S,3aS,5R)-5-hydroxy-3-methoxy-3a,4,5,6-tetrahydro-3H-pyrrolo[1,2-b]pyrazol-2-yl]-2-chloro-3-methylbenzonitrile
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|
C15H16ClN3O2
|
1
|
| 1 |
EC50 = 9.7 nM
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CP0419991
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4-[(1S,7R,7aR)-7-hydroxy-1-methyl-3-oxo-hexahydro-1H-pyrrolo[1,2-a]imidazolidin-2-yl]-2-chloro-3-methylbenzonitrile
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|
C15H16ClN3O2
|
1
|
| 1 |
EC50 = 13 nM
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CP0474544
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4-[(7R,7aR)-7-hydroxy-3-oxo-hexahydro-1H-pyrrolo[1,2-a]imidazolidin-2-yl]-2-chloro-3-methylbenzonitrile
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|
C14H14ClN3O2
|
1
|
| 1 |
EC50 = 15 nM
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CP0465115
|
4-[(3aR,4R,6aS)-4-hydroxy-1-oxo-octahydrocyclopenta[c]pyrrol-2-yl]-2-chloro-3-methylbenzonitrile
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|
C15H15ClN2O2
|
1
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| 1 |
EC50 = 20 nM
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CP0379781
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4-[(3S,3aS)-3-methoxy-5-oxo-3,3a,4,6-tetrahydropyrrolo[1,2-b]pyrazol-2-yl]-2-chloro-3-methylbenzonitrile
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|
C15H14ClN3O2
|
1
|
| 1 |
EC50 = 26 nM
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CP0419990
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4-[(1S,7S,7aR)-7-hydroxy-3-oxo-1-(trifluoromethyl)-hexahydro-1H-pyrrolo[1,2-a]imidazolidin-2-yl]-2-chloro-3-methylbenzonitrile
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|
C15H13ClF3N3O2
|
1
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| 1 |
EC50 = 48 nM
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CP0404345
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2-chloro-4-[[(3R,4S)-4-hydroxy-4-methyloxolan-3-yl]amino]-3-methylbenzonitrile
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C13H15ClN2O2
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1
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| 1 |
EC50 = 73.7 nM
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CP0419992
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4-[(1R,7S,7aR)-7-hydroxy-1-methyl-3-oxo-hexahydro-1H-pyrrolo[1,2-a]imidazolidin-2-yl]-2-chloro-3-methylbenzonitrile
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C15H16ClN3O2
|
1
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| 1 |
EC50 = 87 nM
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CP0405804
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4-[(1R,7R,7aR)-7-hydroxy-3-oxo-1-(propan-2-yl)-hexahydro-1H-pyrrolo[1,2-a]imidazolidin-2-yl]-2-chloro-3-methylbenzonitrile
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C17H20ClN3O2
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1
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| 1 |
EC50 = 108 nM
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CP0494342
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4-[(3S,3aS,4S)-3,4-dihydroxy-3a,4,5,6-tetrahydro-3H-pyrrolo[1,2-b]pyrazol-2-yl]-2-chloro-3-methylbenzonitrile
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|
C14H14ClN3O2
|
1
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| 1 |
EC50 = 978 nM
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