Brief Information of the Compound and Protein
Compound Name
4-[(7R,7aR)-7-hydroxy-3-oxo-hexahydro-1H-pyrrolo[1,2-a]imidazolidin-2-yl]-2-chloro-3-methylbenzonitrile
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PubChem ID
CID: 16733585
SID: 26691757
Canonical SMILES
Cc1c(Cl)c(ccc1N1C[C@@H]2[C@H](O)CCN2C1=O)C#N
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Compound Formula C14H14ClN3O2
Compound Structure
Protein Name
Androgen receptor
Protein Classification
Transcription factor
>
Nuclear receptor
>
Nuclear hormone receptor subfamily 3
>
Nuclear hormone receptor subfamily 3 group C
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Nuclear hormone receptor subfamily 3 group C member 4
Uniprot ID
P10275
Gene Name
AR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000361 C2C12 Mus musculus (Mouse)  1
1
EC50 = 15 nM
   TI
   LI
   LO
   TS
CL000284 MDA-MB-453 Homo sapiens (Human)  2
1
Ki = 2 nM
   TI
   LI
   LO
   TS
2
Ki = 6 nM
   TI
   LI
   LO
   TS