Brief Information of the Cell Line and Protein
Cell Line ID: CL000359 , MDCK-MDR1
 Cell Line Info 
Synonyms
MDCK MDR1
MDCKII-MRP1
MDCKII-MDR1
MDCK2-MDR1
MDCKII x ABCB1-Neo
Category Spontaneously immortalized cell line
Organism
Canis lupus familiaris (Dog)
Cellosaurus ID
CVCL_S586
Protein ID: PT02516 , Multidrug resistance-associated protein 1
 Protein Info 
Gene Name ABCC1
Organism Homo sapiens, Human
Protein Classification Transporter
Uniprot ID P33527
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000359
 Cell Line Info 
 Protein ID: PT02516
 Protein Info 
 
Compound ID Compound Name Compound Formula
CP0426981
 Compound Info 
8-[methyl-[2-[(E)-3-(3,4,5-trimethoxyphenyl)prop-2-enoyl]oxyethyl]amino]octyl 3,4,5-trimethoxybenzoate
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C33H47NO10
  1
1
EC50 = 2200 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0384577
 Compound Info 
3-[methyl-[7-[(E)-3-(3,4,5-trimethoxyphenyl)prop-2-enoyl]oxyheptyl]amino]propyl 3,4,5-trimethoxybenzoate
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C33H47NO10
  1
1
EC50 = 3000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0384580
 Compound Info 
2-[methyl-[8-[(E)-3-(3,4,5-trimethoxyphenyl)prop-2-enoyl]oxyoctyl]amino]ethyl 3,4,5-trimethoxybenzoate
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C33H47NO10
  1
1
EC50 = 4500 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0384576
 Compound Info 
4-[methyl-[6-[(E)-3-(3,4,5-trimethoxyphenyl)prop-2-enoyl]oxyhexyl]amino]butyl 3,4,5-trimethoxybenzoate
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C33H47NO10
  1
1
EC50 = 5080 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0036382
 Compound Info 
CAS_52-53-9
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C27H38N2O4
  1
1
EC50 = 6800 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0386291
 Compound Info 
5-[(4-bromophenyl)methoxy]-N-[2-(5-methoxy-1H-indol-3-yl)ethyl]-4-oxochromene-2-carboxamide
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C28H23BrN2O5
  1
1
IC50 = 3599 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0141589
 Compound Info 
3-((3S,6S)-6-Isobutyl-9-methoxy-1,4-dioxo-1,2,3,4,6,7,12,12a-octahydro-pyrazino[1',2':1,6]pyrido[3,4-b]indol-3-yl)-propionic acid tert-butyl ester
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C26H35N3O5
  1
1
IC50 = 6650 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0490349
 Compound Info 
N-[5-[1-[4-[2-(6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl)ethyl]phenyl]triazol-4-yl]-2-(2-methylpropanoyl)phenyl]quinoline-2-carboxamide
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C41H40N6O4
  1
1
IC50 >= 19040 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0530501
 Compound Info 
(Z)-2-(3,4-dimethoxyphenyl)-3-[5-(4-hydroxypiperidin-1-yl)thiophen-2-yl]prop-2-enenitrile
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C20H22N2O3S
  1
1
IC50 >= 39750 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS