Brief Information of the Cell Line and Protein
Cell Line ID: CL000358 , NCI-H69
Synonyms
NCI-H-69
NCI H69
H69
H-69
NCIH69
NCI-HUT-69
H69/P
NCI-H69C
H69C
H69c
Category Cancer cell line
Organism
Homo sapiens (Human)
Cellosaurus ID
CVCL_1579
Protein ID: PT02516 , Multidrug resistance-associated protein 1
Gene Name ABCC1
Organism Homo sapiens, Human
Protein Classification Transporter
Uniprot ID P33527
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000358  Protein ID: PT02516
 
Compound ID Compound Name Compound Formula
CP0498621
2-methoxyethyl 3-amino-2-(4-methoxybenzoyl)-6-methyl-4-(3,4,5-trimethoxyphenyl)thieno[2,3-b]pyridine-5-carboxylate
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C29H30N2O8S
 1
1
EC50 = 1100 nM
   TI
   LI
   LO
   TS
CP0397065
2-methoxyethyl 3-amino-2-benzoyl-6-methyl-4-(3,4,5-trimethoxyphenyl)thieno[2,3-b]pyridine-5-carboxylate
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C28H28N2O7S
 1
1
EC50 = 3900 nM
   TI
   LI
   LO
   TS
CP0396959
ethyl 3-amino-2-benzoyl-6-methyl-4-(3,4,5-trimethoxyphenyl)thieno[2,3-b]pyridine-5-carboxylate
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C27H26N2O6S
 1
1
EC50 = 5200 nM
   TI
   LI
   LO
   TS
CP0411410
ethyl 3-amino-2-(4-methoxybenzoyl)-6-methyl-4-(3,4,5-trimethoxyphenyl)thieno[2,3-b]pyridine-5-carboxylate
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C28H28N2O7S
 1
1
EC50 = 5200 nM
   TI
   LI
   LO
   TS
CP0396977
1-[3-amino-2-(4-methoxybenzoyl)-6-methyl-4-(3,4,5-trimethoxyphenyl)thieno[2,3-b]pyridin-5-yl]ethanone
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C27H26N2O6S
 1
1
EC50 = 6600 nM
   TI
   LI
   LO
   TS
CP0396961
2-methoxyethyl 3-amino-2-(2,4-dimethoxybenzoyl)-6-methyl-4-(3,4,5-trimethoxyphenyl)thieno[2,3-b]pyridine-5-carboxylate
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C30H32N2O9S
 1
1
EC50 = 7000 nM
   TI
   LI
   LO
   TS
CP0462999
N-(3-morpholin-4-ylpropyl)-5,7-diphenylpyrazolo[1,5-a]pyrimidine-3-carboxamide
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C26H27N5O2
 1
1
EC50 = 9800 nM
   TI
   LI
   LO
   TS
CP0415243
methyl 3-amino-4-(3,4-dimethoxyphenyl)-2-(4-methoxybenzoyl)-6-methylthieno[2,3-b]pyridine-5-carboxylate
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C26H24N2O6S
 1
1
EC50 = 11900 nM
   TI
   LI
   LO
   TS
CP0078757
(E)-3-((3-(2-(7-chloroquinolin-2-yl)vinyl)phenyl)(3-(dimethylamino)-3-oxopropylthio)methylthio)propanoic acid
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C26H27ClN2O3S2
 1
1
EC50 = 12400 nM
   TI
   LI
   LO
   TS
CP0415247
ethyl 3-amino-2-(2,4-dimethoxybenzoyl)-6-methyl-4-(3,4,5-trimethoxyphenyl)thieno[2,3-b]pyridine-5-carboxylate
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C29H30N2O8S
 1
1
EC50 = 12400 nM
   TI
   LI
   LO
   TS
CP0036382
CAS_52-53-9
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C27H38N2O4
 1
1
EC50 = 27800 nM
   TI
   LI
   LO
   TS
CP0562213
methyl 3-amino-2-(2,4-dimethoxybenzoyl)-4-(3,4-dimethoxyphenyl)-6-methylthieno[2,3-b]pyridine-5-carboxylate
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C27H26N2O7S
 1
1
EC50 = 41400 nM
   TI
   LI
   LO
   TS