| Compound ID |
Compound Name |
Compound Formula |
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CP0070809
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CCI-18781
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C25H31F3O5S
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1
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| 1 |
EC50 = 0.76 nM
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CP0393622
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[(8S,9S,10R,11S,13S,14S,17R)-17-[2-(1,3-benzothiazol-2-ylsulfanyl)acetyl]-11-hydroxy-10,13-dimethyl-3-oxo-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-17-yl] furan-2-carboxylate
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C33H33NO6S2
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1
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| 1 |
EC50 = 18.7 nM
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CP0238565
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(6S,8S,9R,10S,11S,13S,14S,16R,17R)-17-[2-(1,3-benzothiazol-2-ylsulfanyl)acetyl]-6,9-difluoro-11,17-dihydroxy-10,13,16-trimethyl-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-3-one
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C29H31F2NO4S2
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1
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| 1 |
EC50 = 27 nM
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CP0035186
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(10S,11S,14S,15S,17R)-17-[4-(dimethylamino)phenyl]-14-hydroxy-15-methyl-14-(prop-1-yn-1-yl)tetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadeca-1,6-dien-5-one
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C29H35NO2
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1
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| 1 |
IC50 = 1.94 nM
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CP0416607
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1-[(1S,2R,13S,14S,17R,18S,20S)-7-(4-fluorophenyl)-17,20-dihydroxy-2,18-dimethyl-6,7-diazapentacyclo[11.7.0.02,10.04,8.014,18]icosa-4(8),5,9-trien-17-yl]-2-hydroxyethanone
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C28H33FN2O4
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1
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| 1 |
IC50 = 3.2 nM
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CP0416614
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1-[(1S,2R,13S,14S,17R,18S,20S)-17,20-dihydroxy-2,18-dimethyl-7-phenyl-6,7-diazapentacyclo[11.7.0.02,10.04,8.014,18]icosa-4(8),5,9-trien-17-yl]-2-hydroxyethanone
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C28H34N2O4
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1
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| 1 |
IC50 = 3.23 nM
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CP0380981
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1-[(1S,2R,13S,14S,17R,18S,20S)-7-(4-fluorophenyl)-17,20-dihydroxy-2,18-dimethyl-6,7-diazapentacyclo[11.7.0.02,10.04,8.014,18]icosa-4(8),5,9-trien-17-yl]-2-pyridin-2-ylsulfanylethanone
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C33H36FN3O3S
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1
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| 1 |
IC50 = 4.5 nM
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CP0444548
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N-[2-[[benzyl(methyl)amino]methyl]-3-(4-fluoro-2-methoxyphenyl)-5-propan-2-yl-1H-indol-7-yl]methanesulfonamide
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C28H32FN3O3S
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1
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| 1 |
IC50 = 10.6 nM
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CP0400170
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1-[(1S,2R,13S,14S,17R,18S,20S)-7-(4-fluorophenyl)-17,20-dihydroxy-2,18-dimethyl-6,7-diazapentacyclo[11.7.0.02,10.04,8.014,18]icosa-4(8),5,9-trien-17-yl]-2-([1,3]oxazolo[4,5-b]pyridin-2-ylsulfanyl)ethanone
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C34H35FN4O4S
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1
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| 1 |
IC50 = 13.3 nM
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CP0416609
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1-[(1S,2R,13S,14S,17R,18S,20S)-7-(4-fluorophenyl)-17,20-dihydroxy-2,18-dimethyl-6,7-diazapentacyclo[11.7.0.02,10.04,8.014,18]icosa-4(8),5,9-trien-17-yl]-2-pyrimidin-2-ylsulfanylethanone
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C32H35FN4O3S
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1
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| 1 |
IC50 = 14.3 nM
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CP0410986
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N-[2-[[benzyl(methyl)amino]methyl]-5-tert-butyl-3-(4-fluoro-2-methoxyphenyl)-1H-indol-7-yl]methanesulfonamide
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C29H34FN3O3S
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1
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| 1 |
IC50 = 14.4 nM
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CP0387981
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(8S,9S,10R,11S,13S,14S,16R,17R)-11,17-dihydroxy-10,13,16-trimethyl-17-(2-quinolin-2-ylsulfanylacetyl)-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-3-one
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C31H35NO4S
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1
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| 1 |
IC50 = 19.2 nM
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CP0432716
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(8S,9S,10R,11S,13S,14S,16R,17R)-11,17-dihydroxy-10,13,16-trimethyl-17-[2-([1,3]thiazolo[5,4-b]pyridin-2-ylsulfanyl)acetyl]-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-3-one
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C28H32N2O4S2
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1
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| 1 |
IC50 = 24.1 nM
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CP0400172
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2-(1,3-benzothiazol-2-ylsulfanyl)-1-[(1S,2R,13S,14S,17R,18S,20S)-7-(4-fluorophenyl)-17,20-dihydroxy-2,18-dimethyl-6,7-diazapentacyclo[11.7.0.02,10.04,8.014,18]icosa-4(8),5,9-trien-17-yl]ethanone
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C35H36FN3O3S2
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1
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| 1 |
IC50 = 24.1 nM
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CP0400173
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1-[(1S,2R,13S,14S,17R,18S,20S)-7-(4-fluorophenyl)-17,20-dihydroxy-2,18-dimethyl-6,7-diazapentacyclo[11.7.0.02,10.04,8.014,18]icosa-4(8),5,9-trien-17-yl]-2-quinolin-2-ylsulfanylethanone
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C37H38FN3O3S
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1
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| 1 |
IC50 = 24.3 nM
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CP0428604
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2-(1,3-benzoxazol-2-ylsulfanyl)-1-[(1S,2R,13S,14S,17R,18S,20S)-7-cyclohexyl-17,20-dihydroxy-2,18-dimethyl-6,7-diazapentacyclo[11.7.0.02,10.04,8.014,18]icosa-4(8),5,9-trien-17-yl]ethanone
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C35H43N3O4S
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1
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| 1 |
IC50 = 31.6 nM
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CP0400175
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1-[(1S,2R,13S,14S,17R,18S,20S)-17,20-dihydroxy-2,18-dimethyl-7-phenyl-6,7-diazapentacyclo[11.7.0.02,10.04,8.014,18]icosa-4(8),5,9-trien-17-yl]-2-([1,3]oxazolo[4,5-b]pyridin-2-ylsulfanyl)ethanone
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C34H36N4O4S
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1
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| 1 |
IC50 = 33.8 nM
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CP0432419
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1-[(1S,2R,13S,14S,17R,18S,20S)-7-(4-fluorophenyl)-17,20-dihydroxy-2,18-dimethyl-6,7-diazapentacyclo[11.7.0.02,10.04,8.014,18]icosa-4(8),5,9-trien-17-yl]-2-quinolin-2-yloxyethanone
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C37H38FN3O4
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1
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| 1 |
IC50 = 44.7 nM
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CP0400160
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1-[(1S,2R,13S,14S,17R,18S,20S)-7-(4-fluorophenyl)-17,20-dihydroxy-2,18-dimethyl-6,7-diazapentacyclo[11.7.0.02,10.04,8.014,18]icosa-4(8),5,9-trien-17-yl]-2-naphthalen-2-ylsulfanylethanone
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C38H39FN2O3S
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1
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| 1 |
IC50 = 52.5 nM
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CP0400171
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2-(1,3-benzothiazol-2-ylsulfanyl)-1-[(1S,2R,13S,14S,17R,18S,20S)-7-cyclohexyl-17,20-dihydroxy-2,18-dimethyl-6,7-diazapentacyclo[11.7.0.02,10.04,8.014,18]icosa-4(8),5,9-trien-17-yl]ethanone
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C35H43N3O3S2
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1
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| 1 |
IC50 = 54.7 nM
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CP0380940
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2-(1,3-benzothiazol-2-ylsulfanyl)-1-[(1S,2R,13S,14S,17R,18S,20S)-17,20-dihydroxy-2,18-dimethyl-7-phenyl-6,7-diazapentacyclo[11.7.0.02,10.04,8.014,18]icosa-4(8),5,9-trien-17-yl]ethanone
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C35H37N3O3S2
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1
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| 1 |
IC50 = 57.3 nM
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CP0416608
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1-[(1S,2R,13S,14S,17R,18S,20S)-7-(4-fluorophenyl)-17,20-dihydroxy-2,18-dimethyl-6,7-diazapentacyclo[11.7.0.02,10.04,8.014,18]icosa-4(8),5,9-trien-17-yl]-2-naphthalen-2-yloxyethanone
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C38H39FN2O4
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1
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| 1 |
IC50 = 58 nM
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CP0413727
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N-[5-fluoro-3-(4-fluoro-2-methoxyphenyl)-2-methyl-1H-indol-7-yl]methanesulfonamide
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C17H16F2N2O3S
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1
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| 1 |
IC50 = 63.4 nM
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CP0047174
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(1S,2R,10S,11S,14R,15S,17S)-14,17-dihydroxy-14-(2-hydroxyacetyl)-2,15-dimethyltetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadeca-3,6-dien-5-one
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C21H28O5
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1
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| 1 |
IC50 = 65.4 nM
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CP0380980
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1-[(1S,2R,13S,14S,17R,18S,20S)-7-(4-fluorophenyl)-17,20-dihydroxy-2,18-dimethyl-6,7-diazapentacyclo[11.7.0.02,10.04,8.014,18]icosa-4(8),5,9-trien-17-yl]-2-isoquinolin-1-ylsulfanylethanone
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C37H38FN3O3S
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1
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| 1 |
IC50 = 65.4 nM
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CP0413728
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N-[3-(3-chlorophenyl)-1H-indol-7-yl]methanesulfonamide
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C15H13ClN2O2S
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1
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| 1 |
IC50 = 76 nM
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CP0410217
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1-[(1S,2R,13S,14S,17R,18S,20S)-17,20-dihydroxy-2,18-dimethyl-7-phenyl-6,7-diazapentacyclo[11.7.0.02,10.04,8.014,18]icosa-4(8),5,9-trien-17-yl]-2-(1-methylbenzimidazol-2-yl)sulfanylethanone
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C36H40N4O3S
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1
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| 1 |
IC50 = 78 nM
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CP0416612
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1-[(1S,2R,13S,14S,17R,18S,20S)-7-(4-fluorophenyl)-17,20-dihydroxy-2,18-dimethyl-6,7-diazapentacyclo[11.7.0.02,10.04,8.014,18]icosa-4(8),5,9-trien-17-yl]-2-(1-methylbenzimidazol-2-yl)oxyethanone
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C36H39FN4O4
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1
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| 1 |
IC50 = 78 nM
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CP0400177
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1-[(1S,2R,13S,14S,17R,18S,20S)-17,20-dihydroxy-2,18-dimethyl-7-phenyl-6,7-diazapentacyclo[11.7.0.02,10.04,8.014,18]icosa-4(8),5,9-trien-17-yl]-2-quinolin-2-ylsulfanylethanone
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C37H39N3O3S
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1
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| 1 |
IC50 = 82.3 nM
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CP0385331
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2-(1,3-benzothiazol-2-yloxy)-1-[(1S,2R,13S,14S,17R,18S,20S)-7-(4-fluorophenyl)-17,20-dihydroxy-2,18-dimethyl-6,7-diazapentacyclo[11.7.0.02,10.04,8.014,18]icosa-4(8),5,9-trien-17-yl]ethanone
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C35H36FN3O4S
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1
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| 1 |
IC50 = 84 nM
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CP0385328
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2-[2-[(1S,2R,13S,14S,17R,18S,20S)-7-(4-fluorophenyl)-17,20-dihydroxy-2,18-dimethyl-6,7-diazapentacyclo[11.7.0.02,10.04,8.014,18]icosa-4(8),5,9-trien-17-yl]-2-oxoethyl]sulfanyl-3H-quinazolin-4-one
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C36H37FN4O4S
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1
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| 1 |
IC50 = 86.5 nM
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CP0416610
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1-[(1S,2R,13S,14S,17R,18S,20S)-17,20-dihydroxy-2,18-dimethyl-7-phenyl-6,7-diazapentacyclo[11.7.0.02,10.04,8.014,18]icosa-4(8),5,9-trien-17-yl]-2-quinoxalin-2-ylsulfanylethanone
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C36H38N4O3S
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1
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| 1 |
IC50 = 113 nM
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CP0401463
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(8S,9S,10R,11S,13S,14S,16R,17R)-11,17-dihydroxy-10,13,16-trimethyl-17-[2-([1,3]oxazolo[4,5-b]pyridin-2-ylsulfanyl)acetyl]-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-3-one
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C28H32N2O5S
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1
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| 1 |
IC50 = 135 nM
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CP0446952
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1-[(1S,2R,13S,14S,17R,18S,20S)-7-cyclohexyl-17,20-dihydroxy-2,18-dimethyl-6,7-diazapentacyclo[11.7.0.02,10.04,8.014,18]icosa-4(8),5,9-trien-17-yl]-2-[(4,5-dimethyl-1,3-thiazol-2-yl)sulfanyl]ethanone
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C33H45N3O3S2
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1
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| 1 |
IC50 = 135 nM
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CP0410216
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1-[(1S,2R,13S,14S,17R,18S,20S)-7-(4-fluorophenyl)-17,20-dihydroxy-2,18-dimethyl-6,7-diazapentacyclo[11.7.0.02,10.04,8.014,18]icosa-4(8),5,9-trien-17-yl]-2-(1-methylbenzimidazol-2-yl)sulfanylethanone
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C36H39FN4O3S
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1
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| 1 |
IC50 = 174 nM
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CP0400174
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1-[(1S,2R,13S,14S,17R,18S,20S)-17,20-dihydroxy-2,18-dimethyl-7-phenyl-6,7-diazapentacyclo[11.7.0.02,10.04,8.014,18]icosa-4(8),5,9-trien-17-yl]-2-pyridin-2-ylsulfanylethanone
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C33H37N3O3S
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1
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| 1 |
IC50 = 225 nM
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CP0387984
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(8S,9S,10R,11S,13S,14S,16R,17R)-17-[2-(1,3-benzothiazol-2-ylsulfanyl)acetyl]-11,17-dihydroxy-10,13,16-trimethyl-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-3-one
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C29H33NO4S2
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1
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| 1 |
IC50 = 230 nM
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CP0145473
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(8S,9S,10R,11S,13S,14S,17R)-11,17-dihydroxy-10,13-dimethyl-17-[2-(1-methylbenzimidazol-2-yl)sulfanylacetyl]-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-3-one
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C29H34N2O4S
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1
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| 1 |
IC50 = 235 nM
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CP0434913
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1-[(1S,2R,13S,14S,17R,18S,20S)-17,20-dihydroxy-2,18-dimethyl-7-phenyl-6,7-diazapentacyclo[11.7.0.02,10.04,8.014,18]icosa-4(8),5,9-trien-17-yl]-2-(1-prop-2-enylbenzimidazol-2-yl)sulfanylethanone
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C38H42N4O3S
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1
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| 1 |
IC50 = 258 nM
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CP0429171
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N-[2-benzyl-3-(4-fluoro-2-methoxyphenyl)-5-propan-2-yl-1H-indol-7-yl]methanesulfonamide
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C26H27FN2O3S
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1
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| 1 |
IC50 = 292 nM
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CP0385432
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(8S,9S,10R,11S,13S,14S,17R)-11,17-dihydroxy-10,13-dimethyl-17-(2-quinolin-2-ylsulfanylacetyl)-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-3-one
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C30H33NO4S
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1
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| 1 |
IC50 = 361 nM
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CP0385431
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(8S,9S,10R,11S,13S,14S,17R)-11,17-dihydroxy-10,13-dimethyl-17-(2-pyridin-2-ylsulfanylacetyl)-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-3-one
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C26H31NO4S
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1
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| 1 |
IC50 = 707 nM
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CP0427353
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(8S,9S,10R,11S,13S,14S,16R,17R)-11,17-dihydroxy-10,13,16-trimethyl-17-[2-[(5-phenyl-1,3,4-oxadiazol-2-yl)sulfanyl]acetyl]-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-3-one
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C30H34N2O5S
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1
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| 1 |
IC50 = 740 nM
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CP0409039
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1-[(1S,2R,13S,14S,17R,18S,20S)-7-cyclohexyl-17,20-dihydroxy-2,18-dimethyl-6,7-diazapentacyclo[11.7.0.02,10.04,8.014,18]icosa-4(8),5,9-trien-17-yl]-2-(1-methylbenzimidazol-2-yl)sulfanylethanone
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C36H46N4O3S
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1
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| 1 |
IC50 = 1000 nM
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CP0513116
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N-[3-(2-methoxyphenyl)-1H-indol-7-yl]methanesulfonamide
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C16H16N2O3S
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1
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| 1 |
IC50 = 1180 nM
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CP0416932
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N-[3-(5-chloro-2-methoxyphenyl)-1H-indol-7-yl]methanesulfonamide
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C16H15ClN2O3S
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1
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| 1 |
IC50 = 1250 nM
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CP0424441
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2-[3,5-dibromo-4-[4-methoxy-2-(3-methylbenzoyl)-5-propan-2-ylphenoxy]phenyl]acetic acid
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C26H24Br2O5
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1
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| 1 |
IC50 = 2500 nM
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