Brief Information of the Compound and Protein
Compound Name
 Compound Info 
1-[(1S,2R,13S,14S,17R,18S,20S)-7-cyclohexyl-17,20-dihydroxy-2,18-dimethyl-6,7-diazapentacyclo[11.7.0.02,10.04,8.014,18]icosa-4(8),5,9-trien-17-yl]-2-[(4,5-dimethyl-1,3-thiazol-2-yl)sulfanyl]ethanone
    Show/Hide
 PubChem ID
CID: 70691920
Canonical SMILES
Cc1nc(SCC(=O)[C@@]2(O)CC[C@H]3[C@@H]4CCC5=Cc6c(C[C@]5(C)[C@H]4[C@@H](O)C[C@]23C)cnn6C2CCCCC2)sc1C
    Show/Hide
Compound Formula C33H45N3O3S2
Compound Structure
Protein Name
 Protein Info 
Glucocorticoid receptor
Protein Classification
Transcription factor
>
Nuclear receptor
>
Nuclear hormone receptor subfamily 3
>
Nuclear hormone receptor subfamily 3 group C
>
Nuclear hormone receptor subfamily 3 group C member 1
Uniprot ID
P06536
Gene Name
NR3C1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000298 H4-II-E
 Cell Line Info 
Rattus norvegicus (Rat)  1
1
IC50 = 135 nM
   TI
   LI
   LO
   TS