Brief Information of the Cell Line and Protein
Cell Line ID: CL000247 , MT-4
Synonyms
MT4
Category Transformed cell line
Organism
Homo sapiens (Human)
Cellosaurus ID
CVCL_2632
Protein ID: PT02533 , Histone-arginine methyltransferase CARM1
Gene Name CARM1
Organism Homo sapiens, Human
Protein Classification Epigenetic regulator
Uniprot ID Q86X55
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000247  Protein ID: PT02533
 
Compound ID Compound Name Compound Formula
CP0541525
2-[4-[(2-bromophenyl)methoxy]piperidin-1-yl]-N-methylethanamine
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C15H23BrN2O
 1
1
IC50 = 14 nM
   TI
   LI
   LO
   TS
CP0374557
2-[4-[[4-(3,5-dimethylpyrazol-1-yl)phenyl]methoxy]piperidin-1-yl]-N-methylethanamine
   Show/Hide
C20H30N4O
 1
1
IC50 = 15 nM
   TI
   LI
   LO
   TS
CP0541524
2-[4-[(4-bromophenyl)methoxy]piperidin-1-yl]-N-methylethanamine
   Show/Hide
C15H23BrN2O
 1
1
IC50 = 15 nM
   TI
   LI
   LO
   TS
CP0481795
N-methyl-2-[4-[[4-(2-methylbutan-2-yl)phenyl]methoxy]piperidin-1-yl]ethanamine
   Show/Hide
C20H34N2O
 1
1
IC50 = 16 nM
   TI
   LI
   LO
   TS
CP0399538
2-[4-[(3-bromophenyl)methoxy]piperidin-1-yl]-N-methylethanamine
   Show/Hide
C15H23BrN2O
 1
1
IC50 = 17 nM
   TI
   LI
   LO
   TS
CP0525534
N-methyl-2-[4-[(4-phenylphenyl)methoxy]piperidin-1-yl]ethanamine
   Show/Hide
C21H28N2O
 1
1
IC50 = 17 nM
   TI
   LI
   LO
   TS
CP0374533
2-[4-[(4-chlorophenyl)methoxy]piperidin-1-yl]-N-methylethanamine
   Show/Hide
C15H23ClN2O
 1
1
IC50 = 18 nM
   TI
   LI
   LO
   TS
CP0542382
2-[4-[(2-chlorophenyl)methoxy]piperidin-1-yl]-N-methylethanamine
   Show/Hide
C15H23ClN2O
 1
1
IC50 = 18 nM
   TI
   LI
   LO
   TS
CP0565918
2-[4-[(4-fluorophenyl)methoxy]piperidin-1-yl]-N-methylethanamine
   Show/Hide
C15H23FN2O
 1
1
IC50 = 19 nM
   TI
   LI
   LO
   TS
CP0481794
2-[4-[[4-(2,3-dichlorophenoxy)phenyl]methoxy]piperidin-1-yl]-N-methylethanamine
   Show/Hide
C21H26Cl2N2O2
 1
1
IC50 = 22 nM
   TI
   LI
   LO
   TS
CP0540322
N-methyl-2-[4-[[2-(trifluoromethyl)phenyl]methoxy]piperidin-1-yl]ethanamine
   Show/Hide
C16H23F3N2O
 1
1
IC50 = 23 nM
   TI
   LI
   LO
   TS
CP0040875
N-methyl-2-[4-[(3-phenylphenyl)methoxy]piperidin-1-yl]ethanamine
   Show/Hide
C21H28N2O
 1
1
IC50 = 27 nM
   TI
   LI
   LO
   TS
CP0380035
N-methyl-2-[4-[[3-(trifluoromethyl)phenyl]methoxy]piperidin-1-yl]ethanamine
   Show/Hide
C16H23F3N2O
 1
1
IC50 = 28 nM
   TI
   LI
   LO
   TS
CP0415388
N-methyl-2-[4-[[4-(trifluoromethoxy)phenyl]methoxy]piperidin-1-yl]ethanamine
   Show/Hide
C16H23F3N2O2
 1
1
IC50 = 28 nM
   TI
   LI
   LO
   TS
CP0540323
2-[4-[(3-chlorophenyl)methoxy]piperidin-1-yl]-N-methylethanamine
   Show/Hide
C15H23ClN2O
 1
1
IC50 = 33 nM
   TI
   LI
   LO
   TS
CP0021188
N-methyl-2-(4-phenylmethoxypiperidin-1-yl)ethanamine
   Show/Hide
C15H24N2O
 1
1
IC50 = 34 nM
   TI
   LI
   LO
   TS
CP0540324
2-[4-[(2-fluorophenyl)methoxy]piperidin-1-yl]-N-methylethanamine
   Show/Hide
C15H23FN2O
 1
1
IC50 = 35 nM
   TI
   LI
   LO
   TS
CP0040876
2-[4-[(3-fluorophenyl)methoxy]piperidin-1-yl]-N-methylethanamine
   Show/Hide
C15H23FN2O
 1
1
IC50 = 41 nM
   TI
   LI
   LO
   TS
CP0540321
N-methyl-2-[4-[(2-phenylphenyl)methoxy]piperidin-1-yl]ethanamine
   Show/Hide
C21H28N2O
 1
1
IC50 = 41 nM
   TI
   LI
   LO
   TS
CP0520624
2-[4-[(4-cyclohexylphenyl)methoxy]piperidin-1-yl]-N-methylethanamine
   Show/Hide
C21H34N2O
 1
1
IC50 = 42 nM
   TI
   LI
   LO
   TS
CP0471249
N-methyl-2-[4-[[4-(2,2,2-trifluoroethoxy)phenyl]methoxy]piperidin-1-yl]ethanamine
   Show/Hide
C17H25F3N2O2
 1
1
IC50 = 53 nM
   TI
   LI
   LO
   TS
CP0374531
N-methyl-2-[4-[[4-(trifluoromethyl)phenyl]methoxy]piperidin-1-yl]ethanamine
   Show/Hide
C16H23F3N2O
 1
1
IC50 = 62 nM
   TI
   LI
   LO
   TS
CP0565921
2-(3-benzylpyrrolidin-1-yl)-N-methylethanamine
   Show/Hide
C14H22N2
 1
1
IC50 = 80 nM
   TI
   LI
   LO
   TS
CP0573495
N-methyl-2-[4-[[4-(2-methylpropyl)phenyl]methoxy]piperidin-1-yl]ethanamine
   Show/Hide
C19H32N2O
 1
1
IC50 = 85 nM
   TI
   LI
   LO
   TS
CP0431415
N-methyl-2-[4-(phenoxymethyl)piperidin-1-yl]ethanamine
   Show/Hide
C15H24N2O
 1
1
IC50 = 98 nM
   TI
   LI
   LO
   TS
CP0465155
N-[[1-[2-(methylamino)ethyl]piperidin-4-yl]methyl]aniline
   Show/Hide
C15H25N3
 1
1
IC50 = 103 nM
   TI
   LI
   LO
   TS
CP0442811
N-methyl-2-[4-(2-phenylethyl)piperidin-1-yl]ethanamine
   Show/Hide
C16H26N2
 1
1
IC50 = 108 nM
   TI
   LI
   LO
   TS
CP0410060
2-(3-benzylpiperidin-1-yl)-N-methylethanamine
   Show/Hide
C15H24N2
 1
1
IC50 = 120 nM
   TI
   LI
   LO
   TS
CP0520602
N-methyl-2-(4-phenoxypiperidin-1-yl)ethanamine
   Show/Hide
C14H22N2O
 1
1
IC50 = 149 nM
   TI
   LI
   LO
   TS
CP0539693
[1-[2-(methylamino)ethyl]piperidin-4-yl] benzoate
   Show/Hide
C15H22N2O2
 1
1
IC50 = 177 nM
   TI
   LI
   LO
   TS
CP0565919
N-[1-[2-(methylamino)ethyl]piperidin-4-yl]benzamide
   Show/Hide
C15H23N3O
 1
1
IC50 = 231 nM
   TI
   LI
   LO
   TS
CP0481813
1-[2-(methylamino)ethyl]-N-phenylpiperidin-4-amine
   Show/Hide
C14H23N3
 1
1
IC50 = 616 nM
   TI
   LI
   LO
   TS
CP0465156
2-(4-benzylpiperidin-1-yl)-N-methylethanamine
   Show/Hide
C15H24N2
 1
1
IC50 = 890 nM
   TI
   LI
   LO
   TS
CP0465154
[1-[2-(methylamino)ethyl]piperidin-4-yl]methyl benzoate
   Show/Hide
C16H24N2O2
 1
1
IC50 = 1070 nM
   TI
   LI
   LO
   TS
CP0406361
1-(4-benzylpiperidin-1-yl)-3-(methylamino)propan-2-ol
   Show/Hide
C16H26N2O
 1
1
IC50 = 1220 nM
   TI
   LI
   LO
   TS
CP0431414
1-[2-(methylamino)ethyl]-N-phenylpiperidine-4-carboxamide
   Show/Hide
C15H23N3O
 1
1
IC50 = 1540 nM
   TI
   LI
   LO
   TS
CP0431416
[1-[2-(methylamino)ethyl]piperidin-4-yl]-phenylmethanol
   Show/Hide
C15H24N2O
 1
1
IC50 = 1637 nM
   TI
   LI
   LO
   TS
CP0541526
N-methyl-2-(4-phenylsulfanylpiperidin-1-yl)ethanamine
   Show/Hide
C14H22N2S
 1
1
IC50 = 3680 nM
   TI
   LI
   LO
   TS
CP0565920
N-methyl-2-(4-phenylpiperidin-1-yl)ethanamine
   Show/Hide
C14H22N2
 1
1
IC50 = 6250 nM
   TI
   LI
   LO
   TS
CP0540325
3-(4-benzylpiperidin-1-yl)-N-methylpropan-1-amine
   Show/Hide
C16H26N2
 1
1
IC50 > 10000 nM
   TI
   LI
   LO
   TS
CP0431417
2-(4-benzylpiperidin-1-yl)-N-ethylethanamine
   Show/Hide
C16H26N2
 1
1
IC50 > 4700 nM
   TI
   LI
   LO
   TS