Brief Information of the Cell Line and Protein
Cell Line ID: CL000244 , 786-O
 Cell Line Info 
Synonyms
786-o
786O
786-0
786.O
786-O RCC
RCC 786-O
RCC_7860
RCC 7860
7860
786-0WT
Category Cancer cell line
Organism
Homo sapiens (Human)
Cellosaurus ID
CVCL_1051
Protein ID: PT01033 , Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform
 Protein Info 
Gene Name PIK3CB
Organism Homo sapiens, Human
Protein Classification Enzyme
Uniprot ID P42338
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000244
 Cell Line Info 
 Protein ID: PT01033
 Protein Info 
 
Compound ID Compound Name Compound Formula
CP0010347
 Compound Info 
GSK-2636771
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C22H22F3N3O3
  1
1
IC50 = 48 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0219705
 Compound Info 
2-amino-4-[[(1S)-1-[7-fluoro-1-(4-fluorophenyl)-4-oxo-3-phenylquinolizin-2-yl]ethyl]amino]-6-methylpyrimidine-5-carbonitrile
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C29H22F2N6O
  1
1
IC50 = 78 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0353655
 Compound Info 
4-amino-6-[[(1S)-1-(6-methyl-4-oxo-3-phenylquinolizin-2-yl)ethyl]amino]pyrimidine-5-carbonitrile
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C23H20N6O
  1
1
IC50 = 134 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0702721
 Compound Info 
(S)-2-(1-((9H-Purin-6-yl)amino)ethyl)-7-fluoro-3-phenyl-4H-quinolizin-4-one
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C22H17FN6O
  1
1
IC50 = 191 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0176936
 Compound Info 
2,4-diamino-6-[[(1S)-1-[7-fluoro-1-(4-fluorophenyl)-4-oxo-3-phenylquinolizin-2-yl]ethyl]amino]pyrimidine-5-carbonitrile
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C28H21F2N7O
  1
1
IC50 = 208 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0006058
 Compound Info 
2-amino-N-[(1S)-1-[8-[2-(1-methylpyrazol-4-yl)ethynyl]-1-oxo-2-phenylisoquinolin-3-yl]ethyl]pyrazolo[1,5-a]pyrimidine-3-carboxamide
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C30H24N8O2
  1
1
IC50 = 240 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0136524
 Compound Info 
2,4-diamino-6-[[(1S)-1-(7-fluoro-4-oxo-3-phenylquinolizin-2-yl)ethyl]amino]pyrimidine-5-carbonitrile
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C22H18FN7O
  1
1
IC50 = 241 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0952933
 Compound Info 
(S)-2-(1-((9H-Purin-6-yl)amino)ethyl)-6-methyl-3-phenyl-4H-quinolizin-4-one
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C23H20N6O
  1
1
IC50 = 515 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS