Brief Information of the Compound and Protein
Compound Name
 Compound Info 
GSK-2636771
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 PubChem ID
CID: 56949517
SID: 135656208
Canonical SMILES
Cc1nc2c(cc(cc2n1Cc1cccc(c1C)C(F)(F)F)N1CCOCC1)C(O)=O
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Compound Formula C22H22F3N3O3
Compound Structure
Protein Name
 Protein Info 
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform
Protein Classification
Enzyme
>
Transferase
Uniprot ID
P42338
Gene Name
PIK3CB
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000244 786-O
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 48 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 0.89 nM
2 IC50 = 21.7 nM