Brief Information of the Cell Line and Protein
Cell Line ID: CL000243 , MCF-10A
 Cell Line Info 
Synonyms
MCF 10A
MCF.10A
MCF10A
MCF10-A
MCF10a
MCF-10 Attached
Michigan Cancer Foundation-10A
Category Spontaneously immortalized cell line
Organism
Homo sapiens (Human)
Cellosaurus ID
CVCL_0598
Protein ID: PT03005 , Serine protease hepsin
 Protein Info 
Gene Name HPN
Organism Homo sapiens, Human
Protein Classification Enzyme
Uniprot ID P05981
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000243
 Cell Line Info 
 Protein ID: PT03005
 Protein Info 
 
Compound ID Compound Name Compound Formula
CP0065004
 Compound Info 
(2R)-N-(4-carbamimidoylphenyl)-2-[(4-methylphenyl)sulfonylamino]-2-phenylacetamide
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C22H22N4O3S
  1
1
IC50 = 100 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0064994
 Compound Info 
(2R)-N-(4-carbamimidoylphenyl)-2-cyclohexyl-2-[(4-methylphenyl)sulfonylamino]acetamide
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C22H28N4O3S
  1
1
IC50 = 990 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0099151
 Compound Info 
(2R)-N-(4-carbamimidoylphenyl)-2-cyclohexyl-2-[(4-fluorophenyl)sulfonylamino]acetamide
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C21H25FN4O3S
  1
1
IC50 = 1290 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0521056
 Compound Info 
(2R)-N-(4-carbamimidoylphenyl)-2-cyclohexyl-2-[[4-(trifluoromethyl)phenyl]sulfonylamino]acetamide
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C22H25F3N4O3S
  1
1
IC50 = 3150 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0384876
 Compound Info 
ethyl 4-[(2R)-3-(3-carbamimidoylphenyl)-2-[[2,4,6-tri(propan-2-yl)phenyl]sulfonylamino]propanoyl]piperazine-1-carboxylate
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C32H47N5O5S
  1
1
IC50 = 6490 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS