| Compound ID |
Compound Name |
Compound Formula |
|
CP0092711
|
4-(2-(4-amino-1,2,5-oxadiazol-3-yl)-6-((R)-2-amino-1-phenylethoxy)-1-ethyl-1H-imidazo[4,5-c]pyridin-4-yl)-2-methylbut-3-yn-2-ol
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C23H25N7O3
|
1
|
| 1 |
IC50 = 40 nM
|
|
|
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CP0122572
|
4-(2-(4-amino-1,2,5-oxadiazol-3-yl)-6-((S)-3-amino-1-phenylpropoxy)-1-ethyl-1H-imidazo[4,5-c]pyridin-4-yl)-2-methylbut-3-yn-2-ol
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|
C24H27N7O3
|
1
|
| 1 |
IC50 = 41 nM
|
|
|
|
CP0135917
|
(S)-1-(6-(furan-3-yl)-5-(3-methyl-1H-pyrazolo[3,4-c]pyridin-5-yl)pyridin-3-yloxy)-3-(1H-indol-3-yl)propan-2-amine
Show/Hide
|
C27H24N6O2
|
1
|
| 1 |
IC50 = 64 nM
|
|
|
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CP0046864
|
4-(2-(4-amino-1,2,5-oxadiazol-3-yl)-6-((R)-2-amino-3-phenylpropoxy)-1-ethyl-1H-imidazo[4,5-c]pyridin-4-yl)-2-methylbut-3-yn-2-ol
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|
C24H27N7O3
|
1
|
| 1 |
IC50 = 80 nM
|
|
|
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CP0041156
|
4-[2-(4-amino-1,2,5-oxadiazol-3-yl)-1-ethyl-7-[(3S)-piperidin-3-ylmethoxy]-1H-imidazo[4,5-c]pyridin-4-yl]-2-methylbut-3-yn-2-ol
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|
C21H27N7O3
|
1
|
| 1 |
IC50 = 138 nM
|
|
|
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CP0214886
|
(S)-1-(6-(furan-3-yl)-5-(3-methyl-1H-pyrazolo[4,3-b]pyrazin-5-yl)pyridin-3-yloxy)-3-(1H-indol-3-yl)propan-2-amine
Show/Hide
|
C26H23N7O2
|
1
|
| 1 |
IC50 = 160 nM
|
|
|
|
CP0037802
|
4-(2-(4-amino-1,2,5-oxadiazol-3-yl)-6-((S)-2-amino-1-phenylethoxy)-1-ethyl-1H-imidazo[4,5-c]pyridin-4-yl)-2-methylbut-3-yn-2-ol
Show/Hide
|
C23H25N7O3
|
1
|
| 1 |
IC50 = 190 nM
|
|
|
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CP0191433
|
(2S)-1-(1H-indol-3-yl)-3-(5-(3-methyl-1H-pyrazolo[4,3-b]pyrazin-5-yl)-6-(2-methylfuran-3-yl)pyridin-3-yloxy)propan-2-amine
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|
C27H25N7O2
|
1
|
| 1 |
IC50 = 210 nM
|
|
|
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CP0265167
|
3-((S)-2-amino-3-(1H-indol-3-yl)propoxy)-5-(3-methyl-1H-indazol-5-yl)-6-(2-methylfuran-3-yl)pyridin-2-amine
Show/Hide
|
C29H28N6O2
|
1
|
| 1 |
IC50 = 220 nM
|
|
|
|
CP0096184
|
(S)-1-(6-(furan-3-yl)-5-(3-methyl-1H-pyrazolo[3,4-b]pyridin-5-yl)pyridin-3-yloxy)-3-(1H-indol-3-yl)propan-2-amine
Show/Hide
|
C27H24N6O2
|
1
|
| 1 |
IC50 = 260 nM
|
|
|
|
CP0166320
|
3-((S)-2-amino-3-phenylpropoxy)-5-(3-methyl-1H-pyrazolo[4,3-b]pyrazin-5-yl)-6-(2-methylfuran-3-yl)pyridin-2-amine
Show/Hide
|
C25H25N7O2
|
1
|
| 1 |
IC50 = 280 nM
|
|
|
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CP0353118
|
(S)-1-(6-(furan-3-yl)-2-methyl-5-(3-methyl-1H-pyrazolo[4,3-b]pyrazin-5-yl)pyridin-3-yloxy)-3-(1H-indol-3-yl)propan-2-amine
Show/Hide
|
C27H25N7O2
|
1
|
| 1 |
IC50 = 280 nM
|
|
|
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CP0203713
|
3-((S)-2-amino-3-(2-chloro-1H-indol-3-yl)propoxy)-5-(3-methyl-1H-pyrazolo[4,3-b]pyrazin-5-yl)-6-(2-methylfuran-3-yl)pyridin-2-amine
Show/Hide
|
C27H25ClN8O2
|
1
|
| 1 |
IC50 = 300 nM
|
|
|
|
CP0046866
|
4-(2-(4-amino-1,2,5-oxadiazol-3-yl)-1-ethyl-6-((methylamino)methyl)-1H-imidazo[4,5-c]pyridin-4-yl)-2-methylbut-3-yn-2-ol
Show/Hide
|
C17H21N7O2
|
1
|
| 1 |
IC50 = 303 nM
|
|
|
|
CP0293987
|
4-(2-(4-amino-1,2,5-oxadiazol-3-yl)-6-((S)-2-amino-3-phenylpropoxy)-1-ethyl-1H-imidazo[4,5-c]pyridin-4-yl)-2-methylbut-3-yn-2-ol
Show/Hide
|
C24H27N7O3
|
1
|
| 1 |
IC50 = 310 nM
|
|
|
|
CP0128025
|
4-(2-(4-amino-1,2,5-oxadiazol-3-yl)-6-((dimethylamino)methyl)-1-ethyl-1H-imidazo[4,5-c]pyridin-4-yl)-2-methylbut-3-yn-2-ol
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|
C18H23N7O2
|
1
|
| 1 |
IC50 = 375 nM
|
|
|
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CP0293986
|
4-(2-(4-amino-1,2,5-oxadiazol-3-yl)-6-((R)-2-aminopropoxy)-1-ethyl-1H-imidazo[4,5-c]pyridin-4-yl)-2-methylbut-3-yn-2-ol
Show/Hide
|
C18H23N7O3
|
1
|
| 1 |
IC50 = 400 nM
|
|
|
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CP0265168
|
3-((S)-2-amino-3-(1H-indol-3-yl)propoxy)-5-(3-methyl-1H-pyrazolo[3,4-b]pyridin-5-yl)-6-(2-methylfuran-3-yl)pyridin-2-amine
Show/Hide
|
C28H27N7O2
|
1
|
| 1 |
IC50 = 470 nM
|
|
|
|
CP0095882
|
(2S)-1-{[6-furan-3-yl-5-(3-methyl-2H-indazol-5-yl)pyridin-3-yl]oxy}-3-(1H-indol-3-yl)propan-2-amine
Show/Hide
|
C28H25N5O2
|
1
|
| 1 |
IC50 = 500 nM
|
|
|
|
CP0043499
|
3-((S)-2-amino-3-(1H-indol-3-yl)propoxy)-5-(3-methyl-1H-pyrazolo[4,3-b]pyrazin-5-yl)-6-(2-methylfuran-3-yl)pyridin-2-amine
Show/Hide
|
C27H26N8O2
|
1
|
| 1 |
IC50 = 560 nM
|
|
|
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CP0151263
|
(S)-1-(6-(furan-3-yl)-5-(3-methyl-1H-pyrazolo[4,3-d]pyrimidin-5-yl)pyridin-3-yloxy)-3-(1H-indol-3-yl)propan-2-amine
Show/Hide
|
C26H23N7O2
|
1
|
| 1 |
IC50 = 670 nM
|
|
|
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CP0225983
|
3-((S)-2-amino-3-(1H-indol-3-yl)propoxy)-5-(3-methyl-1H-pyrazolo[3,4-c]pyridin-5-yl)-6-(2-methylfuran-3-yl)pyridin-2-amine
Show/Hide
|
C28H27N7O2
|
1
|
| 1 |
IC50 = 680 nM
|
|
|
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CP0194822
|
4-(2-(4-amino-1,2,5-oxadiazol-3-yl)-6-(aminomethyl)-1-ethyl-1H-imidazo[4,5-c]pyridin-4-yl)-2-methylbut-3-yn-2-ol
Show/Hide
|
C16H19N7O2
|
1
|
| 1 |
IC50 = 1020 nM
|
|
|
|
CP0019688
|
4-(2-(4-amino-1,2,5-oxadiazol-3-yl)-6-((S)-2-amino-2-phenylethoxy)-1-ethyl-1H-imidazo[4,5-c]pyridin-4-yl)-2-methylbut-3-yn-2-ol
Show/Hide
|
C23H25N7O3
|
1
|
| 1 |
IC50 = 1040 nM
|
|
|
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CP0020881
|
4-(2-(4-amino-1,2,5-oxadiazol-3-yl)-6-((R)-2-amino-2-phenylethoxy)-1-ethyl-1H-imidazo[4,5-c]pyridin-4-yl)-2-methylbut-3-yn-2-ol
Show/Hide
|
C23H25N7O3
|
1
|
| 1 |
IC50 = 1110 nM
|
|
|
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CP0274796
|
4-(2-(4-amino-1,2,5-oxadiazol-3-yl)-6-(2-aminoethoxy)-1-ethyl-1H-imidazo[4,5-c]pyridin-4-yl)-2-methylbut-3-yn-2-ol
Show/Hide
|
C17H21N7O3
|
1
|
| 1 |
IC50 = 1140 nM
|
|
|
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CP0046858
|
4-(2-(4-amino-1,2,5-oxadiazol-3-yl)-6-((S)-2-aminopropoxy)-1-ethyl-1H-imidazo[4,5-c]pyridin-4-yl)-2-methylbut-3-yn-2-ol
Show/Hide
|
C18H23N7O3
|
1
|
| 1 |
IC50 = 1210 nM
|
|
|
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CP0046892
|
4-(2-(4-amino-1,2,5-oxadiazol-3-yl)-6-((R)-3-amino-1-phenylpropoxy)-1-ethyl-1H-imidazo[4,5-c]pyridin-4-yl)-2-methylbut-3-yn-2-ol
Show/Hide
|
C24H27N7O3
|
1
|
| 1 |
IC50 = 1570 nM
|
|
|
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CP0271240
|
4-(2-(4-amino-1,2,5-oxadiazol-3-yl)-1-ethyl-6-(2-(methylamino)ethoxy)-1H-imidazo[4,5-c]pyridin-4-yl)-2-methylbut-3-yn-2-ol
Show/Hide
|
C18H23N7O3
|
1
|
| 1 |
IC50 = 2600 nM
|
|
|
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CP0021627
|
4-(2-(4-amino-1,2,5-oxadiazol-3-yl)-1-ethyl-6-(pyrrolidin-1-ylmethyl)-1H-imidazo[4,5-c]pyridin-4-yl)-2-methylbut-3-yn-2-ol
Show/Hide
|
C20H25N7O2
|
1
|
| 1 |
IC50 = 2700 nM
|
|
|
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CP0151265
|
(S)-1-(6-(furan-3-yl)-5-(3-methyl-1H-pyrazolo[4,3-b]pyridin-5-yl)pyridin-3-yloxy)-3-(1H-indol-3-yl)propan-2-amine
Show/Hide
|
C27H24N6O2
|
1
|
| 1 |
IC50 = 3860 nM
|
|
|
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CP0244689
|
4-(2-(4-amino-1,2,5-oxadiazol-3-yl)-6-(2-aminoethyl)-1-ethyl-1H-imidazo[4,5-c]pyridin-4-yl)-2-methylbut-3-yn-2-ol
Show/Hide
|
C17H21N7O2
|
1
|
| 1 |
IC50 = 4000 nM
|
|
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CP0203712
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(S)-3-(2-amino-3-phenylpropoxy)-N-ethyl-6-(furan-3-yl)-5-(3-methyl-1H-pyrazolo[4,3-b]pyrazin-5-yl)pyridin-2-amine
Show/Hide
|
C26H27N7O2
|
1
|
| 1 |
IC50 > 10000 nM
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|
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CP0225984
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(S)-3-(2-amino-3-(1H-indol-3-yl)propoxy)-6-(furan-3-yl)-5-(3-methyl-1H-pyrazolo[4,3-b]pyrazin-5-yl)picolinonitrile
Show/Hide
|
C27H22N8O2
|
1
|
| 1 |
IC50 > 10000 nM
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|
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CP0274799
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4-(2-(4-amino-1,2,5-oxadiazol-3-yl)-6-(3-aminopropyl)-1-ethyl-1H-imidazo[4,5-c]pyridin-4-yl)-2-methylbut-3-yn-2-ol
Show/Hide
|
C18H23N7O2
|
1
|
| 1 |
IC50 = 13200 nM
|
|
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CP0128460
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3-((2S)-2-amino-3-(2-amino-5-(3-methyl-1H-pyrazolo[4,3-b]pyrazin-5-yl)-6-(2-methylfuran-3-yl)pyridin-3-yloxy)propyl)-1H-indole-2-carboxamide
Show/Hide
|
C28H27N9O3
|
1
|
| 1 |
IC50 > 30000 nM
|
|
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CP0203714
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3-((2S)-2-amino-3-(2-amino-5-(3-methyl-1H-pyrazolo[4,3-b]pyrazin-5-yl)-6-(2-methylfuran-3-yl)pyridin-3-yloxy)propyl)-1H-indole-2-carbonitrile
Show/Hide
|
C28H25N9O2
|
1
|
| 1 |
IC50 > 30000 nM
|
|
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CP0040407
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4-(2-(4-amino-1,2,5-oxadiazol-3-yl)-6-(3-aminopropoxy)-1-ethyl-1H-imidazo[4,5-c]pyridin-4-yl)-2-methylbut-3-yn-2-ol
Show/Hide
|
C18H23N7O3
|
1
|
| 1 |
IC50 = 30000 nM
|
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CP0271239
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4-(2-(4-amino-1,2,5-oxadiazol-3-yl)-6-(4-aminobutoxy)-1-ethyl-1H-imidazo[4,5-c]pyridin-4-yl)-2-methylbut-3-yn-2-ol
Show/Hide
|
C19H25N7O3
|
1
|
| 1 |
IC50 = 30000 nM
|
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