Brief Information of the Cell Line and Protein
Cell Line ID: CL000207 , MIA PaCa-2
 Cell Line Info 
Synonyms
MIA-PaCa-2
MIA-PACA-2
MIA-Pa-Ca-2
MIA Paca2
MIA PaCa2
MiaPaCa-2
MIAPACA-2
MiaPaca.2
MiaPaCa2
Miapaca2
MIAPaCa2
MIAPACA2
Mia PACA 2
MIAPaCa-2
PaCa2
MiaPaCa
Category Cancer cell line
Organism
Homo sapiens (Human)
Cellosaurus ID
CVCL_0428
Protein ID: PT00922 , Epidermal growth factor receptor
 Protein Info 
Gene Name EGFR
Organism Homo sapiens, Human
Protein Classification Kinase
Uniprot ID P00533
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000207
 Cell Line Info 
 Protein ID: PT00922
 Protein Info 
 
Compound ID Compound Name Compound Formula
CP0137470
 Compound Info 
3-{2-[(2-methoxyphenyl)methyl]-1H-1,3-benzodiazol-6-yl}-1-{4-[4-(3-methoxypropyl)piperazin-1-yl]cyclohexyl}-1H-pyrazolo[3,4-d]pyrimidin-4-amine
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C34H43N9O2
  1
1
EC50 = 85 nM
 Bioactivity Info 
   TI
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CP0198587
 Compound Info 
1-{4-[4-(cyclopropylmethyl)piperazin-1-yl]cyclohexyl}-3-{2-[(2-methoxyphenyl)methyl]-1H-1,3-benzodiazol-6-yl}-1H-pyrazolo[3,4-d]pyrimidin-4-amine
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C34H41N9O
  1
1
EC50 = 91 nM
 Bioactivity Info 
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CP0198677
 Compound Info 
3-{2-[(2-methoxyphenyl)methyl]-1H-1,3-benzodiazol-6-yl}-1-[4-(piperazin-1-yl)cyclohexyl]-1H-pyrazolo[3,4-d]pyrimidin-4-amine
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C30H35N9O
  1
1
EC50 = 335 nM
 Bioactivity Info 
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CP0352335
 Compound Info 
ethyl 4-[4-(4-amino-3-{2-[(2-methoxyphenyl)methyl]-1H-1,3-benzodiazol-6-yl}-1H-pyrazolo[3,4-d]pyrimidin-1-yl)cyclohexyl]piperazine-1-carboxylate
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C33H39N9O3
  1
1
EC50 = 520 nM
 Bioactivity Info 
   TI
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CP0269331
 Compound Info 
1-{4-[4-(4-amino-3-{2-[(2-methoxyphenyl)methyl]-1H-1,3-benzodiazol-6-yl}-1H-pyrazolo[3,4-d]pyrimidin-1-yl)cyclohexyl]piperazin-1-yl}ethan-1-one
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C32H37N9O2
  1
1
EC50 = 742 nM
 Bioactivity Info 
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CP0245059
 Compound Info 
4-[4-(4-amino-3-{2-[(2-methoxyphenyl)methyl]-1H-1,3-benzodiazol-6-yl}-1H-pyrazolo[3,4-d]pyrimidin-1-yl)cyclohexyl]-N,N-dimethylpiperazine-1-carboxamide
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C33H40N10O2
  1
1
EC50 = 808 nM
 Bioactivity Info 
   TI
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