Brief Information of the Cell Line and Protein
Cell Line ID: CL000194 , RBL-1
 Cell Line Info 
Synonyms
RBL 1
RBL-I
RBL
Rat Basophilic Leukemia-1
Category Cancer cell line
Organism
Rattus norvegicus (Rat)
Cellosaurus ID
CVCL_0496
Protein ID: PT06573 , Tryptophan 5-hydroxylase 1
 Protein Info 
Gene Name TPH1
Organism Rattus norvegicus, Rat
Protein Classification Enzyme
Uniprot ID P09810
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000194
 Cell Line Info 
 Protein ID: PT06573
 Protein Info 
 
Compound ID Compound Name Compound Formula
CP0344579
 Compound Info 
(2S)-2-amino-3-(4-(2-amino-6-(2,2,2-trifluoro-1-(2-(furan-2-yl)phenyl)ethoxy)pyrimidin-4-yl)phenyl)propanoic acid
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C25H21F3N4O4
  1
1
EC50 = 48 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0302983
 Compound Info 
(S)-2-Amino-3-(4-{2-amino-6-[2,2,2-trifluoro-1-(3'-methylbiphenyl-2-yl)-ethoxy]-pyrimidin-4-yl}-phenyl)propionic acid
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C28H25F3N4O3
  1
1
EC50 = 56 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0264690
 Compound Info 
(2S)-2-amino-3-(4-(2-amino-6-(2,2,2-trifluoro-1-(3-(furan-2-yl)thiophen-2-yl)ethoxy)pyrimidin-4-yl) phenyl)propanoic acid
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C23H19F3N4O4S
  1
1
EC50 = 63 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0191325
 Compound Info 
(S) -2-amino-3-[4-(2-amino-6-[2,2,2-trifluoro-1-(2-(3-trifluoromethyl-pyrazol-1-yl-phenyl)-ethoxy]-pyrimidin-4-yl]-phenyl-propionic acid
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C25H20F6N6O3
  1
1
EC50 = 70 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0307813
 Compound Info 
(2S)-2-amino-3-(4-(2-amino-6-(2,2,2-trifluoro-1-(naphthalen-2-yl)ethoxy)pyrimidin-4-yl)phenyl)propanoic acid
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C25H21F3N4O3
  1
1
EC50 = 510 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0214308
 Compound Info 
(S)-2-amino-3-(4-(2-amino-6-((R)-1-(naphthalen-2-yl)ethylamino)pyrimidin-4-yl)phenyl)propanoic acid
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C25H25N5O2
  1
1
EC50 = 1700 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0341405
 Compound Info 
(S)-2-amino-3-(4-(2-amino-6-((R)-1-(naphthalen-2-yl)ethoxy)pyrimidin-4-yl)phenyl)propanoic acid
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C25H24N4O3
  1
1
EC50 = 11000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS