Brief Information of the Cell Line and Protein
Cell Line ID: CL000194 , RBL-1
Synonyms
RBL 1
RBL-I
RBL
Rat Basophilic Leukemia-1
Category Cancer cell line
Organism
Rattus norvegicus (Rat)
Cellosaurus ID
CVCL_0496
Protein ID: PT02772 , C5a anaphylatoxin chemotactic receptor 1
Gene Name C5AR1
Organism Homo sapiens, Human
Protein Classification Membrane receptor
Uniprot ID P21730
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000194  Protein ID: PT02772
 
Compound ID Compound Name Compound Formula
CP0464587
Ac-Phe-[Orn-Pro-cha-Trp-Orn]
   Show/Hide
C46H63N9O7
 1
1
IC50 = 18 nM
   TI
   LI
   LO
   TS
CP0522895
Ac-Phe-[Orn-Pro-cha-Trp-Nva]
   Show/Hide
C46H62N8O7
 1
1
IC50 = 18 nM
   TI
   LI
   LO
   TS
CP0376163
Ac-Ala-[Orn-Pro-cha-Trp-Eag]
   Show/Hide
C45H57N9O7
 1
1
IC50 = 19 nM
   TI
   LI
   LO
   TS
CP0542896
Ac-Phe-[Orn-Pro-cha-Trp-Thi]
   Show/Hide
C48H60N8O7S
 1
1
IC50 = 22 nM
   TI
   LI
   LO
   TS
CP0456452
Ac-Phe-[Orn-Pro-cha-Trp-Nle]
   Show/Hide
C47H64N8O7
 1
1
IC50 = 25 nM
   TI
   LI
   LO
   TS
CP0541724
Ac-Phe-[Orn-Ala-cha-Trp-Arg]
   Show/Hide
C45H63N11O7
 1
1
IC50 = 25 nM
   TI
   LI
   LO
   TS
CP0456455
Ac-Phe-[Orn-Pro-cha-Trp-Phe]
   Show/Hide
C50H62N8O7
 1
1
IC50 = 26 nM
   TI
   LI
   LO
   TS
CP0485629
Ac-Phe-Orn-Pro-hle-Bta-Phe-NH2
   Show/Hide
C48H62N8O7S
 1
1
IC50 = 27 nM
   TI
   LI
   LO
   TS
CP0045051
(S)-N-((3R,6S,9S,15S,20aS)-6-((1H-indol-3-yl)methyl)-3-(cyclohexylmethyl)-9-(3-guanidinopropyl)-1,4,7,10,16-pentaoxoicosahydropyrrolo[1,2-a][1,4,7,10,13]pentaazacyclooctadecin-15-yl)-2-acetamido-3-phenylpropanamide
   Show/Hide
C47H65N11O7
 1
1
IC50 = 29 nM
   TI
   LI
   LO
   TS
CP0541687
Ac-Phe-Orn-Pro-cha-Trp-Phe-NH2
   Show/Hide
C50H65N9O7
 1
1
IC50 = 31 nM
   TI
   LI
   LO
   TS
CP0554714
Ac-Phe-[Orn-Pro-cha-Trp-Chg]
   Show/Hide
C49H66N8O7
 1
1
IC50 = 38 nM
   TI
   LI
   LO
   TS
CP0668763
Hoo-Phe-Orn-Pro-hle-Pff-Phe-NH2
   Show/Hide
C49H63FN10O9
 1
1
IC50 = 39 nM
   TI
   LI
   LO
   TS
CP0485628
Ac-Phe-[Orn-Pro-cha-Trp-Cha]
   Show/Hide
C50H68N8O7
 1
1
IC50 = 45 nM
   TI
   LI
   LO
   TS
CP0502428
Ac-Phe-[Orn-Pro-cha-Trp-Ile]
   Show/Hide
C47H64N8O7
 1
1
IC50 = 50 nM
   TI
   LI
   LO
   TS
CP0554713
Ac-Phe-[Orn-Pro-cha-Trp-1Ni]
   Show/Hide
C54H64N8O7
 1
1
IC50 = 51 nM
   TI
   LI
   LO
   TS
CP0408313
Ac-Phe-[Orn-Pro-cha-Trp-Leu]
   Show/Hide
C47H64N8O7
 1
1
IC50 = 54 nM
   TI
   LI
   LO
   TS
CP0408312
Ac-Phe-[Orn-Pro-cha-Trp-Hle]
   Show/Hide
C48H66N8O7
 1
1
IC50 = 57 nM
   TI
   LI
   LO
   TS
CP0523764
Ac-Phe-Orn-Pro-hle-Mcf-Phe-NH2
   Show/Hide
C46H61ClN8O7
 1
1
IC50 = 60 nM
   TI
   LI
   LO
   TS
CP0503047
Ac-Phe-Orn-Pro-hle-Trp-Phe-NH2
   Show/Hide
C48H63N9O7
 1
1
IC50 = 63 nM
   TI
   LI
   LO
   TS
CP0391028
Ac-Phe-Orn-Pro-hle-Pff-Phe-NH2
   Show/Hide
C46H61FN8O7
 1
1
IC50 = 71 nM
   TI
   LI
   LO
   TS
CP0502522
Ac-Phe-[Orn-Pro-cha-Trp-2Ni]
   Show/Hide
C54H64N8O7
 1
1
IC50 = 76 nM
   TI
   LI
   LO
   TS
CP0453071
Ac-Phe-[Orn-Pro-cha-Trp-nle]
   Show/Hide
C47H64N8O7
 1
1
IC50 = 107 nM
   TI
   LI
   LO
   TS
CP0541693
Ac-Phe-Orn-Pro-hle-Dcf-Phe-NH2
   Show/Hide
C46H60Cl2N8O7
 1
1
IC50 = 116 nM
   TI
   LI
   LO
   TS
CP0541699
Ac-Phe-[Orn-Pro-cha-Trp-Hch]
   Show/Hide
C51H70N8O7
 1
1
IC50 = 146 nM
   TI
   LI
   LO
   TS
CP0441805
Ac-Phe-Orn-Pro-cha-Trp-Arg-NH2
   Show/Hide
C47H68N12O7
 1
1
IC50 = 190 nM
   TI
   LI
   LO
   TS
CP0485626
Ac-Phe-[Orn-Pro-cha-Trp-Ocg]
   Show/Hide
C51H72N8O7
 1
1
IC50 = 300 nM
   TI
   LI
   LO
   TS
CP0456454
Ac-Phe-[Orn-Pro-cha-Trp-Har]
   Show/Hide
C48H67N11O7
 1
1
IC50 = 360 nM
   TI
   LI
   LO
   TS
CP0512059
Ac-Phe-Orn-Pro-cha-Trp-Nle-NH2
   Show/Hide
C47H67N9O7
 1
1
IC50 = 463 nM
   TI
   LI
   LO
   TS
CP0453069
Ac-Phe-[Orn-Pro-cha-Trp-Cit]
   Show/Hide
C47H64N10O8
 1
1
IC50 = 490 nM
   TI
   LI
   LO
   TS
CP0499592
Ac-Phe-Orn-Pro-cha-Trp-Arg-OH
   Show/Hide
C47H67N11O8
 1
1
IC50 = 535 nM
   TI
   LI
   LO
   TS
CP0554712
Ac-Phe-[Orn-Pro-cha-Trp-Arg(NO2)]
   Show/Hide
C47H64N12O9
 1
1
IC50 = 570 nM
   TI
   LI
   LO
   TS
CP0499590
Ac-Phe-[Orn-Pro-cha-Trp-Ala]
   Show/Hide
C44H58N8O7
 1
1
IC50 = 6900 nM
   TI
   LI
   LO
   TS
CP0499591
Ac-Phe-[Orn-Pro-cha-Trp-Lys]
   Show/Hide
C47H65N9O7
 1
1
IC50 = 8700 nM
   TI
   LI
   LO
   TS
CP0554711
Ac-Ala-[Orn-Pro-cha-Trp-Arg]
   Show/Hide
C41H61N11O7
 1
1
IC50 = 23000 nM
   TI
   LI
   LO
   TS
CP0554710
Ac-Phe-[Orn-Pro-ala-Trp-Arg]
   Show/Hide
C41H55N11O7
 1
1
IC50 = 55000 nM
   TI
   LI
   LO
   TS
CP0441782
Ac-Phe-[Orn-Pro-cha-Ala-Arg]
   Show/Hide
C39H60N10O7
 1
1
IC50 = 100000 nM
   TI
   LI
   LO
   TS