Brief Information of the Cell Line and Protein
Cell Line ID: CL000194 , RBL-1
Synonyms
RBL 1
RBL-I
RBL
Rat Basophilic Leukemia-1
Category Cancer cell line
Organism
Rattus norvegicus (Rat)
Cellosaurus ID
CVCL_0496
Protein ID: PT00961 , Fatty-acid amide hydrolase 1
Gene Name FAAH
Organism Rattus norvegicus, Rat
Protein Classification Enzyme
Uniprot ID P97612
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000194  Protein ID: PT00961
 
Compound ID Compound Name Compound Formula
CP0219188
(S)-3-(1-(4-(benzo[b]thiophen-2-yl)pyrimidin-2-yl)piperidin-3-yl)-1-ethyl-1H-imidazo[4,5-b]pyridin-2(3H)-one
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C25H24N6OS
 1
1
EC50 = 80 nM
   TI
   LI
   LO
   TS
CP0142669
(S)-3-(1-(4-(5-chlorothiophen-2-yl)pyrimidin-2-yl)piperidin-3-yl)-1-(2,2,2-trifluoroethyl)-1H-imidazo[4,5-b]pyridin-2(3H)-one
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C21H18ClF3N6OS
 1
1
EC50 = 100 nM
   TI
   LI
   LO
   TS
CP0219116
(S)-3-(1-(2-amino-6-(4-fluorophenyl)pyrimidin-4-yl)piperidin-3-yl)-1-ethyl-1H-imidazo[4,5-b]pyridin-2(3H)-one
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C23H24FN7O
 1
1
EC50 = 100 nM
   TI
   LI
   LO
   TS
CP0219186
(S)-3-(1-(4-(5-chlorothiophen-2-yl)pyrimidin-2-yl)piperidin-3-yl)-1-ethyl-1H-imidazo[4,5-b]pyridin-2(3H)-one
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C21H21ClN6OS
 1
1
EC50 = 280 nM
   TI
   LI
   LO
   TS
CP0271866
(S)-1-ethyl-3-(1-(4-(thiophen-2-yl)pyrimidin-2-yl)piperidin-3-yl)-1H-imidazo[4,5-b]pyridin-2(3H)-one
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C21H22N6OS
 1
1
EC50 = 1800 nM
   TI
   LI
   LO
   TS