Brief Information of the Cell Line and Protein
Cell Line ID: CL000186 , RPMI-8226
 Cell Line Info 
Synonyms
RPMI 8226
RPMI.8226
RPMI8226
RPMI no. 8226
RPMI no 8226
RPMI #8226
8226
RPMI 8226/S
RPMI-8226S
RPMI8226/S
8226/S
Roswell Park Memorial Institute 8226
GM02132
GM2132
GM 2132
GM02132C
Simpson
Category Cancer cell line
Organism
Homo sapiens (Human)
Cellosaurus ID
CVCL_0014
Protein ID: PT03496 , Proteasome subunit beta type-10
 Protein Info 
Gene Name PSMB10
Organism Homo sapiens, Human
Protein Classification Enzyme
Uniprot ID P40306
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000186
 Cell Line Info 
 Protein ID: PT03496
 Protein Info 
 
Compound ID Compound Name Compound Formula
CP0476403
 Compound Info 
(2S)-N-[(2S)-1-[[(E,2S)-1-[4-(aminomethyl)phenyl]-4-methylsulfonylbut-3-en-2-yl]amino]-4-methyl-1-oxopentan-2-yl]-2-[[(2S)-2-[(2-azidoacetyl)amino]-3-phenylpropanoyl]amino]-4-methylpentanamide
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C35H50N8O6S
  1
1
IC50 = 22 nM
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CP0553755
 Compound Info 
N-[(2S)-1-[[(2S)-1-[[(E,2S)-1-[4-(aminomethyl)phenyl]-4-methylsulfonylbut-3-en-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]-6-phenylpyridine-3-carboxamide
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C36H47N5O5S
  1
1
IC50 = 23 nM
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CP0536885
 Compound Info 
(2S)-2-[[(2S)-3-[4-(aminomethyl)phenyl]-2-[[(2S)-2-azido-3-phenylpropanoyl]amino]propanoyl]amino]-N-[(2S)-4-cyclohexyl-1-[(2R)-2-methyloxiran-2-yl]-1-oxobutan-2-yl]-3-methylbutanamide
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C37H51N7O5
  1
1
IC50 = 39 nM
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CP0476387
 Compound Info 
N-[(2S)-1-[[(2S)-1-[[(E,2S)-1-[4-(aminomethyl)phenyl]-4-methylsulfonylbut-3-en-2-yl]amino]-3-(4-cyclohexylcyclohexyl)-1-oxopropan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]-2-methyl-1,3-thiazole-5-carboxamide
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C38H57N5O5S2
  1
1
IC50 = 45 nM
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CP0446741
 Compound Info 
(2S)-N-[(2S)-1-[[(E,2S)-1-[4-(aminomethyl)phenyl]-4-methylsulfonylbut-3-en-2-yl]amino]-4-methyl-1-oxopentan-2-yl]-4-methyl-2-[(2-morpholin-4-ylacetyl)amino]pentanamide
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C30H49N5O6S
  1
1
IC50 = 47 nM
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CP0508331
 Compound Info 
(2S)-N-[(E,2S)-1-[4-(aminomethyl)phenyl]-4-methylsulfonylbut-3-en-2-yl]-2-[[(2S)-2-[[(2S)-2-azido-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]-4-fluoro-4-methylpentanamide
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C33H46FN7O5S
  1
1
IC50 = 47 nM
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CP0535352
 Compound Info 
N-[(1S)-2-[[(2S)-1-[[(E,2S)-1-[4-(aminomethyl)phenyl]-4-methylsulfonylbut-3-en-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-1-cyclohexyl-2-oxoethyl]-2-methyl-1,3-thiazole-5-carboxamide
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C31H45N5O5S2
  1
1
IC50 = 61 nM
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CP0476389
 Compound Info 
(2S)-2-[[(2S)-3-[4-(aminomethyl)phenyl]-2-[[(2S)-2-azido-3-phenylpropanoyl]amino]propanoyl]amino]-3-methyl-N-[(2S)-3-(4-methylcyclohexyl)-1-[(2R)-2-methyloxiran-2-yl]-1-oxopropan-2-yl]butanamide
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C37H51N7O5
  1
1
IC50 = 97 nM
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CP0446746
 Compound Info 
N-[(2S)-1-[[(2S)-1-[[(E,2S)-1-[4-(aminomethyl)phenyl]-4-methylsulfonylbut-3-en-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]benzamide
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C31H44N4O5S
  1
1
IC50 = 106 nM
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CP0455536
 Compound Info 
(2S)-N-[(2S)-1-[[(E,2S)-1-[4-(aminomethyl)phenyl]-4-methylsulfonylbut-3-en-2-yl]amino]-4,4,4-trifluoro-1-oxobutan-2-yl]-2-[[(2S)-2-azido-3-phenylpropanoyl]amino]-4-methylpentanamide
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C31H40F3N7O5S
  1
1
IC50 = 130 nM
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CP0563686
 Compound Info 
N-[(2S)-1-[[(2S)-3-(1,2,3,4,4a,5,6,7,8,8a-decahydronaphthalen-2-yl)-1-[[(E,2S)-1-[4-(aminomethyl)phenyl]-4-methylsulfonylbut-3-en-2-yl]amino]-1-oxopropan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]-2-methyl-1,3-thiazole-5-carboxamide
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C36H53N5O5S2
  1
1
IC50 = 170 nM
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CP0476383
 Compound Info 
N-[(2S)-1-[[(2S)-3-(1,2,3,4,4a,5,6,7,8,8a-decahydronaphthalen-1-yl)-1-[[(E,2S)-1-[4-(aminomethyl)phenyl]-4-methylsulfonylbut-3-en-2-yl]amino]-1-oxopropan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]-2-methyl-1,3-thiazole-5-carboxamide
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C36H53N5O5S2
  1
1
IC50 = 175 nM
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CP0446747
 Compound Info 
(2S)-N-[(2S)-1-[[(E,2S)-1-[4-(aminomethyl)phenyl]-4-methylsulfonylbut-3-en-2-yl]amino]-3-methoxy-1-oxopropan-2-yl]-2-[[(2S)-2-azido-3-phenylpropanoyl]amino]-4-methylpentanamide
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C31H43N7O6S
  1
1
IC50 = 200 nM
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CP0536884
 Compound Info 
N-[(2S)-1-[[(2S)-1-[[(E,2S)-1-[4-(aminomethyl)phenyl]-4-methylsulfonylbut-3-en-2-yl]amino]-3-(4-methylcyclohexyl)-1-oxopropan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]-2-methyl-1,3-thiazole-5-carboxamide
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C33H49N5O5S2
  1
1
IC50 = 200 nM
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CP0431914
 Compound Info 
N-[(2S)-1-[[(2S)-1-[[(E,2S)-1-[4-(aminomethyl)phenyl]-4-methylsulfonylbut-3-en-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-4-cyclohexyl-1-oxobutan-2-yl]-2-methyl-1,3-thiazole-5-carboxamide
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C33H49N5O5S2
  1
1
IC50 = 204 nM
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CP0476386
 Compound Info 
(2S)-N-[(2S)-3-(1,2,3,4,4a,5,6,7,8,8a-decahydronaphthalen-2-yl)-1-[(2R)-2-methyloxiran-2-yl]-1-oxopropan-2-yl]-2-[[(2S)-3-[4-(aminomethyl)phenyl]-2-[[(2S)-2-azido-3-phenylpropanoyl]amino]propanoyl]amino]-3-methylbutanamide
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C40H55N7O5
  1
1
IC50 = 230 nM
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CP0476381
 Compound Info 
N-[(2S)-1-[[(2S)-1-[[(E,2S)-1-[4-(aminomethyl)phenyl]-4-methylsulfonylbut-3-en-2-yl]amino]-3-cyclohexyl-1-oxopropan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]-2-methyl-1,3-thiazole-5-carboxamide
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C32H47N5O5S2
  1
1
IC50 = 260 nM
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CP0476382
 Compound Info 
N-[(2S)-1-[[(2S)-1-[[(E,2S)-1-[4-(aminomethyl)phenyl]-4-methylsulfonylbut-3-en-2-yl]amino]-4-cyclohexyl-1-oxobutan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]-2-methyl-1,3-thiazole-5-carboxamide
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C33H49N5O5S2
  1
1
IC50 = 280 nM
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CP0427708
 Compound Info 
(2S)-N-[(2S)-1-[[(E,2S)-1-[4-(aminomethyl)phenyl]-4-methylsulfonylbut-3-en-2-yl]amino]-1-oxopropan-2-yl]-2-[[(2S)-2-azido-3-phenylpropanoyl]amino]-4-methylpentanamide
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C30H41N7O5S
  1
1
IC50 = 325 nM
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CP0535350
 Compound Info 
N-[(2S)-1-[[(2S)-1-[[(E,2S)-1-[4-(aminomethyl)phenyl]-4-methylsulfonylbut-3-en-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-3-(4-methylcyclohexyl)-1-oxopropan-2-yl]-2-methyl-1,3-thiazole-5-carboxamide
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C33H49N5O5S2
  1
1
IC50 = 325 nM
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CP0446750
 Compound Info 
(2S)-N-[(2S,3R)-1-[[(E,2S)-1-[4-(aminomethyl)phenyl]-4-methylsulfonylbut-3-en-2-yl]amino]-3-hydroxy-1-oxobutan-2-yl]-2-[[(2S)-2-azido-3-phenylpropanoyl]amino]-4-methylpentanamide
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C31H43N7O6S
  1
1
IC50 = 330 nM
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CP0446745
 Compound Info 
(2S)-N-[(2S)-3-(1,2,3,4,4a,5,6,7,8,8a-decahydronaphthalen-1-yl)-1-[(2R)-2-methyloxiran-2-yl]-1-oxopropan-2-yl]-2-[[(2S)-3-[4-(aminomethyl)phenyl]-2-[[(2S)-2-azido-3-phenylpropanoyl]amino]propanoyl]amino]-3-methylbutanamide
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C40H55N7O5
  1
1
IC50 = 350 nM
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CP0455541
 Compound Info 
N-[(2S)-1-[[(2S)-1-[[(E,2S)-1-[4-(aminomethyl)phenyl]-4-methylsulfonylbut-3-en-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]-2,5-dichlorobenzamide
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C31H42Cl2N4O5S
  1
1
IC50 = 350 nM
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CP0446744
 Compound Info 
N-[(2S)-1-[[(2S)-1-[[(E,2S)-1-[4-(aminomethyl)phenyl]-4-methylsulfonylbut-3-en-2-yl]amino]-3-(4-methoxycyclohexyl)-1-oxopropan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]-2-methyl-1,3-thiazole-5-carboxamide
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C33H49N5O6S2
  1
1
IC50 = 360 nM
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CP0476384
 Compound Info 
N-[(2S)-1-[[(2S)-1-[[(E,2S)-1-[4-(aminomethyl)phenyl]-4-methylsulfonylbut-3-en-2-yl]amino]-3-cyclohexyl-1-oxopropan-2-yl]amino]-3-cyclohexyl-1-oxopropan-2-yl]-2-methyl-1,3-thiazole-5-carboxamide
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C35H51N5O5S2
  1
1
IC50 = 420 nM
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CP0432043
 Compound Info 
(2S)-N-[(2S)-1-[[(E,2S)-1-[4-(aminomethyl)phenyl]-4-methylsulfonylbut-3-en-2-yl]amino]-3-hydroxy-1-oxopropan-2-yl]-2-[[(2S)-2-azido-3-phenylpropanoyl]amino]-4-methylpentanamide
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C30H41N7O6S
  1
1
IC50 = 525 nM
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CP0423650
 Compound Info 
N-[(2S)-1-[[(2S)-1-[[(E,2S)-1-[4-(aminomethyl)phenyl]-4-methylsulfonylbut-3-en-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-3-cyclohexyl-1-oxopropan-2-yl]-2-methyl-1,3-thiazole-5-carboxamide
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C32H47N5O5S2
  1
1
IC50 = 540 nM
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CP0062987
 Compound Info 
(2S)-3-(4-methoxyphenyl)-N-[(2S)-1-[(2R)-2-methyloxiran-2-yl]-1-oxo-3-phenylpropan-2-yl]-2-[[(2S)-2-[(2-morpholin-4-ylacetyl)amino]propanoyl]amino]propanamide
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C31H40N4O7
  1
1
IC50 = 590 nM
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CP0446742
 Compound Info 
N-[(2S)-1-[[(2S)-1-[[(E,2S)-1-[4-(aminomethyl)phenyl]-4-methylsulfonylbut-3-en-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]-2-methyl-1,3-thiazole-5-carboxamide
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C29H43N5O5S2
  1
1
IC50 = 700 nM
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CP0431919
 Compound Info 
(2S)-2-[[(2S)-3-[4-(aminomethyl)phenyl]-2-[[(2S)-2-azido-3-phenylpropanoyl]amino]propanoyl]amino]-N-[(2S)-3-(4-methoxycyclohexyl)-1-[(2R)-2-methyloxiran-2-yl]-1-oxopropan-2-yl]-3-methylbutanamide
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C37H51N7O6
  1
1
IC50 = 850 nM
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CP0885679
 Compound Info 
(S)-N-((S)-3-cyclohexyl-1-((R)-2-methyloxiran-2-yl)-1-oxopropan-2-yl)-3-(4-methoxyphenyl)-2-((S)-2-(2-morpholinoacetamido)propanamido)propanamide
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C31H46N4O7
  1
1
IC50 = 900 nM
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CP0431920
 Compound Info 
(2S)-2-[[(2S)-3-[4-(aminomethyl)phenyl]-2-[[(2S)-2-azido-3-phenylpropanoyl]amino]propanoyl]amino]-N-[(2S)-3-(2-bicyclo[2.2.1]heptanyl)-1-[(2R)-2-methyloxiran-2-yl]-1-oxopropan-2-yl]-3-methylbutanamide
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C37H49N7O5
  1
1
IC50 = 1150 nM
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CP0446743
 Compound Info 
N-[(2S)-1-[[(2S)-1-[[(E,2S)-1-[4-(aminomethyl)phenyl]-4-methylsulfonylbut-3-en-2-yl]amino]-1-oxopropan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]pyrazine-2-carboxamide
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C26H36N6O5S
  1
1
IC50 = 1350 nM
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CP0572669
 Compound Info 
(2S)-2-[[(2S)-3-[4-(aminomethyl)phenyl]-2-[[(2S)-2-azido-3-phenylpropanoyl]amino]propanoyl]amino]-N-[(2S)-3-(4-cyclohexylcyclohexyl)-1-[(2R)-2-methyloxiran-2-yl]-1-oxopropan-2-yl]-3-methylbutanamide
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C42H59N7O5
  1
1
IC50 = 2300 nM
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CP0455537
 Compound Info 
N-[(2S)-3-(1,2,3,4,4a,5,6,7,8,8a-decahydronaphthalen-2-yl)-1-[[(2S)-1-[[(E,2S)-1-[4-(aminomethyl)phenyl]-4-methylsulfonylbut-3-en-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-1-oxopropan-2-yl]-2-methyl-1,3-thiazole-5-carboxamide
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C36H53N5O5S2
  1
1
IC50 = 4100 nM
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CP0455540
 Compound Info 
(2S)-2-[[(2S)-3-[4-(aminomethyl)phenyl]-2-[[(2S)-2-azido-3-phenylpropanoyl]amino]propanoyl]amino]-N-[(1S)-1-cyclohexyl-2-[(2R)-2-methyloxiran-2-yl]-2-oxoethyl]-3-methylbutanamide
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C35H47N7O5
  1
1
IC50 = 4250 nM
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CP0438681
 Compound Info 
(2S)-N-[2-[[(E,2S)-1-[4-(aminomethyl)phenyl]-4-methylsulfonylbut-3-en-2-yl]amino]-2-oxoethyl]-2-[[(2S)-2-azido-3-phenylpropanoyl]amino]-4-methylpentanamide
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C29H39N7O5S
  1
1
IC50 = 5900 nM
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CP0438680
 Compound Info 
N-[(2S)-1-[[(2S)-1-[[(E,2S)-1-[4-(aminomethyl)phenyl]-4-methylsulfonylbut-3-en-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]pyrazine-2-carboxamide
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C29H42N6O5S
  1
1
IC50 = 6500 nM
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CP0386861
 Compound Info 
(2S)-N-[(2S)-3-cyclohexyl-1-[(2R)-2-methyloxiran-2-yl]-1-oxopropan-2-yl]-3-(4-methoxyphenyl)-2-[[(2R)-2-[(2-morpholin-4-ylacetyl)amino]propanoyl]amino]propanamide
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C31H46N4O7
  1
1
IC50 > 10000 nM
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CP0864816
 Compound Info 
(S)-N-((S)-3-cyclohexyl-1-((R)-2-methyloxiran-2-yl)-1-oxopropan-2-yl)-3-(1H-indol-3-yl)-2-((R)-2-(2-morpholinoacetamido)propanamido)propanamide
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C32H45N5O6
  1
1
IC50 > 10000 nM
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CP0423623
 Compound Info 
(2S)-N-[(2S)-3-(1,2,3,4,4a,5,6,7,8,8a-decahydronaphthalen-1-yl)-1-[(2R)-2-methyloxiran-2-yl]-1-oxopropan-2-yl]-3-(4-methoxyphenyl)-2-[[(2S)-2-[(2-morpholin-4-ylacetyl)amino]propanoyl]amino]propanamide
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C35H52N4O7
  1
1
IC50 > 10000 nM
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CP0431915
 Compound Info 
(2S)-N-[(2S)-3-(4-methoxycyclohexyl)-1-[(2R)-2-methyloxiran-2-yl]-1-oxopropan-2-yl]-3-(4-methoxyphenyl)-2-[[(2S)-2-[(2-morpholin-4-ylacetyl)amino]propanoyl]amino]propanamide
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C32H48N4O8
  1
1
IC50 > 10000 nM
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CP0431917
 Compound Info 
(2S)-N-[(2S)-3-(1,2,3,4,4a,5,6,7,8,8a-decahydronaphthalen-2-yl)-1-[(2R)-2-methyloxiran-2-yl]-1-oxopropan-2-yl]-3-(4-methoxyphenyl)-2-[[(2S)-2-[(2-morpholin-4-ylacetyl)amino]propanoyl]amino]propanamide
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C35H52N4O7
  1
1
IC50 > 10000 nM
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CP0455539
 Compound Info 
(2S)-N-[(2S)-3-(2-bicyclo[2.2.1]heptanyl)-1-[(2R)-2-methyloxiran-2-yl]-1-oxopropan-2-yl]-3-(4-methoxyphenyl)-2-[[(2S)-2-[(2-morpholin-4-ylacetyl)amino]propanoyl]amino]propanamide
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C32H46N4O7
  1
1
IC50 > 10000 nM
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CP0476380
 Compound Info 
N-[(2S)-1-[[(2S)-1-[[(E,2S)-1-[4-(aminomethyl)phenyl]-4-methylsulfonylbut-3-en-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-3-(4-cyclohexylcyclohexyl)-1-oxopropan-2-yl]-2-methyl-1,3-thiazole-5-carboxamide
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C38H57N5O5S2
  1
1
IC50 > 10000 nM
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CP0476385
 Compound Info 
(2S)-N-[(1S)-1-cyclohexyl-2-[(2R)-2-methyloxiran-2-yl]-2-oxoethyl]-3-(4-methoxyphenyl)-2-[[(2S)-2-[(2-morpholin-4-ylacetyl)amino]propanoyl]amino]propanamide
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C30H44N4O7
  1
1
IC50 > 10000 nM
 Bioactivity Info 
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CP0476388
 Compound Info 
(2S)-N-[(2S)-3-(4,4-difluorocyclohexyl)-1-[(2R)-2-methyloxiran-2-yl]-1-oxopropan-2-yl]-3-(4-methoxyphenyl)-2-[[(2S)-2-[(2-morpholin-4-ylacetyl)amino]propanoyl]amino]propanamide
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C31H44F2N4O7
  1
1
IC50 > 10000 nM
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CP0476390
 Compound Info 
(2S)-N-[(2S)-4-cyclohexyl-1-[(2R)-2-methyloxiran-2-yl]-1-oxobutan-2-yl]-3-(4-methoxyphenyl)-2-[[(2S)-2-[(2-morpholin-4-ylacetyl)amino]propanoyl]amino]propanamide
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C32H48N4O7
  1
1
IC50 > 10000 nM
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CP0552317
 Compound Info 
(2S)-3-(4-methoxyphenyl)-N-[(2S)-1-[(2R)-2-methyloxiran-2-yl]-1-oxo-3-[4-(trifluoromethyl)cyclohexyl]propan-2-yl]-2-[[(2S)-2-[(2-morpholin-4-ylacetyl)amino]propanoyl]amino]propanamide
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C32H45F3N4O7
  1
1
IC50 > 10000 nM
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CP0563687
 Compound Info 
N-[(2S)-3-(1,2,3,4,4a,5,6,7,8,8a-decahydronaphthalen-1-yl)-1-[[(2S)-1-[[(E,2S)-1-[4-(aminomethyl)phenyl]-4-methylsulfonylbut-3-en-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-1-oxopropan-2-yl]-2-methyl-1,3-thiazole-5-carboxamide
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C36H53N5O5S2
  1
1
IC50 = 48040 nM
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CP0411613
 Compound Info 
N-[(2R)-1-[[(2S)-1-[[(2S)-3-cyclohexyl-1-[(2R)-2-methyloxiran-2-yl]-1-oxopropan-2-yl]amino]-3-(4-methoxyphenyl)-1-oxopropan-2-yl]amino]-1-oxopropan-2-yl]-3-methyl-1H-indene-2-carboxamide
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C36H45N3O6
  1
1
IC50 > 100000 nM
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CP0847941
 Compound Info 
N-((R)-1-((S)-3-(1H-indol-3-yl)-1-((S)-1-((R)-2-methyloxiran-2-yl)-1-oxo-3-phenylpropan-2-ylamino)-1-oxopropan-2-ylamino)-1-oxopropan-2-yl)-3-methyl-1H-indene-2-carboxamide
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C37H38N4O5
  1
1
IC50 > 100000 nM
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CP0850423
 Compound Info 
N-((R)-1-((S)-3-(1H-indol-3-yl)-1-((S)-4-(methylsulfonyl)-1-phenylbut-3-en-2-ylamino)-1-oxopropan-2-ylamino)-1-oxopropan-2-yl)-3-methyl-1H-indene-2-carboxamide
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C36H38N4O5S
  1
1
IC50 > 100000 nM
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CP0868641
 Compound Info 
N-((R)-1-((S)-1-((S)-3-cyclohexyl-1-((R)-2-methyloxiran-2-yl)-1-oxopropan-2-ylamino)-3-(1H-indol-3-yl)-1-oxopropan-2-ylamino)-1-oxopropan-2-yl)-3-methyl-1H-indene-2-carboxamide
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C37H44N4O5
  1
1
IC50 > 100000 nM
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CP0446751
 Compound Info 
N-[(2S)-1-[[(2S)-1-[[(E,2S)-1-[4-(aminomethyl)phenyl]-4-methylsulfonylbut-3-en-2-yl]amino]-3-methoxy-1-oxopropan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]-2-methyl-1,3-thiazole-5-carboxamide
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C27H39N5O6S2
  1
1
IC50 > 1000 nM
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CP0479603
 Compound Info 
N-[(2S)-1-[[(2S)-1-[[(E,2S)-1-[4-(aminomethyl)phenyl]-4-methylsulfonylbut-3-en-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-3-(4-methoxycyclohexyl)-1-oxopropan-2-yl]-2-methyl-1,3-thiazole-5-carboxamide
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C33H49N5O6S2
  1
1
IC50 > 1000 nM
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