Brief Information of the Cell Line and Protein
Cell Line ID: CL000186 , RPMI-8226
 Cell Line Info 
Synonyms
RPMI 8226
RPMI.8226
RPMI8226
RPMI no. 8226
RPMI no 8226
RPMI #8226
8226
RPMI 8226/S
RPMI-8226S
RPMI8226/S
8226/S
Roswell Park Memorial Institute 8226
GM02132
GM2132
GM 2132
GM02132C
Simpson
Category Cancer cell line
Organism
Homo sapiens (Human)
Cellosaurus ID
CVCL_0014
Protein ID: PT02585 , Proteasome subunit beta type-5
 Protein Info 
Gene Name PSMB5
Organism Homo sapiens, Human
Protein Classification Enzyme
Uniprot ID P28074
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000186
 Cell Line Info 
 Protein ID: PT02585
 Protein Info 
 
Compound ID Compound Name Compound Formula
CP0482909
 Compound Info 
(2S)-N-[(2S)-3-(4-cyclohexylcyclohexyl)-1-[[(2S)-1-[[(2S)-1-[(2R)-2-methyloxiran-2-yl]-1-oxopropan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]amino]-1-oxopropan-2-yl]-4-methyl-2-[(2-morpholin-4-ylacetyl)amino]pentanamide
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C42H65N5O7
  2
1
IC50 = 274 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
2
IC50 > 100000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0261361
 Compound Info 
(2S)-N-[(2S)-1-[[(E,2S)-1-[4-(aminomethyl)phenyl]-4-methylsulfonylbut-3-en-2-yl]amino]-4-methyl-1-oxopentan-2-yl]-2-[[(2S)-2-azido-3-phenylpropanoyl]amino]-4-methylpentanamide
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C33H47N7O5S
  1
1
IC50 = 1200 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0128289
 Compound Info 
(2S)-N-[(E,2S)-1-[4-(aminomethyl)phenyl]-4-methylsulfonylbut-3-en-2-yl]-2-[[(2S)-3-(4-aminophenyl)-2-[[(2S)-2-azido-3-phenylpropanoyl]amino]propanoyl]amino]-4-methylpentanamide
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C36H46N8O5S
  1
1
IC50 = 7200 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0427459
 Compound Info 
N-[(2S)-1-[[(2S)-1-[[(E,2S)-1-[4-(aminomethyl)phenyl]-4-methylsulfonylbut-3-en-2-yl]amino]-3-hydroxy-1-oxopropan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]-3-hydroxy-2-methylbenzamide
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C28H38N4O7S
  1
1
IC50 = 15000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0065810
 Compound Info 
(2S)-2-[[(2S)-3-[4-(aminomethyl)phenyl]-2-[[(2S)-2-azido-3-phenylpropanoyl]amino]propanoyl]amino]-N-[(E,2S)-1-[4-(aminomethyl)phenyl]-4-methylsulfonylbut-3-en-2-yl]-4-methylpentanamide
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C37H48N8O5S
  1
1
IC50 = 27000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0427458
 Compound Info 
N-[(2S)-1-[[(2S)-1-[[(2S)-5-(diaminomethylideneamino)-1-[(2R)-2-methyloxiran-2-yl]-1-oxopentan-2-yl]amino]-3-hydroxy-1-oxopropan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]-3-hydroxy-2-methylbenzamide
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C25H38N6O7
  1
1
IC50 > 30000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS