Brief Information of the Cell Line and Protein
Cell Line ID: CL000134 , DLD-1
Synonyms
DLD 1
DLD1
CoCL3
Category Cancer cell line
Organism
Homo sapiens (Human)
Cellosaurus ID
CVCL_0248
Protein ID: PT06210 , Krueppel-like factor 5
Gene Name KLF5
Organism Homo sapiens, Human
Protein Classification Transcription factor
Uniprot ID Q13887
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000134  Protein ID: PT06210
 
Compound ID Compound Name Compound Formula
CP0961810
(E)-3-(3-chlorophenyl)-N-(2-((1,1-dioxidotetrahydro-2H-thiopyran-4-yl)(methyl)amino)-2-oxoethyl)acrylamide
   Show/Hide
C17H21ClN2O4S
 1
1
IC50 = 54 nM
   TI
   LI
   LO
   TS
CP0904102
3-(3-chlorophenyl)-N-[2-[(1,1-dioxothian-4-yl)-ethyl-amino]-2-oxo-ethyl]prop-2-enamide
   Show/Hide
C18H23ClN2O4S
 1
1
IC50 = 72 nM
   TI
   LI
   LO
   TS
CP0417378
(E)-3-(3-nitrophenyl)-2-propenoic acid [2-[(1,1-dioxo-3-thiolanyl)-methylamino]-2-oxoethyl] ester
   Show/Hide
C16H18N2O7S
 1
1
IC50 = 270 nM
   TI
   LI
   LO
   TS
CP0904100
N-[2-[(1,1-dioxothiolan-3-yl)-methyl-amino]-2-oxo-ethyl]-3-(3-nitrophenyl)prop-2-enamide
   Show/Hide
C16H19N3O6S
 1
1
IC50 = 3100 nM
   TI
   LI
   LO
   TS
CP0887782
3-(3-chlorophenyl)-N-[2-[(1,1-dioxothiolan-3-yl)-methyl-amino]-2-oxo-ethyl]prop-2-enamide
   Show/Hide
C16H19ClN2O4S
 1
1
IC50 = 5300 nM
   TI
   LI
   LO
   TS
CP0887784
N-[2-[[2-[(1,1-dioxothian-4-yl)-methyl-amino]-2-oxo-ethyl]amino]-2-oxo-ethyl]benzamide
   Show/Hide
C17H23N3O5S
 1
1
IC50 = 20490 nM
   TI
   LI
   LO
   TS
CP0952931
3-[3-(dimethylsulfamoyl)phenyl]-N-[2-[(1,1-dioxothian-4-yl)-methyl-amino]-2-oxo-ethyl]prop-2-enamide
   Show/Hide
C19H27N3O6S2
 1
1
IC50 = 59000 nM
   TI
   LI
   LO
   TS
CP0853190
(2R)-2-[[3-(3-chlorophenyl)prop-2-enoyl]amino]-N-(1,1-dioxothiolan-3-yl)propanamide
   Show/Hide
C16H19ClN2O4S
 1
1
IC50 > 100000 nM
   TI
   LI
   LO
   TS
CP0853191
(2R)-2-[[3-(3-chlorophenyl)prop-2-enoyl]amino]-N-(1,1-dioxothiolan-3-yl)-N-methyl-propanamide
   Show/Hide
C17H21ClN2O4S
 1
1
IC50 > 100000 nM
   TI
   LI
   LO
   TS
CP0853192
N-[2-[(1,1-dioxothian-4-yl)-methyl-amino]-2-oxo-ethyl]-1H-indole-6-carboxamide
   Show/Hide
C17H21N3O4S
 1
1
IC50 > 100000 nM
   TI
   LI
   LO
   TS
CP0853193
6-chloro-N-[2-[(1,1-dioxothian-4-yl)-methyl-amino]-2-oxo-ethyl]quinoline-3-carboxamide
   Show/Hide
C18H20ClN3O4S
 1
1
IC50 > 100000 nM
   TI
   LI
   LO
   TS
CP0853259
3-[[3-(3-chlorophenyl)prop-2-enoyl]amino]-N-(1,1-dioxothiolan-3-yl)propanamide
   Show/Hide
C16H19ClN2O4S
 1
1
IC50 > 100000 nM
   TI
   LI
   LO
   TS
CP0874614
2-[(2,4-dibromophenyl)carbamoylamino]-N-(1,1-dioxothian-4-yl)-N-methyl-acetamide
   Show/Hide
C15H19Br2N3O4S
 1
1
IC50 > 100000 nM
   TI
   LI
   LO
   TS
CP0874615
N-[2-[(1,1-dioxothian-4-yl)-methyl-amino]-2-oxo-ethyl]-2-(4-methoxyphenyl)acetamide
   Show/Hide
C17H24N2O5S
 1
1
IC50 > 100000 nM
   TI
   LI
   LO
   TS
CP0887786
N-(1,1-dioxothian-4-yl)-2-[(3-methoxyphenyl)methylcarbamoylamino]-N-methyl-acetamide
   Show/Hide
C17H25N3O5S
 1
1
IC50 > 100000 nM
   TI
   LI
   LO
   TS
CP0904101
N-[2-[(1,1-dioxothian-4-yl)-methyl-amino]-2-oxo-ethyl]-1-(p-tolyl)cyclopropanecarboxamide
   Show/Hide
C19H26N2O4S
 1
1
IC50 > 100000 nM
   TI
   LI
   LO
   TS
CP0947234
3-(3-chlorophenyl)-N-[2-[(1,1-dioxothian-4-yl)amino]-2-oxo-ethyl]prop-2-enamide
   Show/Hide
C16H19ClN2O4S
 1
1
IC50 > 100000 nM
   TI
   LI
   LO
   TS
CP0947235
2-[(2-benzyloxyacetyl)amino]-N-(1,1-dioxothian-4-yl)-N-methyl-acetamide
   Show/Hide
C17H24N2O5S
 1
1
IC50 > 100000 nM
   TI
   LI
   LO
   TS
CP0951404
3-[3-(dimethylsulfamoyl)phenyl]-N-[2-[(1,1-dioxothiolan-3-yl)-methyl-amino]-2-oxo-ethyl]prop-2-enamide
   Show/Hide
C18H25N3O6S2
 1
1
IC50 > 100000 nM
   TI
   LI
   LO
   TS
CP0951405
2-(1,3-benzodioxol-5-yl)-N-[2-[(1,1-dioxothian-4-yl)-methyl-amino]-2-oxo-ethyl]acetamide
   Show/Hide
C17H22N2O6S
 1
1
IC50 > 100000 nM
   TI
   LI
   LO
   TS
CP0953864
N-[2-[(1,1-dioxothian-4-yl)-methyl-amino]-2-oxo-ethyl]thiophene-3-carboxamide
   Show/Hide
C13H18N2O4S2
 1
1
IC50 > 100000 nM
   TI
   LI
   LO
   TS
CP0954621
N-[2-[(1,1-dioxothian-4-yl)-methyl-amino]-2-oxo-ethyl]benzofuran-2-carboxamide
   Show/Hide
C17H20N2O5S
 1
1
IC50 > 100000 nM
   TI
   LI
   LO
   TS
CP0954622
N-[2-[(1,1-dioxothian-4-yl)-methyl-amino]-2-oxo-ethyl]chromane-2-carboxamide
   Show/Hide
C18H24N2O5S
 1
1
IC50 > 100000 nM
   TI
   LI
   LO
   TS
CP0954623
N-[2-[(1,1-dioxothian-4-yl)-methyl-amino]-2-oxo-ethyl]-1,3-benzothiazole-6-carboxamide
   Show/Hide
C16H19N3O4S2
 1
1
IC50 > 100000 nM
   TI
   LI
   LO
   TS
CP0958100
(2R)-2-[[3-(3-chlorophenyl)prop-2-enoyl]amino]-N-(1,1-dioxothian-4-yl)propanamide
   Show/Hide
C17H21ClN2O4S
 1
1
IC50 > 100000 nM
   TI
   LI
   LO
   TS
CP0958101
5-chloro-N-[2-[(1,1-dioxothian-4-yl)-methyl-amino]-2-oxo-ethyl]-1H-indole-2-carboxamide
   Show/Hide
C17H20ClN3O4S
 1
1
IC50 > 100000 nM
   TI
   LI
   LO
   TS
CP0958103
N-[2-[(1,1-dioxothian-4-yl)-methyl-amino]-2-oxo-ethyl]quinoline-2-carboxamide
   Show/Hide
C18H21N3O4S
 1
1
IC50 > 100000 nM
   TI
   LI
   LO
   TS
CP0960320
N-[2-[(1,1-dioxothian-4-yl)-methyl-amino]-2-oxo-ethyl]-2-phenyl-pyrazole-3-carboxamide
   Show/Hide
C18H22N4O4S
 1
1
IC50 > 100000 nM
   TI
   LI
   LO
   TS
CP0961811
N-[2-[(1,1-dioxothian-4-yl)-methyl-amino]-2-oxo-ethyl]-2,3-dihydro-1,4-benzodioxine-5-carboxamide
   Show/Hide
C17H22N2O6S
 1
1
IC50 > 100000 nM
   TI
   LI
   LO
   TS
CP0964031
(2R)-2-[[3-(3-chlorophenyl)prop-2-enoyl]amino]-N-(1,1-dioxothian-4-yl)-N-methyl-propanamide
   Show/Hide
C18H23ClN2O4S
 1
1
IC50 > 100000 nM
   TI
   LI
   LO
   TS
CP0964032
N-[2-[(1,1-dioxothian-4-yl)-methyl-amino]-2-oxo-ethyl]-4-oxo-chromene-3-carboxamide
   Show/Hide
C18H20N2O6S
 1
1
IC50 > 100000 nM
   TI
   LI
   LO
   TS
CP0970137
3-[[3-(3-chlorophenyl)prop-2-enoyl]amino]-N-(1,1-dioxothiolan-3-yl)-N-methyl-propanamide
   Show/Hide
C17H21ClN2O4S
 1
1
IC50 > 100000 nM
   TI
   LI
   LO
   TS
CP0970138
N-(1,1-dioxothian-4-yl)-N-methyl-2-(1-naphthylsulfonylamino)acetamide
   Show/Hide
C18H22N2O5S2
 1
1
IC50 > 100000 nM
   TI
   LI
   LO
   TS
CP0946472
3-(3-chlorophenyl)-N-[2-[cyclopropyl-(1,1-dioxothian-4-yl)amino]-2-oxo-ethyl]prop-2-enamide
   Show/Hide
C19H23ClN2O4S
 1
1
IC50 >= 7800 nM
   TI
   LI
   LO
   TS