Brief Information of the Cell Line and Protein
Cell Line ID: CL000131 , HEK293-F
Synonyms
HEK-293-F
HEK 293-F
HEK-293F
HEK293F
293-F
293 F
293F
Category Transformed cell line
Organism
Homo sapiens (Human)
Cellosaurus ID
CVCL_6642
Protein ID: PT06562 , Endothelial lipase
Gene Name LIPG
Organism Mus musculus, Mouse
Protein Classification Enzyme
Uniprot ID Q9WVG5
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000131  Protein ID: PT06562
 
Compound ID Compound Name Compound Formula
CP0061225
2-benzylsulfonyl-N-[2-(cyclopropylamino)-2-oxoethyl]-2-[6-(6-fluoropyridin-3-yl)-1,3-benzothiazol-2-yl]acetamide
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C26H23FN4O4S2
 1
1
IC50 = 94 nM
   TI
   LI
   LO
   TS
CP0405325
N-[4-(3,4-dichlorophenyl)butan-2-yl]-1-ethyl-4-hydroxy-5-oxo-2H-pyrrole-3-carboxamide
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C17H20Cl2N2O3
 1
1
IC50 = 100 nM
   TI
   LI
   LO
   TS
CP0323368
2-methylsulfonyl-2-(6-phenyl-1,3-benzothiazol-2-yl)-N-(2-sulfamoylethyl)acetamide
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C18H19N3O5S3
 1
1
IC50 = 100 nM
   TI
   LI
   LO
   TS
CP0126236
N-[2-(cyclopropylamino)-2-oxoethyl]-2-[6-(6-fluoropyridin-3-yl)-1,3-benzothiazol-2-yl]-2-(2-methoxyethylsulfonyl)acetamide
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C22H23FN4O5S2
 1
1
IC50 = 120 nM
   TI
   LI
   LO
   TS
CP0066473
US8987314, B34
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C21H28N6O6S3
 1
1
IC50 = 190 nM
   TI
   LI
   LO
   TS
CP0127616
US8987314, B3
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C17H17FN4O5S3
 1
1
IC50 = 200 nM
   TI
   LI
   LO
   TS
CP0259244
N-[(cyclopropyl- carbamoyl) methyl]-2-[6-(6- fluoropyridin-3- yl)-1,3- benzothiazol- 2-yl]-2- methanesulfonyl- acetamide
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C20H19FN4O4S2
 1
1
IC50 = 290 nM
   TI
   LI
   LO
   TS
CP0120856
US8987314, B101
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C23H26N4O7S3
 1
1
IC50 = 320 nM
   TI
   LI
   LO
   TS
CP0126235
N-[(cyclopropyl- carbamoyl) methyl]-2-[6-(6- fluoropyridin-3- yl)-1,3- benzothiazol- 2-yl]-2-(3,3,3- trifluoropropane- sulfonyl)acetamide
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C22H20F4N4O4S2
 1
1
IC50 = 600 nM
   TI
   LI
   LO
   TS