| Compound ID |
Compound Name |
Compound Formula |
|
CP0012129
|
INCB-018424
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|
C17H18N6
|
2
|
| 1 |
EC50 = 3800 nM
|
|
|
| 2 |
IC50 = 0.4 nM
|
|
|
|
CP0899214
|
3-Cyclopentyl-3-(4-(2-((4-(Piperidin-4-yl)Phenyl)Amino)-7H-Pyrrolo[2,3-d]Pyrimidin-4-yl)-1H-Pyrazol-1-yl)Propanenitrile
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|
C28H32N8
|
1
|
| 1 |
IC50 < 0.05 nM
|
|
|
|
CP0899213
|
(S)-3-Cyclopentyl-3-(4-(2-((4-(Piperidin-4-yl)Phenyl)Amino)-7H-Pyrrolo[2,3-d]Pyrimidin-4-yl)-1H-Pyrazol-1-yl)Propanenitrile
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|
C28H32N8
|
1
|
| 1 |
IC50 = 0.099 nM
|
|
|
|
CP0421618
|
3-[4-[2-(4-piperidin-4-ylanilino)-7H-pyrrolo[2,3-d]pyrimidin-4-yl]pyrazol-1-yl]propanenitrile
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|
C23H24N8
|
1
|
| 1 |
IC50 = 0.13 nM
|
|
|
|
CP0962034
|
(R)-3-Cyclopentyl-3-(4-(2-((4-(Piperidin-4-yl)Phenyl)Amino)-7H-Pyrrolo[2,3-d]Pyrimidin-4-yl)-1H-Pyrazol-1-yl)Propanenitrile
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|
C28H32N8
|
1
|
| 1 |
IC50 = 0.15 nM
|
|
|
|
CP0421546
|
4-(1-but-3-enylpyrazol-4-yl)-N-(4-piperidin-4-ylphenyl)-7H-pyrrolo[2,3-d]pyrimidin-2-amine
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|
C24H27N7
|
1
|
| 1 |
IC50 = 0.26 nM
|
|
|
|
CP0013326
|
BARICITINIB
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|
C16H17N7O2S
|
1
|
| 1 |
IC50 = 0.29 nM
|
|
|
|
CP0043616
|
N-tert-butyl-3-[[5-methyl-2-[4-(2-pyrrolidin-1-ylethoxy)anilino]pyrimidin-4-yl]amino]benzenesulfonamide
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|
C27H36N6O3S
|
1
|
| 1 |
IC50 = 0.75 nM
|
|
|
|
CP0869724
|
SID103905273
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|
C17H18N6
|
1
|
| 1 |
IC50 = 0.92 nM
|
|
|
|
CP0002393
|
3-((3R,4R)-4-methyl-3-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)piperidin-1-yl)-3-oxopropanenitrile
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|
C16H20N6O
|
1
|
| 1 |
IC50 = 2.9 nM
|
|
|
|
CP0552149
|
4-N-(1-tert-butylsulfonyl-2,3-dihydroindol-6-yl)-2-N-[3-fluoro-4-(1-methylpiperidin-4-yl)phenyl]-5-methylpyrimidine-2,4-diamine
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|
C29H37FN6O2S
|
1
|
| 1 |
IC50 = 3.6 nM
|
|
|
|
CP0954265
|
S-RUXOLITINIB
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|
C17H18N6
|
1
|
| 1 |
IC50 = 5 nM
|
|
|
|
CP0562931
|
N-[2-fluoro-5-[[2-[3-fluoro-4-(1-methylpiperidin-4-yl)anilino]-5-methylpyrimidin-4-yl]amino]phenyl]-2-methylpropane-2-sulfonamide
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|
C27H34F2N6O2S
|
1
|
| 1 |
IC50 = 6.5 nM
|
|
|
|
CP0552148
|
N-[5-[[2-[3,5-difluoro-4-(1-methylpiperidin-4-yl)anilino]-5-methylpyrimidin-4-yl]amino]-2-fluorophenyl]-2-methylpropane-2-sulfonamide
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|
C27H33F3N6O2S
|
1
|
| 1 |
IC50 = 8.2 nM
|
|
|
|
CP0534037
|
4-[[4-[3-(tert-butylsulfonylamino)-4-chloroanilino]-5-methylpyrimidin-2-yl]amino]-2-fluoro-N-(1-methylpiperidin-4-yl)benzamide
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|
C28H35ClFN7O3S
|
1
|
| 1 |
IC50 = 11.4 nM
|
|
|
