Brief Information of the Compound and Protein
Compound Name
N-[5-[[2-[3,5-difluoro-4-(1-methylpiperidin-4-yl)anilino]-5-methylpyrimidin-4-yl]amino]-2-fluorophenyl]-2-methylpropane-2-sulfonamide
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PubChem ID
CID: 149370917
Canonical SMILES
CN1CCC(CC1)c1c(F)cc(Nc2ncc(C)c(Nc3ccc(F)c(NS(=O)(=O)C(C)(C)C)c3)n2)cc1F
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Compound Formula C27H33F3N6O2S
Compound Structure
Protein Name
Tyrosine-protein kinase JAK2
Protein Classification
Enzyme
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Kinase
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Protein Kinase
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TK protein kinase group
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Tyrosine protein kinase JakB family
Uniprot ID
O60674
Gene Name
JAK2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000131 HEK293-F Homo sapiens (Human)  1
1
IC50 = 8.2 nM
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