Brief Information of the Cell Line and Protein
Cell Line ID: CL000121 , FDC-P1
Synonyms
FDCP-1
FDCP1
Factor Dependent Continuous-Paterson 1
Factor Dependent Cell-Paterson 1
Category Factor-dependent cell line
Organism
Mus musculus (Mouse)
Cellosaurus ID
CVCL_2039
Protein ID: PT01217 , Bcl-2-like protein 1
Gene Name BCL2L1
Organism Homo sapiens, Human
Protein Classification Ion channel
Uniprot ID Q07817
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000121  Protein ID: PT01217
 
Compound ID Compound Name Compound Formula
CP0112166
4-[4-[[2-(4-chlorophenyl)-6-[2-(dimethylamino)ethoxy]phenyl]methyl]piperazin-1-yl]-N-[4-[[(2R)-4-morpholin-4-yl-1-phenylsulfanylbutan-2-yl]amino]-3-(trifluoromethylsulfonyl)phenyl]sulfonylbenzamide
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C49H56ClF3N6O7S3
 1
1
IC50 = 33 nM
   TI
   LI
   LO
   TS
CP0068147
(R)-4-(4-((2-(4-chlorophenyl)-5,5-dimethylcyclohex-1-enyl)methyl)piperazin-1-yl)-N-(4-(4-morpholino-1-(phenylthio)butan-2-ylamino)-3-(trifluoromethylsulfonyl)phenylsulfonyl)benzamide
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C47H55ClF3N5O6S3
 1
1
IC50 = 60 nM
   TI
   LI
   LO
   TS
CP0281357
4-[4-[[2-(4-chlorophenyl)phenyl]methyl]piperazin-1-yl]-N-[4-[[(2R)-4-morpholin-4-yl-1-phenylsulfanylbutan-2-yl]amino]-3-(trifluoromethylsulfonyl)phenyl]sulfonylbenzamide
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C45H47ClF3N5O6S3
 1
1
IC50 = 64 nM
   TI
   LI
   LO
   TS
CP0116815
4-[4-[[2-(4-chlorophenyl)-5-[2-(dimethylamino)ethoxy]phenyl]methyl]piperazin-1-yl]-N-[4-[[(2R)-4-morpholin-4-yl-1-phenylsulfanylbutan-2-yl]amino]-3-(trifluoromethylsulfonyl)phenyl]sulfonylbenzamide
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C49H56ClF3N6O7S3
 1
1
IC50 = 138 nM
   TI
   LI
   LO
   TS
CP0311689
4-[4-[[2-(4-chlorophenyl)-6-[2-(dimethylamino)-2-oxoethoxy]phenyl]methyl]piperazin-1-yl]-N-[4-[[(2R)-4-morpholin-4-yl-1-phenylsulfanylbutan-2-yl]amino]-3-(trifluoromethylsulfonyl)phenyl]sulfonylbenzamide
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C49H54ClF3N6O8S3
 1
1
IC50 = 226 nM
   TI
   LI
   LO
   TS
CP0264536
4-[4-[(R)-[2-(4-chlorophenyl)phenyl]sulfinyl]piperidin-1-yl]-N-[4-[[(2R)-4-morpholin-4-yl-1-phenylsulfanylbutan-2-yl]amino]-3-(trifluoromethylsulfonyl)phenyl]sulfonylbenzamide
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C45H46ClF3N4O7S4
 1
1
IC50 = 1720 nM
   TI
   LI
   LO
   TS
CP0054087
2-[4-[[2-(4-chlorophenyl)phenyl]methyl]piperazin-1-yl]-N-[4-[[(2R)-4-morpholin-4-yl-1-phenylsulfanylbutan-2-yl]amino]-3-(trifluoromethylsulfonyl)phenyl]sulfonylpyrimidine-5-carboxamide
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C43H45ClF3N7O6S3
 1
1
IC50 = 2090 nM
   TI
   LI
   LO
   TS
CP0115928
4-[4-[[2-(4-chlorophenyl)-5-[2-(dimethylamino)-2-oxoethoxy]phenyl]methyl]piperazin-1-yl]-N-[4-[[(2R)-4-morpholin-4-yl-1-phenylsulfanylbutan-2-yl]amino]-3-(trifluoromethylsulfonyl)phenyl]sulfonylbenzamide
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C49H54ClF3N6O8S3
 1
1
IC50 = 2090 nM
   TI
   LI
   LO
   TS
CP0115927
4-[4-[[2-(4-chlorophenyl)phenyl]methyl]-4-cyanopiperidin-1-yl]-N-[4-[[(2R)-4-morpholin-4-yl-1-phenylsulfanylbutan-2-yl]amino]-3-(trifluoromethylsulfonyl)phenyl]sulfonylbenzamide
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C47H47ClF3N5O6S3
 1
1
IC50 = 2820 nM
   TI
   LI
   LO
   TS