Brief Information of the Cell Line and Protein
Cell Line ID: CL000111 , MDA-MB-231
 Cell Line Info 
Synonyms
MDA_MB_231
MDA-MB 231
MDA.MB.231
MDA MB 231
MDA MB231
MDA Mb231
MDA-MB231
MDAMB-231
MDAMB231
MDA-231
MDA-231P
MDA231
MDA231-BRE
MB231
MD Anderson-Metastatic Breast-231
Category Cancer cell line
Organism
Homo sapiens (Human)
Cellosaurus ID
CVCL_0062
Protein ID: PT04124 , Proteinase-activated receptor 2
 Protein Info 
Gene Name F2RL1
Organism Homo sapiens, Human
Protein Classification Membrane receptor
Uniprot ID P55085
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000111
 Cell Line Info 
 Protein ID: PT04124
 Protein Info 
 
Compound ID Compound Name Compound Formula
CP0427040
 Compound Info 
4-[4-[6-(4-fluorophenyl)-8-propan-2-ylimidazo[1,2-b]pyridazine-2-carbonyl]-3,3-dimethylpiperazin-1-yl]-4-oxobutanoic acid
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C26H30FN5O4
  1
1
IC50 = 480 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0490851
 Compound Info 
4-[4-[6-(4-fluorophenyl)-8-propan-2-ylimidazo[1,2-b]pyridazine-2-carbonyl]-3,3-dimethylpiperazin-1-yl]-N-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[4-(methoxymethyl)triazol-1-yl]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethyl]-4-oxobutanamide
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C52H80FN9O14
  1
1
IC50 = 860 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0484217
 Compound Info 
(2S)-N-benzyl-2-[[(2S)-2-[[1-[(2,6-dichlorophenyl)methyl]-3-(pyrrolidin-1-ylmethyl)indazol-6-yl]carbamoylamino]-3-(3,4-difluorophenyl)propanoyl]amino]-4-[3-[1-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[[4-[4-[6-(4-fluorophenyl)-8-propan-2-ylimidazo[1,2-b]pyridazine-2-carbonyl]-3,3-dimethylpiperazin-1-yl]-4-oxobutanoyl]amino]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethyl]triazol-4-yl]propanoylamino]butanamide
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C119H172Cl2F3N17O30
  1
1
IC50 = 3500 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS