Brief Information of the Cell Line and Protein
Cell Line ID: CL000111 , MDA-MB-231
Synonyms
MDA_MB_231
MDA-MB 231
MDA.MB.231
MDA MB 231
MDA MB231
MDA Mb231
MDA-MB231
MDAMB-231
MDAMB231
MDA-231
MDA-231P
MDA231
MDA231-BRE
MB231
MD Anderson-Metastatic Breast-231
Category Cancer cell line
Organism
Homo sapiens (Human)
Cellosaurus ID
CVCL_0062
Protein ID: PT01466 , Telomerase reverse transcriptase
Gene Name TERT
Organism Homo sapiens, Human
Protein Classification Enzyme
Uniprot ID O14746
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000111  Protein ID: PT01466
 
Compound ID Compound Name Compound Formula
CP0092405
2-(3-Naphthalen-2-yl-but-2-enoylamino)-benzoic acid
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C21H17NO3
 1
1
IC50 = 170 nM
   TI
   LI
   LO
   TS
CP0557097
2-[5,7-dimethoxy-4-oxo-2-(3,4,5-trimethoxyphenyl)chromen-3-yl]oxy-N-[(E)-furan-2-ylmethylideneamino]acetamide
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C27H26N2O10
 1
1
IC50 = 910 nM
   TI
   LI
   LO
   TS
CP0557096
2-[5,7-dimethoxy-4-oxo-2-(3,4,5-trimethoxyphenyl)chromen-3-yl]oxy-N-[(E)-(2-fluorophenyl)methylideneamino]acetamide
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C29H27FN2O9
 1
1
IC50 = 1820 nM
   TI
   LI
   LO
   TS
CP0478250
5,7-dimethoxy-3-(4-piperidin-1-ylbutoxy)-2-(3,4,5-trimethoxyphenyl)chromen-4-one
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C29H37NO8
 1
1
IC50 = 2000 nM
   TI
   LI
   LO
   TS
CP0659470
Ethidium bromide
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C21H20BrN3
 1
1
IC50 = 2330 nM
   TI
   LI
   LO
   TS
CP0549968
5,7-dimethoxy-3-(3-piperidin-1-ylpropoxy)-2-(3,4,5-trimethoxyphenyl)chromen-4-one
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C28H35NO8
 1
1
IC50 = 3070 nM
   TI
   LI
   LO
   TS
CP0556009
5,7-dimethoxy-3-[3-(4-methylpiperazin-1-yl)propoxy]-2-(3,4,5-trimethoxyphenyl)chromen-4-one
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C28H36N2O8
 1
1
IC50 = 19660 nM
   TI
   LI
   LO
   TS
CP0491290
5,7-dimethoxy-3-(3-pyrrolidin-1-ylpropoxy)-2-(3,4,5-trimethoxyphenyl)chromen-4-one
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C27H33NO8
 1
1
IC50 = 28910 nM
   TI
   LI
   LO
   TS
CP0391499
3-[3-(diethylamino)propoxy]-5,7-dimethoxy-2-(3,4,5-trimethoxyphenyl)chromen-4-one
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C27H35NO8
 1
1
IC50 = 35660 nM
   TI
   LI
   LO
   TS
CP0445457
3-[4-(diethylamino)butoxy]-5,7-dimethoxy-2-(3,4,5-trimethoxyphenyl)chromen-4-one
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C28H37NO8
 1
1
IC50 = 40300 nM
   TI
   LI
   LO
   TS