| Compound ID |
Compound Name |
Compound Formula |
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CP0218662
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(2S)-1-[(2S)-2-cyclohexyl-2-[[(2S)-2-(methylamino)propanoyl]amino]acetyl]-N-[(1S,2R)-2-[6-[[(1S,2R)-1-[[(2S)-1-[(2S)-2-cyclohexyl-2-[[(2S)-2-(methylamino)propanoyl]amino]acetyl]pyrrolidine-2-carbonyl]amino]-2,3-dihydro-1H-inden-2-yl]oxy]hexa-2,4-diynoxy]-2,3-dihydro-1H-inden-1-yl]pyrrolidine-2-carboxamide
Show/Hide
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C58H78N8O8
|
1
|
| 1 |
EC50 = 0.1 nM
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|
|
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CP0466252
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(2S)-1-[(2S)-2-cyclohexyl-2-[[(2S)-2-(methylamino)propanoyl]amino]acetyl]-N-[(1S,2R)-2-[6-[[(1S,2R)-1-[[(2S)-1-[(2S)-2-cyclohexyl-2-[[(2S)-2-(methylamino)propanoyl]amino]acetyl]pyrrolidine-2-carbonyl]amino]-2,3-dihydro-1H-inden-2-yl]oxy]hexoxy]-2,3-dihydro-1H-inden-1-yl]pyrrolidine-2-carboxamide
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C58H86N8O8
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1
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| 1 |
EC50 = 0.1 nM
|
|
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CP0466253
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(1S,3S,5S)-2-[(2S)-2-cyclohexyl-2-[[(2S)-2-(methylamino)propanoyl]amino]acetyl]-N-[(1S,2R)-2-[6-[[(1S,2R)-1-[[(1S,3S,5S)-2-[(2S)-2-cyclohexyl-2-[[(2S)-2-(methylamino)propanoyl]amino]acetyl]-2-azabicyclo[3.1.0]hexane-3-carbonyl]amino]-2,3-dihydro-1H-inden-2-yl]oxy]hexa-2,4-diynoxy]-2,3-dihydro-1H-inden-1-yl]-2-azabicyclo[3.1.0]hexane-3-carboxamide
Show/Hide
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C60H78N8O8
|
1
|
| 1 |
EC50 = 0.1 nM
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|
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CP0387363
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(2S)-1-[(2S)-2-cyclohexyl-2-[[(2S)-2-(methylamino)propanoyl]amino]acetyl]-N-[(1S,2S)-2-[6-[[(1S,2S)-1-[[(2S)-1-[(2S)-2-cyclohexyl-2-[[(2S)-2-(methylamino)propanoyl]amino]acetyl]pyrrolidine-2-carbonyl]amino]-2,3-dihydro-1H-inden-2-yl]oxy]hexa-2,4-diynoxy]-2,3-dihydro-1H-inden-1-yl]pyrrolidine-2-carboxamide
Show/Hide
|
C58H78N8O8
|
1
|
| 1 |
EC50 = 0.2 nM
|
|
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CP0458411
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(2S)-1-[(2S)-3,3-dimethyl-2-[[(2S)-2-(methylamino)propanoyl]amino]butanoyl]-N-[(1S,2R)-2-[6-[[(1S,2R)-1-[[(2S)-1-[(2S)-3,3-dimethyl-2-[[(2S)-2-(methylamino)propanoyl]amino]butanoyl]pyrrolidine-2-carbonyl]amino]-1,2,3,4-tetrahydronaphthalen-2-yl]oxy]hexa-2,4-diynoxy]-1,2,3,4-tetrahydronaphthalen-1-yl]pyrrolidine-2-carboxamide
Show/Hide
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C56H78N8O8
|
1
|
| 1 |
EC50 = 0.2 nM
|
|
|
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CP0462276
|
(2S)-1-[(2S)-2-cyclohexyl-2-[[(2S)-2-(methylamino)propanoyl]amino]acetyl]-N-[(4R)-1-[6-[(4R)-4-[[(2S)-1-[(2S)-2-cyclohexyl-2-[[(2S)-2-(methylamino)propanoyl]amino]acetyl]pyrrolidine-2-carbonyl]amino]-3,4-dihydro-2H-quinolin-1-yl]hexa-2,4-diynyl]-3,4-dihydro-2H-quinolin-4-yl]pyrrolidine-2-carboxamide
Show/Hide
|
C58H80N10O6
|
1
|
| 1 |
EC50 = 0.2 nM
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|
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CP0531868
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(4R)-3-[(2S)-2-cyclohexyl-2-[[(2S)-2-(methylamino)propanoyl]amino]acetyl]-N-[(1S,2R)-2-[6-[[(1S,2R)-1-[[(4R)-3-[(2S)-2-cyclohexyl-2-[[(2S)-2-(methylamino)propanoyl]amino]acetyl]-1,3-thiazolidine-4-carbonyl]amino]-2,3-dihydro-1H-inden-2-yl]oxy]hexa-2,4-diynoxy]-2,3-dihydro-1H-inden-1-yl]-1,3-thiazolidine-4-carboxamide
Show/Hide
|
C56H74N8O8S2
|
1
|
| 1 |
EC50 = 0.2 nM
|
|
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CP0458409
|
(2S)-1-[(2S)-2-cyclohexyl-2-[[(2S)-2-(methylamino)propanoyl]amino]acetyl]-N-[(1S,2R)-2-[6-[[(1S,2R)-1-[[(2S)-1-[(2S)-2-cyclohexyl-2-[[(2S)-2-(methylamino)propanoyl]amino]acetyl]-2,5-dihydropyrrole-2-carbonyl]amino]-2,3-dihydro-1H-inden-2-yl]oxy]hexa-2,4-diynoxy]-2,3-dihydro-1H-inden-1-yl]-2,5-dihydropyrrole-2-carboxamide
Show/Hide
|
C58H74N8O8
|
1
|
| 1 |
EC50 = 0.3 nM
|
|
|
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CP0266599
|
1-[6-[(4-fluorophenyl)methyl]-3,3-dimethyl-2H-pyrrolo[3,2-b]pyridin-1-yl]-2-[(2R,5R)-5-methyl-2-[[(3R)-3-methylmorpholin-4-yl]methyl]piperazin-1-yl]ethanone
Show/Hide
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C29H40FN5O2
|
2
|
| 1 |
EC50 = 0.32 nM
|
|
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| 2 |
IC50 = 0.32 nM
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CP0230298
|
(2S)-1-[(2S)-3,3-dimethyl-2-[[(2S)-2-(methylamino)propanoyl]amino]butanoyl]-N-[(1S,2R)-2-[6-[[(1S,2R)-1-[[(2S)-1-[(2S)-3,3-dimethyl-2-[[(2S)-2-(methylamino)propanoyl]amino]butanoyl]pyrrolidine-2-carbonyl]amino]-2,3-dihydro-1H-inden-2-yl]oxy]hexa-2,4-diynoxy]-2,3-dihydro-1H-inden-1-yl]pyrrolidine-2-carboxamide
Show/Hide
|
C54H74N8O8
|
1
|
| 1 |
EC50 = 0.4 nM
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CP0077521
|
(2S)-N-[(1S)-1-cyclohexyl-2-[(2S)-2-[4-(4-fluorobenzoyl)-1,3-thiazol-2-yl]pyrrolidin-1-yl]-2-oxoethyl]-2-(methylamino)propanamide
Show/Hide
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C26H33FN4O3S
|
2
|
| 1 |
EC50 = 0.4 nM
|
|
|
| 2 |
IC50 = 0.4 nM
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CP0443524
|
(4R)-3-[(2S)-3,3-dimethyl-2-[[(2S)-2-(methylamino)propanoyl]amino]butanoyl]-N-[(1S,2R)-2-[6-[[(1S,2R)-1-[[(4R)-3-[(2S)-3,3-dimethyl-2-[[(2S)-2-(methylamino)propanoyl]amino]butanoyl]-1,3-thiazolidine-4-carbonyl]amino]-2,3-dihydro-1H-inden-2-yl]oxy]hexa-2,4-diynoxy]-2,3-dihydro-1H-inden-1-yl]-1,3-thiazolidine-4-carboxamide
Show/Hide
|
C52H70N8O8S2
|
1
|
| 1 |
EC50 = 0.5 nM
|
|
|
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CP0466251
|
(2S)-1-[(2S)-2-cyclohexyl-2-[[(2S)-2-(methylamino)propanoyl]amino]acetyl]-N-[(1S,2R)-2-[2-[2-[[(1S,2R)-1-[[(2S)-1-[(2S)-2-cyclohexyl-2-[[(2S)-2-(methylamino)propanoyl]amino]acetyl]pyrrolidine-2-carbonyl]amino]-2,3-dihydro-1H-inden-2-yl]oxy]ethoxy]ethoxy]-2,3-dihydro-1H-inden-1-yl]pyrrolidine-2-carboxamide
Show/Hide
|
C56H82N8O9
|
1
|
| 1 |
EC50 = 0.6 nM
|
|
|
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CP0521709
|
(7R)-6-[(2S)-2-cyclohexyl-2-[[(2S)-2-(methylamino)propanoyl]amino]acetyl]-N-[(1S,2R)-2-[6-[[(1S,2R)-1-[[(7R)-6-[(2S)-2-cyclohexyl-2-[[(2S)-2-(methylamino)propanoyl]amino]acetyl]-4-thia-6-azaspiro[2.4]heptane-7-carbonyl]amino]-2,3-dihydro-1H-inden-2-yl]oxy]hexa-2,4-diynoxy]-2,3-dihydro-1H-inden-1-yl]-4-thia-6-azaspiro[2.4]heptane-7-carboxamide
Show/Hide
|
C60H78N8O8S2
|
1
|
| 1 |
EC50 = 0.6 nM
|
|
|
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CP0550819
|
(2S)-1-[(2S)-3,3-dimethyl-2-[[(2S)-2-(methylamino)propanoyl]amino]butanoyl]-N-[(1S,2S)-2-[6-[[(1S,2S)-1-[[(2S)-1-[(2S)-3,3-dimethyl-2-[[(2S)-2-(methylamino)propanoyl]amino]butanoyl]pyrrolidine-2-carbonyl]amino]-1,2,3,4-tetrahydronaphthalen-2-yl]oxy]hexa-2,4-diynoxy]-1,2,3,4-tetrahydronaphthalen-1-yl]pyrrolidine-2-carboxamide
Show/Hide
|
C56H78N8O8
|
1
|
| 1 |
EC50 = 0.6 nM
|
|
|
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CP0381601
|
(2S)-1-[(2S)-3,3-dimethyl-2-[[(2S)-2-(methylamino)propanoyl]amino]butanoyl]-N-[(1R,2R)-2-[6-[[(1R,2R)-1-[[(2S)-1-[(2S)-3,3-dimethyl-2-[[(2S)-2-(methylamino)propanoyl]amino]butanoyl]pyrrolidine-2-carbonyl]amino]-1,2,3,4-tetrahydronaphthalen-2-yl]oxy]hexa-2,4-diynoxy]-1,2,3,4-tetrahydronaphthalen-1-yl]pyrrolidine-2-carboxamide
Show/Hide
|
C56H78N8O8
|
1
|
| 1 |
EC50 = 2 nM
|
|
|
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CP0461252
|
(2S)-1-[(2S)-3-methyl-2-[[(2S)-2-(methylamino)propanoyl]amino]butanoyl]-N-[(1S,2R)-2-[6-[[(1S,2R)-1-[[(2S)-1-[(2S)-3-methyl-2-[[(2S)-2-(methylamino)propanoyl]amino]butanoyl]pyrrolidine-2-carbonyl]amino]-2,3-dihydro-1H-inden-2-yl]oxy]hexa-2,4-diynoxy]-2,3-dihydro-1H-inden-1-yl]pyrrolidine-2-carboxamide
Show/Hide
|
C52H70N8O8
|
1
|
| 1 |
EC50 = 2 nM
|
|
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CP0547913
|
1-[[(2R,5R)-1-[2-[6-[(4-fluorophenyl)methyl]-3,3-dimethyl-2H-pyrrolo[3,2-b]pyridin-1-yl]-2-oxoethyl]-5-methylpiperazin-2-yl]methyl]pyrrolidin-2-one
Show/Hide
|
C28H36FN5O2
|
1
|
| 1 |
EC50 = 2.3 nM
|
|
|
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CP0122118
|
US9018214, 199
Show/Hide
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C28H35F2N5O2
|
1
|
| 1 |
EC50 = 2.4 nM
|
|
|
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CP0547914
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US9018214, 240
Show/Hide
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C29H40FN5O2
|
1
|
| 1 |
EC50 = 2.4 nM
|
|
|
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CP0231623
|
US9018214, 234
Show/Hide
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C28H38FN5O2
|
1
|
| 1 |
EC50 = 2.5 nM
|
|
|
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CP0461260
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N,N'-bis[(1S,2R)-1-[[(2S)-1-[(2S)-2-cyclohexyl-2-[[(2S)-2-(methylamino)propanoyl]amino]acetyl]pyrrolidine-2-carbonyl]amino]-2,3-dihydro-1H-inden-2-yl]decanediamide
Show/Hide
|
C62H92N10O8
|
1
|
| 1 |
EC50 = 3 nM
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|
|
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CP0435112
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(2S)-1-[(2S)-3,3-dimethyl-2-[[(2S)-2-(methylamino)propanoyl]amino]butanoyl]-N-[(1S,2R)-2-prop-2-ynoxy-1,2,3,4-tetrahydronaphthalen-1-yl]pyrrolidine-2-carboxamide
Show/Hide
|
C28H40N4O4
|
1
|
| 1 |
EC50 = 4 nM
|
|
|
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CP0527385
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(2S)-1-[(2S)-3,3-dimethyl-2-[[(2S)-2-(methylamino)propanoyl]amino]butanoyl]-N-[(1R,2S)-2-[6-[[(1R,2S)-1-[[(2S)-1-[(2S)-3,3-dimethyl-2-[[(2S)-2-(methylamino)propanoyl]amino]butanoyl]pyrrolidine-2-carbonyl]amino]-1,2,3,4-tetrahydronaphthalen-2-yl]oxy]hexa-2,4-diynoxy]-1,2,3,4-tetrahydronaphthalen-1-yl]pyrrolidine-2-carboxamide
Show/Hide
|
C56H78N8O8
|
1
|
| 1 |
EC50 = 4 nM
|
|
|
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CP0293714
|
(2S)-N-[(1S)-1-cyclohexyl-2-oxo-2-[[(1R,4S,6S)-2-(2-phenylethyl)-2-azabicyclo[2.2.2]octan-6-yl]amino]ethyl]-2-(methylamino)propanamide
Show/Hide
|
C27H42N4O2
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1
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| 1 |
EC50 = 5 nM
|
|
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CP0447072
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(2S)-1-[(2S)-2-cyclohexyl-2-[[(2S)-2-(methylamino)propanoyl]amino]acetyl]-N-[2-[6-[[2-[[(2S)-1-[(2S)-2-cyclohexyl-2-[[(2S)-2-(methylamino)propanoyl]amino]acetyl]pyrrolidine-2-carbonyl]amino]-1,3-dihydroindene-2-carbonyl]amino]hexa-2,4-diynylcarbamoyl]-1,3-dihydroinden-2-yl]pyrrolidine-2-carboxamide
Show/Hide
|
C60H80N10O8
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1
|
| 1 |
EC50 = 5 nM
|
|
|
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CP0327287
|
US9018214, 180
Show/Hide
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C28H37N5O2
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1
|
| 1 |
EC50 = 7.5 nM
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|
|
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CP0069638
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(2S)-1-[(2S)-3,3-dimethyl-2-[[(2S)-2-(methylamino)propanoyl]amino]butanoyl]-N-[(1S,2S)-2-prop-2-ynoxy-1,2,3,4-tetrahydronaphthalen-1-yl]pyrrolidine-2-carboxamide
Show/Hide
|
C28H40N4O4
|
1
|
| 1 |
EC50 = 10 nM
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|
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CP0381578
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(2S)-1-[(2S)-2-cyclohexyl-2-[[(2S)-2-(methylamino)propanoyl]amino]acetyl]-N-[(1S,2R)-2-[[4-[4-[[(1S,2R)-1-[[(2S)-1-[(2S)-2-cyclohexyl-2-[[(2S)-2-(methylamino)propanoyl]amino]acetyl]pyrrolidine-2-carbonyl]amino]-2,3-dihydro-1H-inden-2-yl]carbamoyl]phenyl]benzoyl]amino]-2,3-dihydro-1H-inden-1-yl]pyrrolidine-2-carboxamide
Show/Hide
|
C66H84N10O8
|
1
|
| 1 |
EC50 = 15 nM
|
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CP0566033
|
1-[[(2R,5R)-1-[2-[6-[difluoro(phenyl)methyl]-3,3-dimethyl-2H-pyrrolo[3,2-b]pyridin-1-yl]-2-oxoethyl]-5-methylpiperazin-2-yl]methyl]pyrrolidin-2-one
Show/Hide
|
C28H35F2N5O2
|
1
|
| 1 |
EC50 = 20 nM
|
|
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CP0513569
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1-[[(2R,5R)-1-[2-[6-(1,1-difluorobutyl)-3,3-dimethyl-2H-pyrrolo[3,2-b]pyridin-1-yl]-2-oxoethyl]-5-methylpiperazin-2-yl]methyl]pyrrolidin-2-one
Show/Hide
|
C25H37F2N5O2
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1
|
| 1 |
EC50 = 24 nM
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|
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CP0499345
|
(2S)-N-[(1S)-1-cyclohexyl-2-[[(3S)-1-[2-(4-fluorophenyl)ethyl]piperidin-3-yl]amino]-2-oxoethyl]-2-(methylamino)propanamide
Show/Hide
|
C25H39FN4O2
|
1
|
| 1 |
EC50 = 58 nM
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CP0397178
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(2S)-N-[(3S)-1-[2-(4-fluorophenyl)ethyl]piperidin-3-yl]-3,3-dimethyl-2-[[(2S)-2-(methylamino)propanoyl]amino]butanamide
Show/Hide
|
C23H37FN4O2
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1
|
| 1 |
EC50 = 60 nM
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CP0476484
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(2S)-3,3-dimethyl-2-[[(2S)-2-(methylamino)propanoyl]amino]-N-[(3S)-1-[2-(4-nitrophenyl)ethyl]piperidin-3-yl]butanamide
Show/Hide
|
C23H37N5O4
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1
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| 1 |
EC50 = 60 nM
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CP0523433
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(2S)-3,3-dimethyl-2-[[(2S)-2-(methylamino)propanoyl]amino]-N-[(3S)-1-[2-(4-methylphenyl)ethyl]piperidin-3-yl]butanamide
Show/Hide
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C24H40N4O2
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1
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| 1 |
EC50 = 60 nM
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CP0504124
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(2S)-N-[(3S)-1-[2-(4-hydroxyphenyl)ethyl]piperidin-3-yl]-3,3-dimethyl-2-[[(2S)-2-(methylamino)propanoyl]amino]butanamide
Show/Hide
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C23H38N4O3
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1
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| 1 |
EC50 = 68 nM
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CP0403546
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(2S)-N-[(3S)-1-[2-(4-bromophenyl)ethyl]piperidin-3-yl]-3,3-dimethyl-2-[[(2S)-2-(methylamino)propanoyl]amino]butanamide
Show/Hide
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C23H37BrN4O2
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1
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| 1 |
EC50 = 71 nM
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CP0399188
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(2S)-N-[(1S)-1-cyclohexyl-2-[[(3S)-1-[2-(2-fluorophenyl)ethyl]piperidin-3-yl]amino]-2-oxoethyl]-2-(methylamino)propanamide
Show/Hide
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C25H39FN4O2
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1
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| 1 |
EC50 = 104 nM
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CP0499346
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(2S)-N-[(1S)-1-cyclohexyl-2-oxo-2-[[(3S)-1-(2-phenylethyl)piperidin-3-yl]amino]ethyl]-2-(methylamino)propanamide
Show/Hide
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C25H40N4O2
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1
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| 1 |
EC50 = 113 nM
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CP0403547
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(2S)-N-[(3S)-1-[2-(4-chlorophenyl)ethyl]piperidin-3-yl]-3,3-dimethyl-2-[[(2S)-2-(methylamino)propanoyl]amino]butanamide
Show/Hide
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C23H37ClN4O2
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1
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| 1 |
EC50 = 117 nM
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CP0228942
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1-N,4-N-bis[(1S,2R)-1-[[(2S)-1-[(2S)-2-cyclohexyl-2-[[(2S)-2-(methylamino)propanoyl]amino]acetyl]pyrrolidine-2-carbonyl]amino]-2,3-dihydro-1H-inden-2-yl]benzene-1,4-dicarboxamide
Show/Hide
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C60H80N10O8
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1
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| 1 |
EC50 = 124 nM
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CP0258426
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(2S)-1-[(2S)-3,3-dimethyl-2-[[(2S)-2-(methylamino)propanoyl]amino]butanoyl]-N-[(1R,2S)-2-prop-2-ynoxy-1,2,3,4-tetrahydronaphthalen-1-yl]pyrrolidine-2-carboxamide
Show/Hide
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C28H40N4O4
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1
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| 1 |
EC50 = 126 nM
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CP0106277
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US9018214, 190
Show/Hide
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C24H35F2N5O2
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1
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| 1 |
EC50 = 150 nM
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CP0399187
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(2S)-N-[(3S)-1-[2-(2-methoxyphenyl)ethyl]piperidin-3-yl]-3,3-dimethyl-2-[[(2S)-2-(methylamino)propanoyl]amino]butanamide
Show/Hide
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C24H40N4O3
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1
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| 1 |
EC50 = 156 nM
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CP0522438
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(2S)-N-[(3S)-1-[2-(4-methoxyphenyl)ethyl]piperidin-3-yl]-3,3-dimethyl-2-[[(2S)-2-(methylamino)propanoyl]amino]butanamide
Show/Hide
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C24H40N4O3
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1
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| 1 |
EC50 = 158 nM
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CP0504077
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(2S)-N-[(3S)-1-[2-(3-methoxyphenyl)ethyl]piperidin-3-yl]-3,3-dimethyl-2-[[(2S)-2-(methylamino)propanoyl]amino]butanamide
Show/Hide
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C24H40N4O3
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1
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| 1 |
EC50 = 164 nM
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|
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CP0497552
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(2S)-N-[(3S)-1-[2-(1H-indol-3-yl)ethyl]piperidin-3-yl]-3,3-dimethyl-2-[[(2S)-2-(methylamino)propanoyl]amino]butanamide
Show/Hide
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C25H39N5O2
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1
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| 1 |
EC50 = 185 nM
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|
|
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CP0223574
|
US9018214, 188
Show/Hide
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C23H33F2N5O2
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1
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| 1 |
EC50 = 240 nM
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CP0504125
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(2S)-N-[(1S)-1-cyclohexyl-2-[[(3S)-1-[2-(3-fluorophenyl)ethyl]piperidin-3-yl]amino]-2-oxoethyl]-2-(methylamino)propanamide
Show/Hide
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C25H39FN4O2
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1
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| 1 |
EC50 = 279 nM
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CP0504123
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(2S)-3,3-dimethyl-2-[[(2S)-2-(methylamino)propanoyl]amino]-N-[(3S)-1-[2-[4-(trifluoromethyl)phenyl]ethyl]piperidin-3-yl]butanamide
Show/Hide
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C24H37F3N4O2
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1
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| 1 |
EC50 = 300 nM
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CP0492370
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(2S)-3,3-dimethyl-2-[[(2S)-2-(methylamino)propanoyl]amino]-N-[(3S)-1-(2-pyridin-4-ylethyl)piperidin-3-yl]butanamide
Show/Hide
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C22H37N5O2
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1
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| 1 |
EC50 > 370 nM
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CP0496385
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(2S)-3,3-dimethyl-2-[[(2S)-2-(methylamino)propanoyl]amino]-N-[(3S)-1-(2-pyridin-2-ylethyl)piperidin-3-yl]butanamide
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C22H37N5O2
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1
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| 1 |
EC50 > 370 nM
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CP0180985
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(2S)-1-[(2S)-3,3-dimethyl-2-[[(2S)-2-(methylamino)propanoyl]amino]butanoyl]-N-[(1R,2R)-2-prop-2-ynoxy-1,2,3,4-tetrahydronaphthalen-1-yl]pyrrolidine-2-carboxamide
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C28H40N4O4
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1
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| 1 |
EC50 > 370 nM
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CP0381600
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(2S)-1-[(2S)-2-[1-(2-hydroxyethyl)piperidin-4-yl]-2-[[(2S)-2-(methylamino)propanoyl]amino]acetyl]-N-[(1S,2R)-2-[6-[[(1S,2R)-1-[[(2S)-1-[(2S)-2-[1-(2-hydroxyethyl)piperidin-4-yl]-2-[[(2S)-2-(methylamino)propanoyl]amino]acetyl]pyrrolidine-2-carbonyl]amino]-2,3-dihydro-1H-inden-2-yl]oxy]hexa-2,4-diynoxy]-2,3-dihydro-1H-inden-1-yl]pyrrolidine-2-carboxamide
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C60H84N10O10
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1
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| 1 |
EC50 > 370 nM
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CP0387347
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(2S)-1-[(2S)-2-[[(2S)-2-(methylamino)propanoyl]amino]-2-piperidin-4-ylacetyl]-N-[(1S,2R)-2-[6-[[(1S,2R)-1-[[(2S)-1-[(2S)-2-[[(2S)-2-(methylamino)propanoyl]amino]-2-piperidin-4-ylacetyl]pyrrolidine-2-carbonyl]amino]-2,3-dihydro-1H-inden-2-yl]oxy]hexa-2,4-diynoxy]-2,3-dihydro-1H-inden-1-yl]pyrrolidine-2-carboxamide
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C56H76N10O8
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1
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| 1 |
EC50 > 370 nM
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CP0452563
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(2S)-1-[(2S)-2-(1-acetylpiperidin-4-yl)-2-[[(2S)-2-(methylamino)propanoyl]amino]acetyl]-N-[(1S,2R)-2-[6-[[(1S,2R)-1-[[(2S)-1-[(2S)-2-(1-acetylpiperidin-4-yl)-2-[[(2S)-2-(methylamino)propanoyl]amino]acetyl]pyrrolidine-2-carbonyl]amino]-2,3-dihydro-1H-inden-2-yl]oxy]hexa-2,4-diynoxy]-2,3-dihydro-1H-inden-1-yl]pyrrolidine-2-carboxamide
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C60H80N10O10
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1
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| 1 |
EC50 > 370 nM
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CP0458410
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(2S)-1-[(2S)-6-amino-2-[[(2S)-2-(methylamino)propanoyl]amino]hexanoyl]-N-[(1S,2R)-2-[6-[[(1S,2R)-1-[[(2S)-1-[(2S)-6-amino-2-[[(2S)-2-(methylamino)propanoyl]amino]hexanoyl]pyrrolidine-2-carbonyl]amino]-2,3-dihydro-1H-inden-2-yl]oxy]hexa-2,4-diynoxy]-2,3-dihydro-1H-inden-1-yl]pyrrolidine-2-carboxamide
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C54H76N10O8
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1
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| 1 |
EC50 > 370 nM
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CP0475597
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2-[(2R,5R)-2-[[(3R,5R)-3,5-dimethylmorpholin-4-yl]methyl]-5-methylpiperazin-1-yl]-1-[6-[(4-fluorophenyl)methyl]-5-(hydroxymethyl)-3,3-dimethyl-2H-pyrrolo[3,2-b]pyridin-1-yl]ethanone
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C31H44FN5O3
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1
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| 1 |
IC50 = 0.1 nM
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CP0386974
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1-[2-[(2R,5R)-2-[[(3R,5R)-3,5-dimethylmorpholin-4-yl]methyl]-5-methylpiperazin-1-yl]acetyl]-6-[(4-fluorophenyl)methyl]-3,3-dimethyl-2,4-dihydropyrrolo[3,2-b]pyridin-5-one
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C30H42FN5O3
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1
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| 1 |
IC50 = 0.13 nM
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CP0427159
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2-[[(2R,5R)-1-[2-[3-[(2,4-difluorophenyl)methyl]-7,7-dimethyl-6H-pyrrolo[3,2-c]pyridazin-5-yl]-2-oxoethyl]-5-methylpiperazin-2-yl]methyl]-4-fluoro-3H-isoindol-1-one
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C31H33F3N6O2
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1
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| 1 |
IC50 = 0.17 nM
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CP0386973
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1-[2-[(2R,5R)-2-[[(3R,5R)-3,5-dimethylmorpholin-4-yl]methyl]-5-methylpiperazin-1-yl]acetyl]-6-[(4-fluorophenyl)methyl]-3,3,4-trimethyl-2H-pyrrolo[3,2-b]pyridin-5-one
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C31H44FN5O3
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1
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| 1 |
IC50 = 0.18 nM
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CP0486045
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2-[(2R,5R)-2-[[(3R,5R)-3,5-dimethylmorpholin-4-yl]methyl]-5-methylpiperazin-1-yl]-1-[6-[(4-fluorophenyl)methyl]-3,3-dimethyl-2H-pyrrolo[3,2-b]pyridin-1-yl]ethanone
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C30H42FN5O2
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1
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| 1 |
IC50 = 0.19 nM
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CP0521075
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2-[[(2R,5R)-1-[2-[3-[(2,4-difluorophenyl)methyl]-7,7-dimethyl-6H-pyrrolo[3,2-c]pyridazin-5-yl]-2-oxoethyl]-5-methylpiperazin-2-yl]methyl]-5-fluoro-3H-isoindol-1-one
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C31H33F3N6O2
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1
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| 1 |
IC50 = 0.2 nM
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CP0356374
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1-[6-[(4-fluorophenyl)methyl]-5-(hydroxymethyl)-3,3-dimethyl-2H-pyrrolo[3,2-b]pyridin-1-yl]-2-[(2R,5R)-5-methyl-2-[[(3R)-3-methylmorpholin-4-yl]methyl]piperazin-1-yl]ethanone
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C30H42FN5O3
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1
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| 1 |
IC50 = 0.22 nM
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CP0486044
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2-[[(2R,5R)-1-[2-[3-[(2,4-difluorophenyl)methyl]-7,7-dimethyl-6H-pyrrolo[3,2-c]pyridazin-5-yl]-2-oxoethyl]-5-methylpiperazin-2-yl]methyl]-3H-isoindol-1-one
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C31H34F2N6O2
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1
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| 1 |
IC50 = 0.34 nM
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CP0408548
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2-[(2R,5R)-2-[[(3R,5R)-3,5-dimethylmorpholin-4-yl]methyl]-5-methylpiperazin-1-yl]-1-[6-[(4-fluoro-2-hydroxyphenyl)methyl]-3,3-dimethyl-2H-pyrrolo[3,2-b]pyridin-1-yl]ethanone
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C30H42FN5O3
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1
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| 1 |
IC50 = 0.59 nM
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CP0440745
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2-[(2R,5R)-2-[[(3R,5S)-3,5-dimethylmorpholin-4-yl]methyl]-5-methylpiperazin-1-yl]-1-[6-[(4-fluorophenyl)methyl]-3,3-dimethyl-2H-pyrrolo[3,2-b]pyridin-1-yl]ethanone
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C30H42FN5O2
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1
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| 1 |
IC50 = 0.62 nM
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CP0475596
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1-[2-[(2R,5R)-2-[[(3R,5R)-3,5-dimethylmorpholin-4-yl]methyl]-5-methylpiperazin-1-yl]acetyl]-6-[(4-fluorophenyl)methyl]-3,3-dimethyl-2H-pyrrolo[2,3-c]pyridin-5-one
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C30H42FN5O3
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1
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| 1 |
IC50 = 0.7 nM
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CP0475600
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2-[[(2R,5R)-1-[2-[3-[(2,4-difluorophenyl)methyl]-7,7-dimethyl-6H-pyrrolo[3,2-c]pyridazin-5-yl]-2-oxoethyl]-5-methylpiperazin-2-yl]methyl]-6-fluoro-3H-isoindol-1-one
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C31H33F3N6O2
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1
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| 1 |
IC50 = 0.74 nM
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CP0486043
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2-[[(2R,5R)-1-[2-[3-[(2,4-difluorophenyl)methyl]-7,7-dimethyl-6H-pyrrolo[3,2-c]pyridazin-5-yl]-2-oxoethyl]-5-methylpiperazin-2-yl]methyl]-1-oxo-3H-isoindole-5-carbonitrile
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C32H33F2N7O2
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1
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| 1 |
IC50 = 1 nM
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CP0427160
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2-[[(2R,5R)-1-[2-[6-[(4-fluorophenyl)methyl]-3,3-dimethyl-2H-pyrrolo[3,2-b]pyridin-1-yl]-2-oxoethyl]-5-methylpiperazin-2-yl]methyl]-3H-isoindol-1-one
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C32H36FN5O2
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1
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| 1 |
IC50 = 1.3 nM
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CP0475599
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2-[[(2R,5R)-1-[2-[3-[(2,4-difluorophenyl)methyl]-7,7-dimethyl-6H-pyrrolo[3,2-c]pyridazin-5-yl]-2-oxoethyl]-5-methylpiperazin-2-yl]methyl]-3-oxo-1H-isoindole-5-carbonitrile
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C32H33F2N7O2
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1
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| 1 |
IC50 = 1.6 nM
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CP0440720
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2-[(2R,5R)-2-[[(3R,5R)-3,5-dimethylmorpholin-4-yl]methyl]-5-methylpiperazin-1-yl]-1-[6-[(R)-(4-fluorophenyl)-hydroxymethyl]-3,3-dimethyl-2H-pyrrolo[3,2-b]pyridin-1-yl]ethanone
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C30H42FN5O3
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1
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| 1 |
IC50 = 2.3 nM
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CP0386979
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2-[[(2R,5R)-1-[2-[3-[(4-fluorophenyl)methyl]-7,7-dimethyl-6H-pyrrolo[3,2-c]pyridazin-5-yl]-2-oxoethyl]-5-methylpiperazin-2-yl]methyl]-3H-isoindol-1-one
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C31H35FN6O2
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1
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| 1 |
IC50 = 2.5 nM
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CP0386977
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2-[(2R,5R)-2-[[(3R,5R)-3,5-dimethylmorpholin-4-yl]methyl]-5-methylpiperazin-1-yl]-1-[6-[(S)-(4-fluorophenyl)-hydroxymethyl]-3,3-dimethyl-2H-pyrrolo[3,2-b]pyridin-1-yl]ethanone
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C30H42FN5O3
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1
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| 1 |
IC50 = 3.5 nM
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CP0482583
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1-[[(2R,5R)-1-[2-[6-[(4-fluorophenyl)methyl]-3,3-dimethyl-2H-pyrrolo[3,2-b]pyridin-1-yl]-2-oxoethyl]-5-methylpiperazin-2-yl]methyl]-3,4-dimethyl-2H-pyrrol-5-one
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C30H38FN5O2
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1
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| 1 |
IC50 = 3.8 nM
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CP0408551
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2-[(2R,5R)-2-[[(2R,5R)-2,5-dimethylmorpholin-4-yl]methyl]-5-methylpiperazin-1-yl]-1-[6-[(4-fluorophenyl)methyl]-3,3-dimethyl-2H-pyrrolo[3,2-b]pyridin-1-yl]ethanone
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C30H42FN5O2
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1
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| 1 |
IC50 = 4.2 nM
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CP0386980
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(6R)-4-[[(2R,5R)-1-[2-[6-[(4-fluorophenyl)methyl]-3,3-dimethyl-2H-pyrrolo[3,2-b]pyridin-1-yl]-2-oxoethyl]-5-methylpiperazin-2-yl]methyl]-6-methylmorpholin-3-one
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C29H38FN5O3
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1
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| 1 |
IC50 = 6.5 nM
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