Brief Information of the Cell Line and Protein
Cell Line ID: CL000111 , MDA-MB-231
Synonyms
MDA_MB_231
MDA-MB 231
MDA.MB.231
MDA MB 231
MDA MB231
MDA Mb231
MDA-MB231
MDAMB-231
MDAMB231
MDA-231
MDA-231P
MDA231
MDA231-BRE
MB231
MD Anderson-Metastatic Breast-231
Category Cancer cell line
Organism
Homo sapiens (Human)
Cellosaurus ID
CVCL_0062
Protein ID: PT00818 , Calcium/calmodulin-dependent protein kinase type 1D
Gene Name CAMK1D
Organism Homo sapiens, Human
Protein Classification Kinase
Uniprot ID Q8IU85
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000111  Protein ID: PT00818
 
Compound ID Compound Name Compound Formula
CP0096460
2-[(3S)-3-aminopiperidin-1-yl]-4-[3,5-bis(2-cyanopropan-2-yl)anilino]pyrimidine-5-carboxamide
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C24H30N8O
 1
1
IC50 = 8 nM
   TI
   LI
   LO
   TS
CP0096472
2-[(3S)-3-aminopiperidin-1-yl]-4-[[2,6-di(propan-2-yl)pyridin-4-yl]amino]pyrimidine-5-carboxamide
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C21H31N7O
 1
1
IC50 = 11 nM
   TI
   LI
   LO
   TS
CP0096476
2-[(3S)-3-aminopiperidin-1-yl]-4-[3-(2-cyanopropan-2-yl)-5-phenylanilino]pyrimidine-5-carboxamide
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C26H29N7O
 1
1
IC50 = 19 nM
   TI
   LI
   LO
   TS
CP0121514
2-[(3S)-3-aminopiperidin-1-yl]-4-(3-tert-butyl-5-methylsulfonylanilino)pyrimidine-5-carboxamide
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C21H30N6O3S
 1
1
IC50 = 28 nM
   TI
   LI
   LO
   TS
CP0352448
2-[(3S)-3-aminopiperidin-1-yl]-4-[3,5-di(propan-2-yl)anilino]pyrimidine-5-carboxamide
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C22H32N6O
 1
1
IC50 = 285 nM
   TI
   LI
   LO
   TS