Brief Information of the Cell Line and Protein
Cell Line ID: CL000108 , CCRF-CEM
 Cell Line Info 
Synonyms
CCRF/CEM
CCRFCEM
CCRF.CEM
CCRF CEM
CCRF
CEM
CEM-CCRF
CEM-CCRF (CAMR)
CCRF/CEM/0
CEM/0
CEM-0
CCRF-CEM/S
GM03671
GM03671C
Category Cancer cell line
Organism
Homo sapiens (Human)
Cellosaurus ID
CVCL_0207
Protein ID: PT00004 , Pol polyprotein
 Protein Info 
Gene Name POL
Organism Human immunodeficiency virus 1
Protein Classification Enzyme
Uniprot ID Q72874
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000108
 Cell Line Info 
 Protein ID: PT00004
 Protein Info 
 
Compound ID Compound Name Compound Formula
CP0122475
 Compound Info 
methyl (2S)-3-methyl-2-[[(2S,3S)-3-methyl-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[(2-methylpropan-2-yl)oxycarbonylamino]propanoyl]amino]propanoyl]amino]-3-phenylpropanoyl]-prop-2-enylamino]propanoyl]amino]pentanoyl]amino]butanoate
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C38H60N6O9
  1
1
IC50 = 3892.983233 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0296159
 Compound Info 
methyl (2S)-3-methyl-2-[[(2S,3S)-3-methyl-2-[[(2S)-2-[[(2S)-2-[(2-methylpropan-2-yl)oxycarbonylamino]-3-phenylpropanoyl]-prop-2-enylamino]propanoyl]amino]pentanoyl]amino]butanoate
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C32H50N4O7
  1
1
IC50 > 16590.07582 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0182290
 Compound Info 
methyl (2S)-2-[[(2S,3S)-2-[[2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-3-hydroxy-2-[(2-methylpropan-2-yl)oxycarbonylamino]propanoyl]amino]propanoyl]amino]propanoyl]amino]-3-phenylpropanoyl]-prop-2-enylamino]acetyl]amino]-3-methylpentanoyl]amino]-3-methylbutanoate
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C40H63N7O11
  1
1
IC50 > 24450.47556 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0217312
 Compound Info 
methyl (2S)-2-[[(2S,3S)-2-[[2-[2,3-dichloropropyl-[(2S)-2-[(2-methylpropan-2-yl)oxycarbonylamino]-3-phenylpropanoyl]amino]acetyl]amino]-3-methylpentanoyl]amino]-3-methylbutanoate
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C31H48Cl2N4O7
  1
1
IC50 > 50481.31585 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0046266
 Compound Info 
methyl (2S)-3-methyl-2-[[(2S,3S)-3-methyl-2-[[2-[[(2S)-2-[[(2S)-2-[(2-methylpropan-2-yl)oxycarbonylamino]propanoyl]amino]-3-phenylpropanoyl]-prop-2-enylamino]acetyl]amino]pentanoyl]amino]butanoate
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C34H53N5O8
  1
1
IC50 = 54104.84519 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0105952
 Compound Info 
methyl (2S)-2-[[(2S,3S)-2-[[2-[2,3-dibromopropyl-[(2S)-2-[(2-methylpropan-2-yl)oxycarbonylamino]-3-phenylpropanoyl]amino]acetyl]amino]-3-methylpentanoyl]amino]-3-methylbutanoate
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C31H48Br2N4O7
  1
1
IC50 = 56789.7936 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS