Brief Information of the Cell Line and Protein
Cell Line ID: CL000077 , Ba/F3
Synonyms
BA/F3
BaF3
BAF3
Baf3
Category Factor-dependent cell line
Organism
Mus musculus (Mouse)
Cellosaurus ID
CVCL_0161
Protein ID: PT06733 , Proto-oncogene tyrosine-protein kinase receptor Ret
Gene Name RET
Organism Mus musculus, Mouse
Protein Classification Kinase
Uniprot ID P35546
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000077  Protein ID: PT06733
 
Compound ID Compound Name Compound Formula
CP0346926
5-[(Z)-[6-[3-[[3-(4-methylpiperazin-1-yl)-5-(trifluoromethyl)benzoyl]amino]anilino]-2-oxo-1H-indol-3-ylidene]methyl]-1H-pyrrole-3-carboxylic acid
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C33H29F3N6O4
 1
1
IC50 = 100 nM
   TI
   LI
   LO
   TS
CP0111985
3-(4-methylimidazol-1-yl)-N-[3-[[(3Z)-2-oxo-3-(1H-pyrrol-2-ylmethylidene)-1H-indol-6-yl]amino]phenyl]-5-(trifluoromethyl)benzamide
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C31H23F3N6O2
 1
1
IC50 = 180 nM
   TI
   LI
   LO
   TS
CP0236690
3-(4-methylpiperazin-1-yl)-N-[3-[[(3Z)-2-oxo-3-(1H-pyrrol-2-ylmethylidene)-1H-indol-6-yl]amino]phenyl]-5-(trifluoromethyl)benzamide
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C32H29F3N6O2
 1
1
IC50 = 800 nM
   TI
   LI
   LO
   TS
CP0155468
1-[3-[[(3Z)-2-oxo-3-(1H-pyrrol-2-ylmethylidene)-1H-indol-6-yl]amino]phenyl]-3-[3-(trifluoromethyl)phenyl]urea
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C27H20F3N5O2
 1
1
IC50 = 1000 nM
   TI
   LI
   LO
   TS
CP0378059
N-[3-[[(3Z)-2-oxo-3-(1H-pyrrol-2-ylmethylidene)-1H-indol-6-yl]amino]phenyl]-3-(trifluoromethyl)benzamide
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C27H19F3N4O2
 1
1
IC50 = 1100 nM
   TI
   LI
   LO
   TS
CP0333107
1-[2-fluoro-5-(trifluoromethyl)phenyl]-3-[4-methyl-3-[[(3Z)-2-oxo-3-(1H-pyrrol-2-ylmethylidene)-1H-indol-6-yl]amino]phenyl]urea
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C28H21F4N5O2
 1
1
IC50 = 5300 nM
   TI
   LI
   LO
   TS