Brief Information of the Cell Line and Protein
Cell Line ID: CL000077 , Ba/F3
 Cell Line Info 
Synonyms
BA/F3
BaF3
BAF3
Baf3
Category Factor-dependent cell line
Organism
Mus musculus (Mouse)
Cellosaurus ID
CVCL_0161
Protein ID: PT06680 , Proto-oncogene tyrosine-protein kinase ROS
 Protein Info 
Gene Name ROS1
Organism Mus musculus, Mouse
Protein Classification Kinase
Uniprot ID Q78DX7
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000077
 Cell Line Info 
 Protein ID: PT06680
 Protein Info 
 
Compound ID Compound Name Compound Formula
CP0155468
 Compound Info 
1-[3-[[(3Z)-2-oxo-3-(1H-pyrrol-2-ylmethylidene)-1H-indol-6-yl]amino]phenyl]-3-[3-(trifluoromethyl)phenyl]urea
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C27H20F3N5O2
  1
1
IC50 = 1800 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0378059
 Compound Info 
N-[3-[[(3Z)-2-oxo-3-(1H-pyrrol-2-ylmethylidene)-1H-indol-6-yl]amino]phenyl]-3-(trifluoromethyl)benzamide
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C27H19F3N4O2
  1
1
IC50 = 5500 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0111985
 Compound Info 
3-(4-methylimidazol-1-yl)-N-[3-[[(3Z)-2-oxo-3-(1H-pyrrol-2-ylmethylidene)-1H-indol-6-yl]amino]phenyl]-5-(trifluoromethyl)benzamide
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C31H23F3N6O2
  1
1
IC50 = 5700 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0236690
 Compound Info 
3-(4-methylpiperazin-1-yl)-N-[3-[[(3Z)-2-oxo-3-(1H-pyrrol-2-ylmethylidene)-1H-indol-6-yl]amino]phenyl]-5-(trifluoromethyl)benzamide
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C32H29F3N6O2
  1
1
IC50 = 6000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0333107
 Compound Info 
1-[2-fluoro-5-(trifluoromethyl)phenyl]-3-[4-methyl-3-[[(3Z)-2-oxo-3-(1H-pyrrol-2-ylmethylidene)-1H-indol-6-yl]amino]phenyl]urea
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C28H21F4N5O2
  1
1
IC50 = 6000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0346926
 Compound Info 
5-[(Z)-[6-[3-[[3-(4-methylpiperazin-1-yl)-5-(trifluoromethyl)benzoyl]amino]anilino]-2-oxo-1H-indol-3-ylidene]methyl]-1H-pyrrole-3-carboxylic acid
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C33H29F3N6O4
  1
1
IC50 = 7000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS