Brief Information of the Cell Line and Protein
Cell Line ID: CL000077 , Ba/F3
Synonyms
BA/F3
BaF3
BAF3
Baf3
Category Factor-dependent cell line
Organism
Mus musculus (Mouse)
Cellosaurus ID
CVCL_0161
Protein ID: PT04740 , Hepatocyte growth factor receptor
Gene Name MET
Organism Mus musculus, Mouse
Protein Classification Kinase
Uniprot ID P16056
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000077  Protein ID: PT04740
 
Compound ID Compound Name Compound Formula
CP0155468
1-[3-[[(3Z)-2-oxo-3-(1H-pyrrol-2-ylmethylidene)-1H-indol-6-yl]amino]phenyl]-3-[3-(trifluoromethyl)phenyl]urea
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C27H20F3N5O2
 1
1
IC50 = 1500 nM
   TI
   LI
   LO
   TS
CP0236690
3-(4-methylpiperazin-1-yl)-N-[3-[[(3Z)-2-oxo-3-(1H-pyrrol-2-ylmethylidene)-1H-indol-6-yl]amino]phenyl]-5-(trifluoromethyl)benzamide
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C32H29F3N6O2
 1
1
IC50 = 5100 nM
   TI
   LI
   LO
   TS
CP0333107
1-[2-fluoro-5-(trifluoromethyl)phenyl]-3-[4-methyl-3-[[(3Z)-2-oxo-3-(1H-pyrrol-2-ylmethylidene)-1H-indol-6-yl]amino]phenyl]urea
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C28H21F4N5O2
 1
1
IC50 = 5800 nM
   TI
   LI
   LO
   TS
CP0378059
N-[3-[[(3Z)-2-oxo-3-(1H-pyrrol-2-ylmethylidene)-1H-indol-6-yl]amino]phenyl]-3-(trifluoromethyl)benzamide
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C27H19F3N4O2
 1
1
IC50 = 9600 nM
   TI
   LI
   LO
   TS
CP0111985
3-(4-methylimidazol-1-yl)-N-[3-[[(3Z)-2-oxo-3-(1H-pyrrol-2-ylmethylidene)-1H-indol-6-yl]amino]phenyl]-5-(trifluoromethyl)benzamide
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C31H23F3N6O2
 1
1
IC50 > 10000 nM
   TI
   LI
   LO
   TS