Compound ID |
Compound Name |
Compound Formula |
CP0508321
|
7-[[(1R,2S)-2-aminocyclohexyl]amino]-5-(3-methylanilino)-4-oxo-3H-pyrido[3,4-d]pyridazine-8-carbonitrile
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|
C21H23N7O
|
1
|
1 |
GI50 = 1.9 nM
|
|
|
CP0427066
|
7-[[(1R,2S)-2-aminocyclohexyl]amino]-5-(3-methylanilino)-3H-pyrido[3,4-d]pyridazin-4-one
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|
C20H24N6O
|
1
|
1 |
GI50 = 69 nM
|
|
|
CP0482287
|
7-[(2-aminocyclohexyl)amino]-5-(3-methylanilino)-3H-pyrido[3,4-d]pyridazin-4-one
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|
C20H24N6O
|
1
|
1 |
GI50 = 83 nM
|
|
|
CP0458204
|
7-[(2-aminocyclohexyl)amino]-8-chloro-5-(3-methylanilino)-3H-pyrido[3,4-d]pyridazin-4-one
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|
C20H23ClN6O
|
1
|
1 |
GI50 = 120 nM
|
|
|
CP0420693
|
7-[[(1R,2S)-2-aminocyclohexyl]amino]-8-bromo-5-(3-methylanilino)-3H-pyrido[3,4-d]pyridazin-4-one
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|
C20H23BrN6O
|
1
|
1 |
GI50 = 140 nM
|
|
|
CP0534495
|
6-[(2-aminocyclohexyl)amino]-8-(3-methylanilino)-2H-2,7-naphthyridin-1-one
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|
C21H25N5O
|
1
|
1 |
GI50 = 460 nM
|
|
|
CP0531980
|
6-[(2-aminocyclohexyl)amino]-8-(3-methylanilino)-3,4-dihydro-2H-2,7-naphthyridin-1-one
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|
C21H27N5O
|
1
|
1 |
GI50 = 480 nM
|
|
|
CP0427064
|
3-amino-6-[(2-aminocyclohexyl)amino]-1-benzylpyrrolo[2,3-b]pyridine-5-carbonitrile
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|
C21H24N6
|
1
|
1 |
GI50 > 4000 nM
|
|
|