Brief Information of the Cell Line and Protein
Cell Line ID: CL000077 , Ba/F3
 Cell Line Info 
Synonyms
BA/F3
BaF3
BAF3
Baf3
Category Factor-dependent cell line
Organism
Mus musculus (Mouse)
Cellosaurus ID
CVCL_0161
Protein ID: PT01661 , Tyrosine-protein kinase receptor TYRO3
 Protein Info 
Gene Name TYRO3
Organism Homo sapiens, Human
Protein Classification Kinase
Uniprot ID Q06418
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000077
 Cell Line Info 
 Protein ID: PT01661
 Protein Info 
 
Compound ID Compound Name Compound Formula
CP0418567
 Compound Info 
3-[4-amino-7-[3-(hydroxymethyl)cyclobutyl]pyrrolo[2,3-d]pyrimidin-5-yl]phenol
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C17H18N4O2
  1
1
IC50 = 2200 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0061016
 Compound Info 
3-(4-Amino-7-cyclopentyl-7H-pyrrolo[2,3-d]pyrimidin-5-yl)-phenol
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C17H18N4O
  1
1
IC50 = 3100 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0388620
 Compound Info 
methyl N-[4-[7-amino-3-(3,4-dimethoxyphenyl)-5-(1-methylpiperidin-4-yl)oxypyrazolo[1,5-a]pyrimidin-6-yl]phenyl]carbamate
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C28H32N6O5
  1
1
IC50 = 3700 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0385511
 Compound Info 
1-[4-[6-[(2R)-2-(3-fluorophenyl)pyrrolidin-1-yl]imidazo[1,2-b]pyridazin-3-yl]pyridin-2-yl]piperidin-4-ol
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C26H27FN6O
  1
1
IC50 = 5000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0385508
 Compound Info 
2-[4-[4-[6-[(2R)-2-(3-fluorophenyl)pyrrolidin-1-yl]imidazo[1,2-b]pyridazin-3-yl]pyridin-2-yl]piperazin-1-yl]acetic acid
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C27H28FN7O2
  1
1
IC50 = 5200 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0388615
 Compound Info 
3-(3,4-dimethoxyphenyl)-5-(1-methylpiperidin-4-yl)oxy-6-(1,3-thiazol-2-yl)pyrazolo[1,5-a]pyrimidin-7-amine
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C23H26N6O3S
  1
1
IC50 > 11000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0388616
 Compound Info 
3-(3,4-dimethoxyphenyl)-5-(1-methylpiperidin-4-yl)oxy-6-phenylpyrazolo[1,5-a]pyrimidin-7-amine
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C26H29N5O3
  1
1
IC50 > 11000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0138866
 Compound Info 
1-[4-[3-[4-amino-5-(2-fluoro-5-hydroxyphenyl)pyrrolo[2,3-d]pyrimidin-7-yl]cyclobutyl]piperazin-1-yl]ethanone
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C22H25FN6O2
  1
1
IC50 > 11000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS