| Compound ID |
Compound Name |
Compound Formula |
|
CP0317631
|
N-[2,5-difluoro-4-[2-[[4-(4-methylpiperazin-1-yl)piperidine-1-carbonyl]amino]pyridin-4-yl]oxyphenyl]-3-(4-fluorophenyl)-2,4-dioxo-1-propan-2-ylpyrimidine-5-carboxamide
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|
C36H39F3N8O5
|
1
|
| 1 |
IC50 = 1.9 nM
|
|
|
|
CP0563520
|
1-cyclopentyl-N-[3-fluoro-4-[2-[[2-(1-methylpiperidin-4-yl)acetyl]amino]pyridin-4-yl]oxyphenyl]-3-(4-fluorophenyl)-2,4-dioxopyrimidine-5-carboxamide
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|
C35H36F2N6O5
|
1
|
| 1 |
IC50 = 2.8 nM
|
|
|
|
CP0564219
|
3-(4-fluorophenyl)-N-[4-[2-[[2-(1-methylpiperidin-4-yl)acetyl]amino]pyridin-4-yl]oxyphenyl]-2,4-dioxo-1-propan-2-ylpyrimidine-5-carboxamide
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|
C33H35FN6O5
|
1
|
| 1 |
IC50 = 5.9 nM
|
|
|
|
CP0553501
|
1-cyclopentyl-3-(4-fluorophenyl)-N-[4-[6-[[4-(4-methylpiperazin-1-yl)piperidine-1-carbonyl]amino]pyrimidin-4-yl]oxyphenyl]-2,4-dioxopyrimidine-5-carboxamide
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|
C37H42FN9O5
|
1
|
| 1 |
IC50 = 6.3 nM
|
|
|
|
CP0557698
|
N-[2-fluoro-4-[2-[[2-(1-methylpiperidin-4-yl)acetyl]amino]pyridin-4-yl]oxyphenyl]-3-(4-fluorophenyl)-2,4-dioxo-1-propan-2-ylpyrimidine-5-carboxamide
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|
C33H34F2N6O5
|
1
|
| 1 |
IC50 = 7.6 nM
|
|
|
|
CP0557697
|
N-[4-[6-(cyclopropanecarbonylamino)pyrimidin-4-yl]oxyphenyl]-3-(4-fluorophenyl)-2,4-dioxo-1-propan-2-ylpyrimidine-5-carboxamide
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|
C28H25FN6O5
|
1
|
| 1 |
IC50 = 9 nM
|
|
|
|
CP0543363
|
N-[4-[6-(azetidine-1-carbonylamino)pyrimidin-4-yl]oxyphenyl]-3-(4-fluorophenyl)-2,4-dioxo-1-propan-2-ylpyrimidine-5-carboxamide
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|
C28H26FN7O5
|
1
|
| 1 |
IC50 = 11 nM
|
|
|
|
CP0553500
|
3-(4-fluorophenyl)-N-[4-[6-[[4-(4-methylpiperazin-1-yl)piperidine-1-carbonyl]amino]pyrimidin-4-yl]oxyphenyl]-2,4-dioxo-1-propan-2-ylpyrimidine-5-carboxamide
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|
C35H40FN9O5
|
1
|
| 1 |
IC50 = 15 nM
|
|
|
|
CP0554517
|
3-(4-fluorophenyl)-2,4-dioxo-1-propan-2-yl-N-[4-[6-(pyrrolidine-1-carbonylamino)pyrimidin-4-yl]oxyphenyl]pyrimidine-5-carboxamide
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|
C29H28FN7O5
|
1
|
| 1 |
IC50 = 15 nM
|
|
|
|
CP0553502
|
N-[2,5-difluoro-4-[2-[[4-(4-methylpiperazin-1-yl)piperidine-1-carbonyl]amino]pyridin-4-yl]oxyphenyl]-2,5-dioxo-1-phenyl-7,8-dihydro-6H-quinoline-3-carboxamide
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|
C38H39F2N7O5
|
1
|
| 1 |
IC50 = 16 nM
|
|
|
|
CP0563667
|
3-(4-fluorophenyl)-N-[4-[6-[(3-hydroxyazetidine-1-carbonyl)amino]pyrimidin-4-yl]oxyphenyl]-2,4-dioxo-1-propan-2-ylpyrimidine-5-carboxamide
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|
C28H26FN7O6
|
1
|
| 1 |
IC50 = 20 nM
|
|
|
|
CP0554516
|
1-cyclopropyl-N-[3-fluoro-4-[2-[[2-(1-methylpiperidin-4-yl)acetyl]amino]pyridin-4-yl]oxyphenyl]-3-(4-fluorophenyl)-2,4-dioxopyrimidine-5-carboxamide
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|
C33H32F2N6O5
|
1
|
| 1 |
IC50 = 23 nM
|
|
|
|
CP0317628
|
3-(4-fluorophenyl)-N-[4-[6-[[3-(methylamino)azetidine-1-carbonyl]amino]pyrimidin-4-yl]oxyphenyl]-2,4-dioxo-1-propan-2-ylpyrimidine-5-carboxamide
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|
C29H29FN8O5
|
1
|
| 1 |
IC50 = 40 nM
|
|
|
|
CP0317629
|
3-(4-fluorophenyl)-2,4-dioxo-1-propan-2-yl-N-[4-[6-[(3-pyrrolidin-1-ylazetidine-1-carbonyl)amino]pyrimidin-4-yl]oxyphenyl]pyrimidine-5-carboxamide
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|
C32H33FN8O5
|
1
|
| 1 |
IC50 = 49 nM
|
|
|
|
CP0566934
|
1-cyclopropyl-3-(4-fluorophenyl)-N-[4-[6-[[4-(4-methylpiperazin-1-yl)piperidine-1-carbonyl]amino]pyrimidin-4-yl]oxyphenyl]-2,4-dioxopyrimidine-5-carboxamide
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|
C35H38FN9O5
|
1
|
| 1 |
IC50 = 51 nM
|
|
|
|
CP0563666
|
N-[4-[2-[[2-(dimethylamino)acetyl]amino]pyridin-4-yl]oxyphenyl]-3-(4-fluorophenyl)-2,4-dioxo-1-propan-2-ylpyrimidine-5-carboxamide
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|
C29H29FN6O5
|
1
|
| 1 |
IC50 = 90 nM
|
|
|
|
CP0570986
|
3-(4-fluorophenyl)-1-methyl-N-[4-[6-[[4-(4-methylpiperazin-1-yl)piperidine-1-carbonyl]amino]pyrimidin-4-yl]oxyphenyl]-2,4-dioxopyrimidine-5-carboxamide
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|
C33H36FN9O5
|
1
|
| 1 |
IC50 = 173 nM
|
|
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