| Compound ID |
Compound Name |
Compound Formula |
|
CP0389516
|
N-[[4-[2-(2-aminopyridin-3-yl)-6-bromoimidazo[4,5-b]pyridin-3-yl]phenyl]methyl]benzamide
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|
C25H19BrN6O
|
3
|
| 1 |
IC50 < 12 nM
|
|
|
| 2 |
IC50 = 170 nM
|
|
|
| 3 |
IC50 = 3100 nM
|
|
|
|
CP0397465
|
2-[4-[5-(3-acetamidophenyl)-2-(2-aminopyridin-3-yl)imidazo[4,5-b]pyridin-3-yl]phenyl]-N-(3-fluorophenyl)acetamide
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|
C33H26FN7O2
|
3
|
| 1 |
IC50 = 15 nM
|
|
|
| 2 |
IC50 = 120 nM
|
|
|
| 3 |
IC50 = 140 nM
|
|
|
|
CP0376695
|
N-[[4-[5-(3-acetamidophenyl)-2-(2-aminopyridin-3-yl)imidazo[4,5-b]pyridin-3-yl]phenyl]methyl]-3-fluorobenzamide
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|
C33H26FN7O2
|
3
|
| 1 |
IC50 = 27 nM
|
|
|
| 2 |
IC50 = 32 nM
|
|
|
| 3 |
IC50 = 250 nM
|
|
|
|
CP0397469
|
N-[[4-[2-(2-aminopyridin-3-yl)-5-pyridin-3-ylimidazo[4,5-b]pyridin-3-yl]phenyl]methyl]benzamide
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|
C30H23N7O
|
3
|
| 1 |
IC50 = 34 nM
|
|
|
| 2 |
IC50 = 67 nM
|
|
|
| 3 |
IC50 = 740 nM
|
|
|
|
CP0420108
|
N-[3-[3-[4-(1-aminocyclobutyl)phenyl]-2-(2-aminopyridin-3-yl)imidazo[4,5-b]pyridin-5-yl]phenyl]acetamide;hydrochloride
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|
C29H28ClN7O
|
3
|
| 1 |
IC50 = 37 nM
|
|
|
| 2 |
IC50 = 41 nM
|
|
|
| 3 |
IC50 > 3000 nM
|
|
|
|
CP0389476
|
2-[4-[5-(3-acetamidophenyl)-2-(2-aminopyridin-3-yl)imidazo[4,5-b]pyridin-3-yl]phenyl]-N-phenylacetamide
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|
C33H27N7O2
|
3
|
| 1 |
IC50 = 46 nM
|
|
|
| 2 |
IC50 = 54 nM
|
|
|
| 3 |
IC50 = 310 nM
|
|
|
|
CP0405066
|
N-[[4-[2-(2-aminopyridin-3-yl)-6-pyridin-3-ylimidazo[4,5-b]pyridin-3-yl]phenyl]methyl]-3-fluorobenzamide
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|
C30H22FN7O
|
3
|
| 1 |
IC50 = 54 nM
|
|
|
| 2 |
IC50 = 200 nM
|
|
|
| 3 |
IC50 = 580 nM
|
|
|
|
CP0453697
|
2-[4-[2-(2-aminopyridin-3-yl)-5-pyridin-3-ylimidazo[4,5-b]pyridin-3-yl]phenyl]-N-phenylacetamide
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|
C30H23N7O
|
3
|
| 1 |
IC50 = 55 nM
|
|
|
| 2 |
IC50 = 65 nM
|
|
|
| 3 |
IC50 = 480 nM
|
|
|
|
CP0441192
|
N-[[4-[2-(2-aminopyridin-3-yl)-6-pyridin-3-ylimidazo[4,5-b]pyridin-3-yl]phenyl]methyl]benzamide
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|
C30H23N7O
|
3
|
| 1 |
IC50 = 62 nM
|
|
|
| 2 |
IC50 = 100 nM
|
|
|
| 3 |
IC50 = 950 nM
|
|
|
|
CP0389475
|
N-[[4-[2-(2-aminopyridin-3-yl)-5-phenylimidazo[4,5-b]pyridin-3-yl]phenyl]methyl]benzamide
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|
C31H24N6O
|
3
|
| 1 |
IC50 = 68 nM
|
|
|
| 2 |
IC50 = 180 nM
|
|
|
| 3 |
IC50 = 410 nM
|
|
|
|
CP0376692
|
N-[[4-[5-(3-acetamidophenyl)-2-(2-aminopyridin-3-yl)imidazo[4,5-b]pyridin-3-yl]phenyl]methyl]benzamide
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|
C33H27N7O2
|
3
|
| 1 |
IC50 = 130 nM
|
|
|
| 2 |
IC50 = 140 nM
|
|
|
| 3 |
IC50 = 910 nM
|
|
|
|
CP0376644
|
N-[[4-[2-(2-aminopyridin-3-yl)-5-pyridin-3-ylimidazo[4,5-b]pyridin-3-yl]phenyl]methyl]-3-fluorobenzamide
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|
C30H22FN7O
|
3
|
| 1 |
IC50 = 190 nM
|
|
|
| 2 |
IC50 = 690 nM
|
|
|
| 3 |
IC50 = 1300 nM
|
|
|
|
CP0397464
|
N-[[4-[2-(2-aminopyridin-3-yl)-6-cyclopentylimidazo[4,5-b]pyridin-3-yl]phenyl]methyl]benzamide
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|
C30H28N6O
|
3
|
| 1 |
IC50 = 210 nM
|
|
|
| 2 |
IC50 = 270 nM
|
|
|
| 3 |
IC50 = 2100 nM
|
|
|
|
CP0024409
|
2-[4-[2-(2-aminopyridin-3-yl)imidazo[4,5-b]pyridin-3-yl]phenyl]-N-phenylacetamide
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|
C25H20N6O
|
3
|
| 1 |
IC50 = 210 nM
|
|
|
| 2 |
IC50 = 1300 nM
|
|
|
| 3 |
IC50 > 10000 nM
|
|
|
|
CP0441194
|
N-[[4-[2-(2-aminopyridin-3-yl)-6-phenylimidazo[4,5-b]pyridin-3-yl]phenyl]methyl]benzamide
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|
C31H24N6O
|
3
|
| 1 |
IC50 = 330 nM
|
|
|
| 2 |
IC50 = 680 nM
|
|
|
| 3 |
IC50 = 1800 nM
|
|
|
|
CP0022681
|
N-[[4-[2-(2-aminopyridin-3-yl)imidazo[4,5-b]pyridin-3-yl]phenyl]methyl]benzamide
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|
C25H20N6O
|
3
|
| 1 |
IC50 = 370 nM
|
|
|
| 2 |
IC50 = 410 nM
|
|
|
| 3 |
IC50 > 10000 nM
|
|
|
