Brief Information of the Compound and Protein
Compound Name
 Compound Info 
N-[3-[3-[4-(1-aminocyclobutyl)phenyl]-2-(2-aminopyridin-3-yl)imidazo[4,5-b]pyridin-5-yl]phenyl]acetamide;hydrochloride
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 PubChem ID
CID: 67312397
Canonical SMILES
Cl.CC(=O)Nc1cccc(c1)-c1ccc2nc(-c3cccnc3N)n(-c3ccc(cc3)C3(N)CCC3)c2n1
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Compound Formula C29H28ClN7O
Compound Structure
Protein Name
 Protein Info 
RAC-alpha serine/threonine-protein kinase
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
AGC protein kinase group
>
AGC protein kinase AKT family
Uniprot ID
P31749
Gene Name
AKT1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000072 A2780
 Cell Line Info 
Homo sapiens (Human)  3
1
IC50 = 37 nM
   TI
   LI
   LO
   TS
2
IC50 = 41 nM
   TI
   LI
   LO
   TS
3
IC50 > 3000 nM
   TI
   LI
   LO
   TS
CL000013 Sf9
 Cell Line Info 
Spodoptera frugiperda (Fall armyworm)  2
1
IC50 = 2.3 nM
   TI
   LI
   LO
   TS
2
IC50 = 2.8 nM
   TI
   LI
   LO
   TS