Brief Information of the Cell Line and Protein
Cell Line ID: CL000065 , HEK293-EBNA
Synonyms
293 c18
293c18
HEK 293 c18
HEK-293 c18
HEK293-EBNA1
HEK-293-EBNA
HEK 293-EBNA
HEK 293 EBNA
HEK293EBNA
293 EBNA
293-EBNA1
293-EBNA
293/EBNA
293EBNA
EBNA-293
EBNA293
293E
HEK293E
HEK/EBNA
HEK-EBNA
HEK.EBNA
293/EBNA-1
Category Transformed cell line
Organism
Homo sapiens (Human)
Cellosaurus ID
CVCL_6974
Protein ID: PT01658 , Oxytocin receptor
Gene Name OXTR
Organism Homo sapiens, Human
Protein Classification Membrane receptor
Uniprot ID P30559
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000065  Protein ID: PT01658
 
Compound ID Compound Name Compound Formula
CP0049593
2-(4-chloro-N-[4-[2-(2-methoxyethoxy)ethoxy]phenyl]sulfonylanilino)-N-[(2-hydroxy-1H-indol-3-yl)imino]acetamide
   Show/Hide
C27H27ClN4O7S
 2
1
IC50 = 7 nM
   TI
   LI
   LO
   TS
2
Ki = 3 nM
   TI
   LI
   LO
   TS
CP0377968
CHEMBL2113185
   Show/Hide
C28H28ClN5O6S
 2
1
IC50 = 7 nM
   TI
   LI
   LO
   TS
2
Ki = 0.9 nM
   TI
   LI
   LO
   TS
CP0176028
CHEMBL2113211
   Show/Hide
C25H23ClN4O6S
 2
1
IC50 = 8 nM
   TI
   LI
   LO
   TS
2
Ki = 7 nM
   TI
   LI
   LO
   TS
CP0198143
CHEMBL2113201
   Show/Hide
C27H28ClN5O5S
 2
1
IC50 = 14 nM
   TI
   LI
   LO
   TS
2
Ki = 1.1 nM
   TI
   LI
   LO
   TS
CP0302223
(Z)-3-(4-(N-(4-chlorophenyl)-N-(2-oxo-2-(2-(2-oxoindolin-3-ylidene)hydrazinyl)ethyl)sulfamoyl)phenyl)-N-(3-(dimethylamino)propyl)propanamide
   Show/Hide
C30H33ClN6O5S
 2
1
IC50 = 14 nM
   TI
   LI
   LO
   TS
2
Ki = 0.65 nM
   TI
   LI
   LO
   TS
CP0485778
2-(4-chloro-N-[4-[3-(dimethylamino)propoxy]phenyl]sulfonylanilino)-N-[(1-hydroxy-3-oxo-2H-isoquinolin-4-yl)imino]acetamide
   Show/Hide
C28H28ClN5O6S
 2
1
IC50 = 15 nM
   TI
   LI
   LO
   TS
2
Ki = 1.6 nM
   TI
   LI
   LO
   TS
CP0070065
4-ethoxy-N-(2-oxo-2-(2-(2-oxoindolin-3-ylidene)hydrazinyl)ethyl)-N-p-tolylbenzenesulfonamide
   Show/Hide
C25H24N4O5S
 2
1
IC50 = 30 nM
   TI
   LI
   LO
   TS
2
Ki = 14 nM
   TI
   LI
   LO
   TS
CP0250764
2-(4-chloro-N-[4-(3-hydroxypropyl)phenyl]sulfonylanilino)-N-[(2-hydroxy-1H-indol-3-yl)imino]acetamide
   Show/Hide
C25H23ClN4O5S
 2
1
IC50 = 32 nM
   TI
   LI
   LO
   TS
2
Ki = 4.1 nM
   TI
   LI
   LO
   TS
CP0250765
CHEMBL2113177
   Show/Hide
C28H29ClN6O5S
 2
1
IC50 = 49 nM
   TI
   LI
   LO
   TS
2
Ki = 7 nM
   TI
   LI
   LO
   TS
CP0177122
(2S)-5-amino-2-{[(2S)-1-{[(4R,7S,10S,13S,16R)-13-[(2S)-butan-2-yl]-7-(carbamoylmethyl)-16-[(4-ethoxyphenyl)methyl]-10-[(1R)-1-hydroxyethyl]-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentaazacycloicosan-4-yl]carbonyl}pyrrolidin-2-yl]formamido}-N-(carbamoylmethyl)pentanamide
   Show/Hide
C43H67N11O12S2
 2
1
IC50 = 59 nM
   TI
   LI
   LO
   TS
2
Ki = 27 nM
   TI
   LI
   LO
   TS
CP0198144
2-(4-chloro-N-[4-[2-(dimethylamino)ethoxy]phenyl]sulfonylanilino)-N-[(2-hydroxy-1H-indol-3-yl)imino]acetamide
   Show/Hide
C26H26ClN5O5S
 2
1
IC50 = 59 nM
   TI
   LI
   LO
   TS
2
Ki = 2.1 nM
   TI
   LI
   LO
   TS
CP0446409
2-(4-chloro-N-[4-[3-(dimethylamino)propoxy]phenyl]sulfonylanilino)-N-[(2-hydroxy-1H-pyrrolo[3,2-c]pyridin-3-yl)imino]acetamide
   Show/Hide
C26H27ClN6O5S
 2
1
IC50 = 840 nM
   TI
   LI
   LO
   TS
2
Ki = 115 nM
   TI
   LI
   LO
   TS
CP0483645
3-[4-[(4-chlorophenyl)-[2-[(2-hydroxy-1H-indol-3-yl)diazenyl]-2-oxoethyl]sulfamoyl]phenyl]-N-(3-hydroxypropyl)propanamide
   Show/Hide
C28H28ClN5O6S
 1
1
Ki = 0.9 nM
   TI
   LI
   LO
   TS
CP0303775
CHEMBL2113198
   Show/Hide
C24H21ClN4O5S
 1
1
Ki = 3.9 nM
   TI
   LI
   LO
   TS
CP0292348
2-(4-fluoro-2-methylphenyl)-5-(4-(6-methoxypyridin-3-yl)-5-methyl-4H-1,2,4-triazol-3-yl)pyrazine
   Show/Hide
C20H17FN6O
 1
1
Ki = 6 nM
   TI
   LI
   LO
   TS
CP0439005
2-[N-(benzenesulfonyl)-4-chloroanilino]-N-[(2-hydroxy-1H-indol-3-yl)imino]acetamide
   Show/Hide
C22H17ClN4O4S
 1
1
Ki = 8.7 nM
   TI
   LI
   LO
   TS
CP0194007
5-(3-(3-(2-chloro-4-fluorophenoxy)azetidin-1-yl)-5-(methoxymethyl)-4H-1,2,4-triazol-4-yl)-2-methoxypyridine
   Show/Hide
C19H19ClFN5O3
 1
1
Ki = 9.5 nM
   TI
   LI
   LO
   TS
CP0480330
2-(4-chloro-N-(4-propoxyphenyl)sulfonylanilino)-N-[(2-hydroxy-1H-indol-3-yl)imino]acetamide
   Show/Hide
C25H23ClN4O5S
 1
1
Ki = 10 nM
   TI
   LI
   LO
   TS
CP0718296
N-(4-chlorophenyl)-4-ethoxy-N-(2-(2-(2-hydroxybenzylidene)hydrazinyl)-2-oxoethyl)benzenesulfonamide
   Show/Hide
C23H22ClN3O5S
 1
1
Ki = 15 nM
   TI
   LI
   LO
   TS
CP0198146
2-(N-(4-butoxyphenyl)sulfonyl-4-chloroanilino)-N-[(2-hydroxy-1H-indol-3-yl)imino]acetamide
   Show/Hide
C26H25ClN4O5S
 1
1
Ki = 18 nM
   TI
   LI
   LO
   TS
CP0889531
N-(4-chlorophenyl)-3,4-dimethoxy-N-{2-oxo-2-[(2E)-2-(2-oxo-1,2-dihydro-3H-indol-3-ylidene)hydrazino]ethyl}benzenesulfonamide
   Show/Hide
C24H21ClN4O6S
 1
1
Ki = 18 nM
   TI
   LI
   LO
   TS
CP0467144
CHEMBL2113215
   Show/Hide
C24H22N4O5S
 1
1
Ki = 20 nM
   TI
   LI
   LO
   TS
CP0515591
N-[(2-hydroxy-1H-indol-3-yl)imino]-2-(4-methyl-N-(4-propoxyphenyl)sulfonylanilino)acetamide
   Show/Hide
C26H26N4O5S
 1
1
Ki = 21 nM
   TI
   LI
   LO
   TS
CP0331982
5-(3-(4-ethoxy-3-methylphenyl)-5-(ethoxymethyl)-4H-1,2,4-triazol-4-yl)-2-methoxypyridine
   Show/Hide
C20H24N4O3
 1
1
Ki = 28 nM
   TI
   LI
   LO
   TS
CP0483731
2-(4-chloro-N-(4-propylphenyl)sulfonylanilino)-N-[(2-hydroxy-1H-indol-3-yl)imino]acetamide
   Show/Hide
C25H23ClN4O4S
 1
1
Ki = 36 nM
   TI
   LI
   LO
   TS
CP0910329
4-ethoxy-N-{2-oxo-2-[2-(2-oxo-1,2-dihydro-3H-indol-3-ylidene)hydrazino]ethyl}-N-phenylbenzenesulfonamide
   Show/Hide
C24H22N4O5S
 1
1
Ki = 36 nM
   TI
   LI
   LO
   TS
CP0464488
2-(4-chloro-N-thiophen-2-ylsulfonylanilino)-N-[(2-hydroxy-1H-indol-3-yl)imino]acetamide
   Show/Hide
C20H15ClN4O4S2
 1
1
Ki = 37 nM
   TI
   LI
   LO
   TS
CP0415346
(R)-(4-(methoxyimino)-2-(3-methyl-1,2,4-oxadiazol-5-yl)pyrrolidin-1-yl)(2'-methylbiphenyl-4-yl)methanone
   Show/Hide
C22H22N4O3
 1
1
Ki = 50 nM
   TI
   LI
   LO
   TS
CP0415340
2-methoxy-5-(3-(2'-methoxybiphenyl-4-yl)-5-methyl-4H-1,2,4-triazol-4-yl)pyridine
   Show/Hide
C22H20N4O2
 1
1
Ki = 56 nM
   TI
   LI
   LO
   TS
CP0910343
4-ethoxy-N-{2-[2-(2-hydroxybenzylidene)hydrazino]-2-oxoethyl}-N-(4-methylphenyl)benzenesulfonamide
   Show/Hide
C24H25N3O5S
 1
1
Ki = 60 nM
   TI
   LI
   LO
   TS
CP0453756
2-(N-(4-tert-butylphenyl)sulfonyl-4-chloroanilino)-N-[(2-hydroxy-1H-indol-3-yl)imino]acetamide
   Show/Hide
C26H25ClN4O4S
 1
1
Ki = 61 nM
   TI
   LI
   LO
   TS
CP0321565
2-(4-chloro-N-(4-ethoxyphenyl)sulfonylanilino)-N-[(2-hydroxy-1H-pyrrolo[3,2-c]pyridin-3-yl)imino]acetamide
   Show/Hide
C23H20ClN5O5S
 1
1
Ki = 64 nM
   TI
   LI
   LO
   TS
CP0341519
2-[N-(benzenesulfonyl)-4-methylanilino]-N-[(E)-(2-hydroxyphenyl)methylideneamino]acetamide
   Show/Hide
C22H21N3O4S
 1
1
Ki = 67 nM
   TI
   LI
   LO
   TS
CP0377965
2-[N-(benzenesulfonyl)-4-chloroanilino]-N-[(E)-(2-hydroxyphenyl)methylideneamino]acetamide
   Show/Hide
C21H18ClN3O4S
 1
1
Ki = 67 nM
   TI
   LI
   LO
   TS
CP0393452
2-[N-(benzenesulfonyl)anilino]-N-[(2-hydroxy-1H-indol-3-yl)imino]acetamide
   Show/Hide
C22H18N4O4S
 1
1
Ki = 90 nM
   TI
   LI
   LO
   TS
CP0441895
2-[N-(benzenesulfonyl)-4-methylanilino]-N-(3-chloro-2-methylphenyl)acetamide
   Show/Hide
C22H21ClN2O3S
 1
1
Ki = 93 nM
   TI
   LI
   LO
   TS
CP0107768
2-[Benzenesulfonyl-(4-methoxy-phenyl)-amino]-N-(3-chloro-2-methyl-phenyl)-acetamide
   Show/Hide
C22H21ClN2O4S
 1
1
Ki = 100 nM
   TI
   LI
   LO
   TS
CP0907489
N-(4-methylphenyl)-N-{2-oxo-2-[2-(2-oxo-1,2-dihydro-3H-indol-3-ylidene)hydrazino]ethyl}[1,1'-biphenyl]-4-sulfonamide
   Show/Hide
C29H24N4O4S
 1
1
Ki = 104 nM
   TI
   LI
   LO
   TS
CP0453758
methyl 3-[[2-(4-chloro-N-[4-[3-(dimethylamino)propoxy]phenyl]sulfonylanilino)acetyl]diazenyl]-2-hydroxy-1H-indole-7-carboxylate
   Show/Hide
C29H30ClN5O7S
 1
1
Ki = 109 nM
   TI
   LI
   LO
   TS
CP0498457
CHEMBL2113205
   Show/Hide
C24H19N5O4S
 1
1
Ki = 111 nM
   TI
   LI
   LO
   TS
CP0224226
N-[2-(3,4-dihydro-1H-isoquinolin-2-yl)-2-oxoethyl]-N-(4-methoxyphenyl)benzenesulfonamide
   Show/Hide
C24H24N2O4S
 1
1
Ki = 160 nM
   TI
   LI
   LO
   TS
CP0480329
2-[N-(benzenesulfonyl)-4-chloroanilino]-N-(3-chloro-2-methylphenyl)acetamide
   Show/Hide
C21H18Cl2N2O3S
 1
1
Ki = 160 nM
   TI
   LI
   LO
   TS
CP0453759
N-[(2-hydroxy-1H-indol-3-yl)imino]-2-(4-methyl-N-naphthalen-1-ylsulfonylanilino)acetamide
   Show/Hide
C27H22N4O4S
 1
1
Ki = 174 nM
   TI
   LI
   LO
   TS
CP0916890
N'-(1-(2-hydroxyphenyl)ethylidene)-2-(N-phenylphenylsulfonamido)acetohydrazide
   Show/Hide
C22H21N3O4S
 1
1
Ki = 237 nM
   TI
   LI
   LO
   TS
CP0847573
N-(4-methylphenyl)-N-{2-oxo-2-[2-(2-oxo-1,2-dihydro-3H-indol-3-ylidene)hydrazino]ethyl}-2-naphthalenesulfonamide
   Show/Hide
C27H22N4O4S
 1
1
Ki = 239 nM
   TI
   LI
   LO
   TS
CP0493159
4-{2-[2-(3-Biphenyl-4-yl-5-methyl-[1,2,4]triazol-4-yl)-phenoxy]-ethyl}-morpholine
   Show/Hide
C27H28N4O2
 1
1
Ki = 304 nM
   TI
   LI
   LO
   TS
CP0441813
2-(2-(4-ethoxy-N-(4-methoxyphenyl)phenylsulfonamido)acetyl)-1,2,3,4-tetrahydroisoquinoline-3-carboxamide
   Show/Hide
C27H29N3O6S
 1
1
Ki = 320 nM
   TI
   LI
   LO
   TS
CP0485597
2-[3-[[2-(4-chloro-N-[4-[3-(dimethylamino)propoxy]phenyl]sulfonylanilino)acetyl]diazenyl]-2-hydroxyindol-1-yl]acetamide
   Show/Hide
C29H31ClN6O6S
 1
1
Ki = 322 nM
   TI
   LI
   LO
   TS
CP0480327
2-(N-(4-ethoxyphenyl)sulfonyl-4-methylanilino)-N-[(2-hydroxy-1H-indol-3-yl)imino]propanamide
   Show/Hide
C26H26N4O5S
 1
1
Ki = 448 nM
   TI
   LI
   LO
   TS
CP0480328
N-[2-(3,4-dihydro-1H-isoquinolin-2-yl)-2-oxoethyl]-N-(4-methylphenyl)benzenesulfonamide
   Show/Hide
C24H24N2O3S
 1
1
Ki = 470 nM
   TI
   LI
   LO
   TS
CP0391566
2-(2-(2-(4-ethoxy-N-p-tolylphenylsulfonamido)acetyl)-1,2,3,4-tetrahydroisoquinolin-3-yl)acetamide
   Show/Hide
C28H31N3O5S
 1
1
Ki = 500 nM
   TI
   LI
   LO
   TS
CP0391575
2-(2-(2-(4-ethoxy-N-(4-methoxyphenyl)phenylsulfonamido)acetyl)-1,2,3,4-tetrahydroisoquinolin-3-yl)acetamide
   Show/Hide
C28H31N3O6S
 1
1
Ki = 510 nM
   TI
   LI
   LO
   TS
CP0453757
N-(3-chloro-2-methylphenyl)-2-(N-(3,4-dimethoxyphenyl)sulfonyl-4-methylanilino)acetamide
   Show/Hide
C24H25ClN2O5S
 1
1
Ki = 620 nM
   TI
   LI
   LO
   TS
CP0467145
2-(2-(4-ethoxy-N-(4-methoxyphenyl)phenylsulfonamido)acetyl)isoindoline-1-carboxamide
   Show/Hide
C26H27N3O6S
 1
1
Ki = 770 nM
   TI
   LI
   LO
   TS
CP0393401
2-[N-(benzenesulfonyl)-4-methoxyanilino]-N-(4-chloro-2-methylphenyl)acetamide
   Show/Hide
C22H21ClN2O4S
 1
1
Ki = 800 nM
   TI
   LI
   LO
   TS
CP0377964
2-(N-(4-ethoxyphenyl)sulfonyl-4-methylanilino)-3-hydroxy-N-[(2-hydroxy-1H-indol-3-yl)imino]propanamide
   Show/Hide
C26H26N4O6S
 1
1
Ki = 1376 nM
   TI
   LI
   LO
   TS
CP0391565
2-(4-chloro-N-[4-(2-methylbutan-2-yl)phenyl]sulfonylanilino)-N-[(2-hydroxy-1H-indol-3-yl)imino]acetamide
   Show/Hide
C27H27ClN4O4S
 1
1
Ki = 1750 nM
   TI
   LI
   LO
   TS
CP0684505
N-(4-chlorophenyl)-4-ethoxy-N-(2-oxo-2-(2-(pyridin-2-ylmethylene)hydrazinyl)ethyl)benzenesulfonamide
   Show/Hide
C22H21ClN4O4S
 1
1
Ki = 2750 nM
   TI
   LI
   LO
   TS
CP0854598
2-(N-(3-chlorophenyl)phenylsulfonamido)-N'-(1-(2-hydroxyphenyl)ethylidene)acetohydrazide
   Show/Hide
C22H20ClN3O4S
 1
1
Ki = 4900 nM
   TI
   LI
   LO
   TS
CP0393402
2-[N-(benzenesulfonyl)-4-ethoxyanilino]-N-(3-chloro-2-methylphenyl)acetamide
   Show/Hide
C23H23ClN2O4S
 1
1
Ki > 10000 nM
   TI
   LI
   LO
   TS
CP0847574
4-ethoxy-N-(2-{(2E)-2-[1-(1-hydroxy-2-naphthyl)ethylidene]hydrazino}-2-oxoethyl}-N-(4-methylphenyl)benzenesulfonamide
   Show/Hide
C29H29N3O5S
 1
1
Ki > 10000 nM
   TI
   LI
   LO
   TS
CP0853634
N-(2-{2-[4-(diethylamino)-2-hydroxybenzylidene]hydrazino}-2-oxoethyl)-4-ethoxy-N-(4-methylphenyl)benzenesulfonamide
   Show/Hide
C28H34N4O5S
 1
1
Ki > 10000 nM
   TI
   LI
   LO
   TS
CP0854609
N-{2-{(E)-[2-(2-{[(4-ethoxyphenyl)sulfonyl]-4-methylanilino}acetyl)hydrazono]methyl}phenyl)acetamide
   Show/Hide
C26H28N4O5S
 1
1
Ki > 10000 nM
   TI
   LI
   LO
   TS
CP0879679
N-{2-[(2E)-2-(2-aminobenzylidene)hydrazino]-2-oxoethyl}-4-ethoxy-N-(4-methylphenyl)benzenesulfonamide
   Show/Hide
C24H26N4O4S
 1
1
Ki > 10000 nM
   TI
   LI
   LO
   TS
CP0889528
3-({[4-chloro({4-[3-(dimethylamino)propoxy]phenyl}sulfonyl)anilino]acetyl}hydrazono)-2-oxo-2,3-dihydro-1H-indole-7-carboxylic acid
   Show/Hide
C28H28ClN5O7S
 1
1
Ki > 10000 nM
   TI
   LI
   LO
   TS
CP0889529
N-(4-chlorophenyl)-4-ethoxy-N-{2-[(2E)-2-(1H-imidazol-2-ylmethylene)hydrazino]-2-oxoethyl}benzenesulfonamide
   Show/Hide
C20H20ClN5O4S
 1
1
Ki > 10000 nM
   TI
   LI
   LO
   TS
CP0889532
4-ethoxy-N-(2-{2-[(2-hydroxy-1-naphthyl)methylene]hydrazino}-2-oxoethyl}-N-(4-methylphenyl)benzenesulfonamide
   Show/Hide
C29H29N3O5S
 1
1
Ki > 10000 nM
   TI
   LI
   LO
   TS
CP0889533
3-[({[(4-ethoxyphenyl)sulfonyl]-4-methylanilino}-acetyl)hydrazono]-2-oxo-2,3-dihydro-1H-indole-5-sulfonic acid
   Show/Hide
C25H24N4O8S2
 1
1
Ki > 10000 nM
   TI
   LI
   LO
   TS
CP0889534
4-ethoxy-N-(4-methylphenyl)-N-{3-oxo-3-[2-(2-oxo-1,2-dihydro-3H-indol-3-ylidene)hydrazino]propyl}benzenesulfonamide
   Show/Hide
C26H26N4O5S
 1
1
Ki > 10000 nM
   TI
   LI
   LO
   TS
CP0904928
4-ethoxy-N-{2-[2-(5-nitro-2-oxo-1,2-dihydro-3H-indol-3-ylidene)hydrazino]-2-oxoethyl}-N-phenylbenzenesulfonamide
   Show/Hide
C24H21N5O7S
 1
1
Ki > 10000 nM
   TI
   LI
   LO
   TS
CP0910289
4-ethoxy-N-{2-[2-(5-iodo-2-oxo-1,2-dihydro-3H-indol-3-ylidene)hydrazino]-2-oxoethyl}-N-phenylbenzenesulfonamide
   Show/Hide
C24H21IN4O5S
 1
1
Ki > 10000 nM
   TI
   LI
   LO
   TS
CP0926723
N-(2-{2-[1-(2,4-dihydroxyphenyl)ethylidene]hydrazino}-2-oxoethyl)-4-ethoxy-N-(4-methylphenyl)benzenesulfonamide
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C25H27N3O6S
 1
1
Ki > 10000 nM
   TI
   LI
   LO
   TS
CP0911081
4'-methoxy-N-(4-methylphenyl)-N-{2-oxo-2-[2-(2-oxo-1,2-dihydro-3H-indol-3-ylidene)hydrazino]ethyl}[1,1'-biphenyl]-4-sulfonamide
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C30H26N4O5S
 1
1
Ki > 214 nM
   TI
   LI
   LO
   TS