Brief Information of the Cell Line and Protein
Cell Line ID: CL000063 , Hep-G2
 Cell Line Info 
Synonyms
HEP-G2
Hep G2
HEP G2
HepG2
HEPG2
Category Cancer cell line
Organism
Homo sapiens (Human)
Cellosaurus ID
CVCL_0027
Protein ID: PT01555 , Oxysterols receptor LXR-alpha
 Protein Info 
Gene Name NR1H3
Organism Homo sapiens, Human
Protein Classification Transcription factor
Uniprot ID Q13133
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000063
 Cell Line Info 
 Protein ID: PT01555
 Protein Info 
 
Compound ID Compound Name Compound Formula
CP0003740
 Compound Info 
N-[4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl]-N-(2,2,2-trifluoroethyl)benzenesulfonamide
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C17H12F9NO3S
  1
1
EC50 = 20 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0462443
 Compound Info 
2-chloro-4-[5-cyano-6-[4-[(2R)-3,3,3-trifluoro-2-hydroxy-2-phenylpropanoyl]piperazin-1-yl]pyridin-3-yl]-N,N-dimethylbenzamide
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C28H25ClF3N5O3
  1
1
EC50 = 45 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0380333
 Compound Info 
tert-butyl 4-[5-[3-chloro-4-(dimethylcarbamoyl)phenyl]-3-cyanopyridin-2-yl]piperazine-1-carboxylate
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C24H28ClN5O3
  1
1
EC50 = 280 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0535792
 Compound Info 
2-chloro-N,N-dimethyl-4-[4-[1-[(2R)-3,3,3-trifluoro-2-hydroxy-2-phenylpropanoyl]piperidin-4-yl]piperidin-1-yl]benzamide
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C28H33ClF3N3O3
  1
1
EC50 = 500 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0475688
 Compound Info 
2-chloro-4-[4-[1-[(2R)-2-hydroxy-3-methyl-2-(trifluoromethyl)butanoyl]piperidin-4-yl]piperidin-1-yl]-N,N-dimethylbenzamide
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C25H35ClF3N3O3
  1
1
EC50 = 830 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0429275
 Compound Info 
2-chloro-4-[4-[1-[(2S)-2-hydroxy-3-methyl-2-(trifluoromethyl)butanoyl]piperidin-4-yl]piperidin-1-yl]-N,N-dimethylbenzamide
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C25H35ClF3N3O3
  1
1
EC50 = 2000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS