Brief Information of the Cell Line and Protein
Cell Line ID: CL000063 , Hep-G2
Synonyms
HEP-G2
Hep G2
HEP G2
HepG2
HEPG2
Category Cancer cell line
Organism
Homo sapiens (Human)
Cellosaurus ID
CVCL_0027
Protein ID: PT00830 , Procathepsin L
Gene Name CTSL
Organism Homo sapiens, Human
Protein Classification Enzyme
Uniprot ID P07711
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000063  Protein ID: PT00830
 
Compound ID Compound Name Compound Formula
CP0060236
Balicatib
   Show/Hide
C23H33N5O2
 1
1
IC50 = 48 nM
   TI
   LI
   LO
   TS
CP0146153
(2S)-N-(cyanomethyl)-3-cyclohexyl-2-(phenylformamido)propanamide
   Show/Hide
C18H23N3O2
 1
1
IC50 = 230 nM
   TI
   LI
   LO
   TS
CP0041940
(2R)-N-(cyanomethyl)-4-methyl-2-{3-[4-(piperazin-1-yl)phenyl]phenyl}pentanamide
   Show/Hide
C24H30N4O
 1
1
IC50 = 320 nM
   TI
   LI
   LO
   TS
CP0134851
N-[1-(cyanomethylcarbamoyl)cyclohexyl]-4-[2-(4-methylpiperazin-1-yl)-1,3-thiazol-4-yl]benzamide
   Show/Hide
C24H30N6O2S
 1
1
IC50 = 340 nM
   TI
   LI
   LO
   TS
CP0077258
N-{1-[(cyanomethyl)carbamoyl]cyclohexyl}-4-[2-(morpholin-4-yl)-1,3-thiazol-4-yl]benzamide
   Show/Hide
C23H27N5O3S
 1
1
IC50 > 10000 nM
   TI
   LI
   LO
   TS
CP0077259
N-{1-[(cyanomethyl)carbamoyl]cyclohexyl}-4-(morpholin-4-yl)benzamide
   Show/Hide
C20H26N4O3
 1
1
IC50 > 10000 nM
   TI
   LI
   LO
   TS