Brief Information of the Cell Line and Protein
Cell Line ID: CL000059 , HuT 78
 Cell Line Info 
Synonyms
Hut 78
HUT 78
HuT-78
HUT-78
HuT78
Hut78
HUT78
NCI-H78
Category Cancer cell line
Organism
Homo sapiens (Human)
Cellosaurus ID
CVCL_0337
Protein ID: PT02663 , Nuclear receptor ROR-gamma
 Protein Info 
Gene Name RORC
Organism Homo sapiens, Human
Protein Classification Transcription factor
Uniprot ID P51449
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000059
 Cell Line Info 
 Protein ID: PT02663
 Protein Info 
 
Compound ID Compound Name Compound Formula
CP0402070
 Compound Info 
1-(2,6-dichlorophenyl)-2-(furan-2-yl)-5-methyl-4-(2-methylpropyl)imidazole
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C18H18Cl2N2O
  1
1
IC50 = 15 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0402072
 Compound Info 
3-[2,4-dichloro-3-[2-(5-chlorofuran-2-yl)-5-methyl-4-[1-(trifluoromethyl)cyclopropyl]imidazol-1-yl]anilino]-2,2-dimethylpropanoic acid
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C23H21Cl3F3N3O3
  1
1
IC50 = 21 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0326256
 Compound Info 
1-[2,4-dichloro-3-[2-(5-chlorofuran-2-yl)-5-methyl-4-(trifluoromethyl)imidazol-1-yl]phenyl]azetidine-3-carboxamide
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C19H14Cl3F3N4O2
  1
1
IC50 = 23 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0353090
 Compound Info 
1-[2,4-dichloro-3-[2-(5-chlorofuran-2-yl)-5-methyl-4-(2-methylpropyl)imidazol-1-yl]phenyl]azetidine-3-carboxylic acid
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C22H22Cl3N3O3
  1
1
IC50 = 32 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0402071
 Compound Info 
2-[2,4-dichloro-3-[2-cyclopropyl-5-methyl-4-[1-(trifluoromethyl)cyclopropyl]imidazol-1-yl]phenyl]-2-azaspiro[3.3]heptane-6-carboxylic acid
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C24H24Cl2F3N3O2
  1
1
IC50 = 70 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0574588
 Compound Info 
4-benzyl-1-(2,6-dichlorophenyl)-2-(furan-2-yl)-5-methylimidazole
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C21H16Cl2N2O
  1
1
IC50 = 84 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0060563
 Compound Info 
2-[1-[2,4-dichloro-3-[2-(5-chlorofuran-2-yl)-5-methyl-4-(trifluoromethyl)imidazol-1-yl]phenyl]azetidin-3-yl]acetic acid
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C20H15Cl3F3N3O3
  1
1
IC50 = 111 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0353091
 Compound Info 
2-(5-chlorofuran-2-yl)-1-(2,6-dichlorophenyl)-5-methyl-4-(trifluoromethyl)imidazole
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C15H8Cl3F3N2O
  1
1
IC50 = 189 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0096332
 Compound Info 
1-[2,4-dichloro-3-[2-(5-chlorofuran-2-yl)-5-methyl-4-(trifluoromethyl)imidazol-1-yl]phenyl]azetidine-3-carboxylic acid
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C19H13Cl3F3N3O3
  1
1
IC50 = 393 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0532485
 Compound Info 
propan-2-yl (2S)-2-[2,6-dichloro-N-(furan-2-carbonyl)anilino]propanoate
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C17H17Cl2NO4
  1
1
IC50 = 452 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS