Brief Information of the Compound and Protein
Compound Name
2-(5-chlorofuran-2-yl)-1-(2,6-dichlorophenyl)-5-methyl-4-(trifluoromethyl)imidazole
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PubChem ID
CID: 155560017
Canonical SMILES
Cc1c(nc(-c2ccc(Cl)o2)n1-c1c(Cl)cccc1Cl)C(F)(F)F
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Compound Formula C15H8Cl3F3N2O
Compound Structure
Protein Name
Nuclear receptor ROR-gamma
Protein Classification
Transcription factor
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Nuclear receptor
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Nuclear hormone receptor subfamily 1
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Nuclear hormone receptor subfamily 1 group F
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Nuclear hormone receptor subfamily 1 group F member 3
Uniprot ID
P51449
Gene Name
RORC
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000059 HuT 78 Homo sapiens (Human)  1
1
IC50 = 189 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 4 nM