Brief Information of the Cell Line and Protein
Cell Line ID: CL000058 , T-REx-293
 Cell Line Info 
Synonyms
T-REx 293
T-REx293
TRex-293
TREx293
T-REx-HEK293
T-REx HEK 293
HEK293-T-REx
HEK293-Trex
Category Transformed cell line
Organism
Homo sapiens (Human)
Cellosaurus ID
CVCL_D585
Protein ID: PT07467 , Potassium channel subfamily T member 1
 Protein Info 
Gene Name KCNT1
Organism Mus musculus, Mouse
Protein Classification Unclassified protein
Uniprot ID Q6ZPR4
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000058
 Cell Line Info 
 Protein ID: PT07467
 Protein Info 
 
Compound ID Compound Name Compound Formula
CP0537139
 Compound Info 
2-methyl-5-(trifluoromethyl)-N-[(1S)-1-[3-[2-(trifluoromethyl)pyridin-4-yl]-1,2,4-oxadiazol-5-yl]ethyl]pyrazole-3-carboxamide
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C16H12F6N6O2
  1
1
IC50 = 622 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0556950
 Compound Info 
N-[(1S)-1-[3-(2-cyclopropylpyridin-4-yl)-1,2,4-oxadiazol-5-yl]ethyl]-2-methyl-5-(trifluoromethyl)pyrazole-3-carboxamide
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C18H17F3N6O2
  1
1
IC50 = 1143 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0565077
 Compound Info 
N-[(1S)-1-[3-[2-(difluoromethyl)pyridin-4-yl]-1,2,4-oxadiazol-5-yl]ethyl]-2-methyl-5-(trifluoromethyl)pyrazole-3-carboxamide
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C16H13F5N6O2
  1
1
IC50 = 1251 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0444680
 Compound Info 
N-[(1S)-1-[3-(2-methoxypyridin-4-yl)-1,2,4-oxadiazol-5-yl]ethyl]-2-methyl-5-(trifluoromethyl)pyrazole-3-carboxamide
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C16H15F3N6O3
  1
1
IC50 = 3001 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0563812
 Compound Info 
2-methyl-N-[(1S)-1-[3-(2-methylpyridin-4-yl)-1,2,4-oxadiazol-5-yl]ethyl]-5-(trifluoromethyl)pyrazole-3-carboxamide
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C16H15F3N6O2
  1
1
IC50 = 14500 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0551767
 Compound Info 
N-[(1S)-1-[3-[2-(methoxymethyl)pyridin-4-yl]-1,2,4-oxadiazol-5-yl]ethyl]-2-methyl-5-(trifluoromethyl)pyrazole-3-carboxamide
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C17H17F3N6O3
  1
1
IC50 = 17140 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0451217
 Compound Info 
2-methyl-N-[(1S)-1-[3-[2-(methylamino)pyridin-4-yl]-1,2,4-oxadiazol-5-yl]ethyl]-5-(trifluoromethyl)pyrazole-3-carboxamide
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C16H16F3N7O2
  1
1
IC50 > 30000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS