Brief Information of the Cell Line and Protein
Cell Line ID: CL000058 , T-REx-293
Synonyms
T-REx 293
T-REx293
TRex-293
TREx293
T-REx-HEK293
T-REx HEK 293
HEK293-T-REx
HEK293-Trex
Category Transformed cell line
Organism
Homo sapiens (Human)
Cellosaurus ID
CVCL_D585
Protein ID: PT00854 , Metabotropic glutamate receptor 5
Gene Name GRM5
Organism Homo sapiens, Human
Protein Classification Membrane receptor
Uniprot ID P41594
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000058  Protein ID: PT00854
 
Compound ID Compound Name Compound Formula
CP0416254
7-(4-fluorophenyl)-2-[[2-(trifluoromethyl)pyridin-4-yl]oxymethyl]pyrazolo[1,5-a]pyrimidine-5-carboxamide
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C20H13F4N5O2
 1
1
IC50 > 30000 nM
   TI
   LI
   LO
   TS
CP0416287
2-[[(2R,6S)-2,6-dimethylmorpholin-4-yl]methyl]-7-(4-fluorophenyl)thieno[3,2-b]pyridine-5-carboxamide
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C21H22FN3O2S
 1
1
IC50 > 30000 nM
   TI
   LI
   LO
   TS
CP0432623
3-[(2-methyl-4-thiazolyl)ethynyl]benzonitrile
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C13H8N2S
 1
1
Ki = 0.37 nM
   TI
   LI
   LO
   TS
CP0500672
3-[(2-methyl-4-thiazolyl)ethynyl]-5-vinylpyridine
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C13H10N2S
 1
1
Ki = 1.003 nM
   TI
   LI
   LO
   TS