Brief Information of the Cell Line and Protein
Cell Line ID: CL000053 , COS-7
Synonyms
Cos-7
COS 7
Cos 7
COS7
Cos7
CV-1 in Origin Simian-7
Category Transformed cell line
Organism
Chlorocebus aethiops (Green monkey)
Cellosaurus ID
CVCL_0224
Protein ID: PT05184 , Steroid 21-hydroxylase
Gene Name CYP21A2
Organism Homo sapiens, Human
Protein Classification Enzyme
Uniprot ID P08686
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000053  Protein ID: PT05184
 
Compound ID Compound Name Compound Formula
CP0133117
1-cyclopropyl-5,6-difluoro-2-(5-fluoropyridin-3-yl)benzimidazole
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C15H10F3N3
 1
1
IC50 > 10000 nM
   TI
   LI
   LO
   TS
CP0401274
1-cyclopropyl-5,6-difluoro-2-(5-fluoro-4-methylpyridin-3-yl)benzimidazole
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C16H12F3N3
 1
1
IC50 > 10000 nM
   TI
   LI
   LO
   TS
CP0643522
2-(5-(1-cyclopropyl-6-fluoro-1H-benzo[d]imidazol-2-yl)pyridin-3-yl)propan-2-ol
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C18H18FN3O
 1
1
IC50 > 10000 nM
   TI
   LI
   LO
   TS
CP0667085
2-(5-(1-cyclopropyl-5,6-difluoro-1H-benzo[d]imidazol-2-yl)pyridin-3-yl)propan-2-ol
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C18H17F2N3O
 1
1
IC50 > 10000 nM
   TI
   LI
   LO
   TS
CP0048211
3-cyclopropyl-2-(4-ethyl-5-fluoropyridin-3-yl)-6-fluoroimidazo[1,2-a]pyridine
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C17H15F2N3
 1
1
IC50 > 10000 nM
   TI
   LI
   LO
   TS
CP0091722
4-(3-cyclopropyl-6-fluoroimidazo[1,2-a]pyridin-2-yl)isoquinoline
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C19H14FN3
 1
1
IC50 > 10000 nM
   TI
   LI
   LO
   TS
CP0190103
3-cyclopropyl-6-fluoro-2-(5-fluoropyridin-3-yl)imidazo[1,2-a]pyridine
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C15H11F2N3
 1
1
IC50 > 10000 nM
   TI
   LI
   LO
   TS
CP0190104
3-cyclopropyl-6-fluoro-2-(5-fluoro-4-methylpyridin-3-yl)imidazo[1,2-a]pyridine
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C16H13F2N3
 1
1
IC50 > 10000 nM
   TI
   LI
   LO
   TS
CP0294276
(2S)-2-[5-(3-cyclopropyl-6-fluoroimidazo[1,2-a]pyridin-2-yl)pyridin-3-yl]-1,1,1-trifluoropropan-2-ol
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C18H15F4N3O
 1
1
IC50 > 10000 nM
   TI
   LI
   LO
   TS
CP0108244
(2R)-1,1,1-trifluoro-2-[5-(3-methylindazol-1-yl)pyridin-3-yl]propan-2-ol
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C16H14F3N3O
 1
1
IC50 > 10000 nM
   TI
   LI
   LO
   TS
CP0180854
2-[5-[4-(trifluoromethyl)indazol-1-yl]pyridin-3-yl]propan-2-ol
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C16H14F3N3O
 1
1
IC50 > 10000 nM
   TI
   LI
   LO
   TS
CP0201912
2-[5-(4-fluoro-3-methylindazol-1-yl)pyridin-3-yl]propan-2-ol
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C16H16FN3O
 1
1
IC50 > 10000 nM
   TI
   LI
   LO
   TS
CP0240397
(2S)-1,1,1-trifluoro-2-[5-[3-(trifluoromethyl)indazol-1-yl]pyridin-3-yl]propan-2-ol
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C16H11F6N3O
 1
1
IC50 > 10000 nM
   TI
   LI
   LO
   TS
CP0244010
(2S)-1,1,1-trifluoro-2-[5-(3-methylindazol-1-yl)pyridin-3-yl]propan-2-ol
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C16H14F3N3O
 1
1
IC50 > 10000 nM
   TI
   LI
   LO
   TS