Brief Information of the Cell Line and Protein
Cell Line ID: CL000053 , COS-7
Synonyms
Cos-7
COS 7
Cos 7
COS7
Cos7
CV-1 in Origin Simian-7
Category Transformed cell line
Organism
Chlorocebus aethiops (Green monkey)
Cellosaurus ID
CVCL_0224
Protein ID: PT04933 , Diacylglycerol lipase-alpha
Gene Name DAGLA
Organism Homo sapiens, Human
Protein Classification Enzyme
Uniprot ID Q9Y4D2
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000053  Protein ID: PT04933
 
Compound ID Compound Name Compound Formula
CP0423365
[(2S)-1-[(2S,3S)-3-hexyl-4-oxooxetan-2-yl]tridecan-2-yl] (2S)-2-formamido-3-methylpentanoate
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C29H53NO5
 1
1
IC50 = 16 nM
   TI
   LI
   LO
   TS
CP0439729
[(2S)-1-[(2S,3S)-3-hexyl-4-oxooxetan-2-yl]tridecan-2-yl] (2S)-2-formamido-3-methylbutanoate
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C28H51NO5
 1
1
IC50 = 35 nM
   TI
   LI
   LO
   TS
CP0485042
[(2S)-1-[(2S,3S)-3-hexyl-4-oxooxetan-2-yl]tridecan-2-yl] (2S)-2-formamidopropanoate
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C26H47NO5
 1
1
IC50 = 43 nM
   TI
   LI
   LO
   TS
CP0433844
5-oxo-L-Proline-(1S)-1-[[(2S,3S)-3-hexyl-4-oxo-2-oxetanyl]methyl]dodecyl Ester
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C27H47NO5
 1
1
IC50 = 100 nM
   TI
   LI
   LO
   TS
CP0511846
[(2S)-1-[(2S,3S)-3-hexyl-4-oxooxetan-2-yl]tridecan-2-yl] (2S)-2-acetamido-3-methylpentanoate
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C30H55NO5
 1
1
IC50 = 430 nM
   TI
   LI
   LO
   TS
CP0506288
[(2S)-1-[(2S,3S)-3-hexyl-4-oxooxetan-2-yl]tridecan-2-yl] (2S)-2-acetamido-3-methylbutanoate
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C29H53NO5
 1
1
IC50 = 460 nM
   TI
   LI
   LO
   TS
CP0465926
[(2S)-1-[(2S,3S)-3-hexyl-4-oxooxetan-2-yl]tridecan-2-yl] 3-formamidopropanoate
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C26H47NO5
 1
1
IC50 = 600 nM
   TI
   LI
   LO
   TS
CP0423366
[(2S)-1-[(2S,3S)-3-hexyl-4-oxooxetan-2-yl]tridecan-2-yl] 2-acetamidoacetate
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C26H47NO5
 1
1
IC50 = 800 nM
   TI
   LI
   LO
   TS
CP0489860
[(2S)-1-[(2S,3S)-3-hexyl-4-oxooxetan-2-yl]tridecan-2-yl] (2S)-1-formylpyrrolidine-2-carboxylate
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C28H49NO5
 1
1
IC50 = 1100 nM
   TI
   LI
   LO
   TS
CP0485066
(1R)-1-{[(2S,3S)-3-hexyl-4-oxooxetan-2-yl]methyl}dodecyl N-formylglycinate
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C25H45NO5
 1
1
IC50 = 2800 nM
   TI
   LI
   LO
   TS
CP0135864
[(2S)-1-[(2S,3S)-3-hexyl-4-oxooxetan-2-yl]tridecan-2-yl] (2R)-2-formamido-4-methylpentanoate
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C29H53NO5
 1
1
IC50 = 5000 nM
   TI
   LI
   LO
   TS
CP0423377
[(2S)-1-[(2S,3S)-3-hexyl-4-oxooxetan-2-yl]tridecan-2-yl] (2S)-2-amino-4-methylpentanoate
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C28H53NO4
 1
1
IC50 > 25000 nM
   TI
   LI
   LO
   TS
CP0423378
[(2S)-1-[(2S,3S)-3-hexyl-4-oxooxetan-2-yl]tridecan-2-yl] (2S)-3-phenyl-2-(phenylmethoxycarbonylamino)propanoate
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C39H57NO6
 1
1
IC50 > 25000 nM
   TI
   LI
   LO
   TS
CP0439254
[(2S)-1-[(2S,3S)-3-hexyl-4-oxooxetan-2-yl]tridecan-2-yl] (2S)-2-formamido-3-phenylpropanoate
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C32H51NO5
 1
1
IC50 = 25000 nM
   TI
   LI
   LO
   TS
CP0439255
[(2S)-1-[(2S,3S)-3-hexyl-4-oxooxetan-2-yl]tridecan-2-yl] 2-(phenylmethoxycarbonylamino)acetate
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C32H51NO6
 1
1
IC50 > 25000 nM
   TI
   LI
   LO
   TS
CP0439730
[(2S)-1-[(2S,3S)-3-hexyl-4-oxooxetan-2-yl]tridecan-2-yl] (2S)-4-methyl-2-[(2-methylpropan-2-yl)oxycarbonylamino]pentanoate
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C33H61NO6
 1
1
IC50 > 25000 nM
   TI
   LI
   LO
   TS
CP0465929
(3S,4S)-3-Hexyl-4-[(2S)-2-hydroxytridecyl]oxetan-2-one
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C22H42O3
 1
1
IC50 = 25000 nM
   TI
   LI
   LO
   TS
CP0465931
[(2S)-1-[(2S,3S)-3-hexyl-4-oxooxetan-2-yl]tridecan-2-yl] (2S)-4-methyl-2-(phenylmethoxycarbonylamino)pentanoate
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C36H59NO6
 1
1
IC50 > 25000 nM
   TI
   LI
   LO
   TS
CP0465932
4-Methylpentanoic Acid (1S)-1-[[(2S,3S-3-Hexyl-4-oxo-2-oxetanyl]methyl]dodecyl Ester
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C28H52O4
 1
1
IC50 > 25000 nM
   TI
   LI
   LO
   TS
CP0485044
[(2S)-1-[(2S,3S)-3-hexyl-4-oxooxetan-2-yl]tridecan-2-yl] (2R)-4-methyl-2-(phenylmethoxycarbonylamino)pentanoate
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C36H59NO6
 1
1
IC50 > 25000 nM
   TI
   LI
   LO
   TS
CP0500741
[(2S)-1-[(2S,3S)-3-hexyl-4-oxooxetan-2-yl]tridecan-2-yl] (2S)-2-amino-3-phenylpropanoate
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C31H51NO4
 1
1
IC50 = 25000 nM
   TI
   LI
   LO
   TS